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20 Most Recent Compounds

FORMULA:C34H47N3O4

SMILES: Cc1ccccc1CNC(=O)CNC(=O)[C@@H](CC(C)C)NC(=O)c1ccc2c(c1)CCCCOCCC=CCCC2

BIRTHDAY: 2018-12-25T02:04:10.832042
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
RECEPTOR: Histone deacetylase

Synthesis Plan
FORMULA:C27H29N5O2S

SMILES: CC(C)C[C@H]1CCCOc2cccc(c2)-c2cc(nc(-n3ccnn3)n2)Sc2cccc(c2)OC1

BIRTHDAY: 2018-12-25T02:02:21.011334
ATC: B03X
- BLOOD AND BLOOD FORMING ORGANS
- ANTIANEMIC PREPARATIONS
- OTHER ANTIANEMIC PREPARATIONS
RECEPTOR: A0A024R4G4

Synthesis Plan
FORMULA:C22H24N4O5

SMILES: COc1ccc(C(=O)Nc2ccc(C(=O)N[C@]3(C(N)=O)[C@H]4CCCN3CO4)cc2)cc1

BIRTHDAY: 2018-12-25T02:03:53.121444
ATC: D01A
- DERMATOLOGICALS
- ANTIFUNGALS FOR DERMATOLOGICAL USE
- ANTIFUNGALS FOR TOPICAL USE
RECEPTOR: T cell receptor alpha variable 4

Synthesis Plan
FORMULA:C40H63N3

SMILES: C[C@H](CCCCCCCCCCN(C)Cc1ccccc1)CCCCCCNC1=c2ccccc2=NC2(CCCCC2)C1

BIRTHDAY: 2018-12-25T02:04:13.307921
ATC: S01F
- SENSORY ORGANS
- OPHTHALMOLOGICALS
- MYDRIATICS AND CYCLOPLEGICS
RECEPTOR: 5-hydroxytryptamine receptor 3E

Synthesis Plan
FORMULA:C23H24N6S

SMILES: CC(C)(C)c1ccc(Nc2cnc(Nc3ccccc3C3=CNSN=C3)nc2)cc1

BIRTHDAY: 2018-12-25T02:03:31.566236
ATC: M01A
- MUSCULO-SKELETAL SYSTEM
- ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS
- ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS
RECEPTOR: Fms-related tyrosine kinase 1

Synthesis Plan
FORMULA:C24H23F3N4O3

SMILES: COc1ccccc1C(=O)Nc1c(C)cccc1-c1c(N2CCOCC2)ncnc1C(F)(F)F

BIRTHDAY: 2018-12-25T02:02:51.609158
ATC: C10A
- CARDIOVASCULAR SYSTEM
- LIPID MODIFYING AGENTS
- LIPID MODIFYING AGENTS, PLAIN
RECEPTOR: Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform

Synthesis Plan
FORMULA:C14H16N2O2

SMILES: CC(C)(C)c1cccc(-c2ncoc(=O)c2N)c1

BIRTHDAY: 2018-12-25T02:03:34.445280
ATC: C01B
- CARDIOVASCULAR SYSTEM
- CARDIAC THERAPY
- ANTIARRHYTHMICS, CLASS I AND III
RECEPTOR: Phosphatidylinositol 3-kinase regulatory subunit beta

Synthesis Plan
FORMULA:C22H44N2O2

SMILES: CCCCCCCCCCCCCCCCCCCC(=O)NCC(N)=O

BIRTHDAY: 2018-12-25T02:02:46.263904
ATC: S01A
- SENSORY ORGANS
- OPHTHALMOLOGICALS
- ANTIINFECTIVES
RECEPTOR: Nuclear receptor subfamily 5 group A member 2

Synthesis Plan
FORMULA:C24H16F3NO3

SMILES: O=C(c1ccccc1OCc1ccccc1)c1ocnc1-c1ccccc1C(F)(F)F

BIRTHDAY: 2018-12-25T02:03:20.162091
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
RECEPTOR: Fatty-acid amide hydrolase 1

Synthesis Plan
FORMULA:C30H31NO3

SMILES: COc1cccc2c1[C@]1(NC(=O)c3cccc(-c4ccccc4C(C)C)c3)CCCC=C(C2)O1

BIRTHDAY: 2018-12-25T02:03:08.757351
ATC: R02A
- RESPIRATORY SYSTEM
- THROAT PREPARATIONS
- THROAT PREPARATIONS
RECEPTOR: Acetyl-CoA carboxylase 2

Synthesis Plan
FORMULA:C21H24N2O4

SMILES: Cc1c(NC(=O)c2cccc(NC(=O)CC(C)C)c2)ccc(C(=O)O)c1C

BIRTHDAY: 2018-12-25T02:03:04.862413
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
RECEPTOR: Prostaglandin E synthase

Synthesis Plan
FORMULA:C28H47N3O4

SMILES: CCCCCCCCCCCCCCCCCCC(=O)Nc1ccc(/C(N)=N/OCC(=O)O)cc1

BIRTHDAY: 2018-12-25T02:02:45.798564
ATC: N06A
- NERVOUS SYSTEM
- PSYCHOANALEPTICS
- ANTIDEPRESSANTS
RECEPTOR: Apoptotic protease-activating factor 1

Synthesis Plan
FORMULA:C19H12N4OS2

SMILES: N#Cc1c(NC(=O)Nc2ccc(-c3cccnc3)cc2)sc2ccsc12

BIRTHDAY: 2018-12-25T02:03:07.743111
ATC: C10A
- CARDIOVASCULAR SYSTEM
- LIPID MODIFYING AGENTS
- LIPID MODIFYING AGENTS, PLAIN
RECEPTOR: Serine/threonine-protein kinase Chk1

Synthesis Plan
FORMULA:C17H20N2O4

SMILES: CC(C)C[C@@H](NC(=O)c1ccc(C(=O)O)cc1)C1=NCOC=C1

BIRTHDAY: 2018-12-25T02:03:07.450974
ATC: P03B
- ANTIPARASITIC PRODUCTS, INSECTICIDES AND REPELLENTS
- ECTOPARASITICIDES, INCL. SCABICIDES, INSECTICIDES AND REPELLENTS
- INSECTICIDES AND REPELLENTS
RECEPTOR: Neuropilin-1

Synthesis Plan
FORMULA:C23H22O4

SMILES: COc1ccc(-c2cccc(COc3ccc(CCC(=O)O)cc3)c2)cc1

BIRTHDAY: 2018-12-25T02:03:11.655626
ATC: R03D
- RESPIRATORY SYSTEM
- DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES
- OTHER SYSTEMIC DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES
RECEPTOR: Free fatty acid receptor 1

Synthesis Plan
FORMULA:C26H33N7O2

SMILES: C[C@@H](Nc1cnccc1-c1cnccc1NC(=O)c1ccccc1O[C@H]1CCN[C@@H](N)C1)N(C)C

BIRTHDAY: 2018-12-25T02:02:52.723119
ATC: N05A
- NERVOUS SYSTEM
- PSYCHOLEPTICS
- ANTIPSYCHOTICS
RECEPTOR: Inhibitor of nuclear factor kappa-B kinase subunit beta

Synthesis Plan
FORMULA:C24H20F3N5O2

SMILES: NC(=O)[C@@]12C=CC=C[C@@H]1C=NC(NCc1ccc(NC(=O)c3ccccc3C(F)(F)F)cc1)=N2

BIRTHDAY: 2018-12-25T02:02:57.093239
ATC: P01A
- ANTIPARASITIC PRODUCTS, INSECTICIDES AND REPELLENTS
- ANTIPROTOZOALS
- AGENTS AGAINST AMOEBIASIS AND OTHER PROTOZOAL DISEASES
RECEPTOR: Aurora kinase A

Synthesis Plan
FORMULA:C20H26N6O3

SMILES: CC(C)[C@H](N)C(=O)N[C@H](CCC(N)=O)c1cc(-c2ccccc2C(N)=O)ncn1

BIRTHDAY: 2018-12-25T02:02:30.227207
ATC: A02B
- ALIMENTARY TRACT AND METABOLISM
- DRUGS FOR ACID RELATED DISORDERS
- DRUGS FOR PEPTIC ULCER AND GASTRO-OESOPHAGEAL REFLUX DISEASE (GORD)
RECEPTOR: Inhibitor of nuclear factor kappa-B kinase subunit alpha

Synthesis Plan
FORMULA:C18H27N3O2

SMILES: CC(C)(C)OC(=O)N[C@H]1C2CCN(CC2)[C@@H]1Cc1cccnc1

BIRTHDAY: 2018-12-25T02:02:46.427223
ATC: B06A
- BLOOD AND BLOOD FORMING ORGANS
- OTHER HEMATOLOGICAL AGENTS
- OTHER HEMATOLOGICAL AGENTS
RECEPTOR: Phosphomannomutase 2

Synthesis Plan
FORMULA:C38H61NO

SMILES: CCCCCCCCCCCCCCCCCCCCCCCCCC(=O)Nc1ccc(-c2ccccc2)cc1

BIRTHDAY: 2018-12-25T02:03:52.849004
ATC: M01A
- MUSCULO-SKELETAL SYSTEM
- ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS
- ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS
RECEPTOR: Histone deacetylase 3

Synthesis Plan

All Receptors

Disease data sourced from Pharos.

Histone deacetylase
No disease data available for this receptor.
A0A024R4G4
May affect: carcinoma; netherton syndrome; rosacea...
T cell receptor alpha variable 4
No disease data available for this receptor.
5-hydroxytryptamine receptor 3E
May affect: carcinoma; irritable bowel syndrome; dyspepsia...
Fms-related tyrosine kinase 1
No disease data available for this receptor.
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
May affect: carcinoma; schizophrenia; atrial fibrillation...
Phosphatidylinositol 3-kinase regulatory subunit beta
May affect: carcinoma; polydactyly; syndactyly...
Nuclear receptor subfamily 5 group A member 2
May affect: osteoporosis; pancreatic cancer; carcinoma...
Fatty-acid amide hydrolase 1
May affect: carcinoma; pain agnosia; cannabis dependence...
Acetyl-CoA carboxylase 2
May affect: endometrial cancer; breast cancer; kidney cancer...
Prostaglandin E synthase
May affect: arthritis; cancer; cerebrovascular disease...
Apoptotic protease-activating factor 1
May affect: kidney cancer; carcinoma; cancer...
Serine/threonine-protein kinase Chk1
May affect: carcinoma; cancer; ataxia telangiectasia...
Neuropilin-1
May affect: carcinoma; cancer; acute hemorrhagic leukoencephalitis...
Free fatty acid receptor 1
May affect: diabetes mellitus; hypoglycemia; obesity...
Inhibitor of nuclear factor kappa-B kinase subunit beta
May affect: severe combined immunodeficiency; carcinoma; cancer...
Aurora kinase A
May affect: cancer; measles; retinitis pigmentosa 62...
Inhibitor of nuclear factor kappa-B kinase subunit alpha
May affect: kidney cancer; carcinoma; type 2 diabetes mellitus...
Phosphomannomutase 2
May affect: congenital disorder of glycosylation; digeorge syndrome; multiple congenital anomalies-hypotonia-seizures syndrome 3...
Histone deacetylase 3
May affect: cancer; neuronal ceroid lipofuscinosis 2; heart diseases...
3-phosphoinositide-dependent protein kinase 1
May affect: cancer; glaucoma; heart failure...
Voltage-dependent T-type calcium channel subunit alpha-1G
May affect: neurodegenerative disease; autosomal dominant cerebellar ataxia; carcinoma...
Bcl-2-like protein 11
May affect: atopic dermatitis; cholangitis; cancer...
Carbonic anhydrase 12
May affect: carcinoma; cancer; dehydration...
Orexin receptor type 1
May affect: narcolepsy; seasonal affective disorder; pain agnosia...
Orexin receptor type 2
May affect: melanoma; kidney cancer; carcinoma...
Perilipin-1
May affect: familial partial lipodystrophy; carcinoma; obesity...
Lysine-specific histone demethylase 1A
May affect: carcinoma; cancer; non-small cell lung carcinoma...
Cyclin-T1
May affect: carcinoma; acquired immunodeficiency syndrome; acute myeloid leukemia...
Tyrosine-protein kinase JAK2
May affect: cancer; essential thrombocythemia; myelofibrosis...
Protein-S-isoprenylcysteine O-methyltransferase
May affect: prostatitis; legionnaires' disease; progeria...
Galanin receptor type 3
May affect: alcoholic intoxication, chronic; alcohol abuse; multiple sclerosis...
Rho-associated protein kinase 2
May affect: heart disease; kidney cancer; carcinoma...
Serine/threonine-protein kinase/endoribonuclease IRE1
May affect: carcinoma; chromosome 6pter-p24 deletion syndrome; cancer...
Nuclear receptor subfamily 1 group I member 2
May affect: malaria; carcinoma; cholestasis...
PC4 and SFRS1-interacting protein
May affect: carcinoma; acquired immunodeficiency syndrome; cancer...
cGMP-specific 3',5'-cyclic phosphodiesterase
May affect: carcinoma; impotence; premature ejaculation...
G2/mitotic-specific cyclin-B2
May affect: carcinoma; anauxetic dysplasia; cancer...
Sphingosine 1-phosphate receptor 2
May affect: nonsyndromic deafness; autosomal recessive nonsyndromic deafness 68; vascular disease...
5-hydroxytryptamine receptor 3B
May affect: heroin dependence; irritable bowel syndrome; alcohol dependence...
Tyrosyl-DNA phosphodiesterase 2
May affect: intellectual disability; neurodegenerative disease; autosomal dominant cerebellar ataxia...
Malonyl-CoA decarboxylase, mitochondrial
May affect: carcinoma; isovaleric acidemia; propionic acidemia...
Sphingosine 1-phosphate receptor 4
May affect: carcinoma; multiple sclerosis; diabetes mellitus, experimental...
Serine/threonine-protein kinase PAK 4
May affect: carcinoma; cancer; breast adenoma...
Serine/threonine-protein kinase Chk2
May affect: prostate cancer; breast cancer; cancer...
Dihydrofolate reductase
May affect: malaria; cancer; pneumocystosis...
Purine nucleoside phosphorylase
May affect: purine nucleoside phosphorylase deficiency; schizophrenia; schizoaffective disorder...
Tyrosine-protein kinase ABL1
May affect: cancer; chronic myeloid leukemia; immune system cancer...
Epidermal growth factor receptor
May affect: lung cancer; cancer; immune system cancer...
Prothrombin
May affect: prothrombin deficiency; thrombophilia; carcinoma...
Coagulation factor X
May affect: factor x deficiency; carcinoma; carney complex...
Plasminogen
May affect: thrombophilia; melanoma; atherosclerosis...
Urokinase-type plasminogen activator
May affect: substance-related disorder; carcinoma; crohn's disease...
Tissue-type plasminogen activator
May affect: carcinoma; cerebrovascular disease; myocardial infarction...
Renin
May affect: carcinoma; hypertension; conn's syndrome...
Carbonic anhydrase 1
May affect: central sleep apnea; glaucoma; transient global amnesia...
Carbonic anhydrase 2
May affect: osteopetrosis; renal tubular acidosis; 3p- syndrome...
Tumor necrosis factor
May affect: guillain-barre syndrome; juvenile rheumatoid arthritis; narcolepsy...
Retinol-binding protein 4
May affect: microphthalmia; obesity; diabetes mellitus...
Estrogen receptor
May affect: acquired metabolic disease; heart disease; osteoporosis...
Coagulation factor XI
May affect: factor xi deficiency; vascular disease; carcinoma...
RAF proto-oncogene serine/threonine-protein kinase
May affect: cardiomyopathy; leopard syndrome; cancer...
Glucosylceramidase
May affect: lewy body dementia; neurodegenerative disease; parkinson's disease...
Thymidylate synthase
May affect: cancer; alzheimer's disease 8; diarrhea...
Amyloid-beta A4 protein
May affect: alzheimer's disease; neurodegenerative disease; amyloidosis...
Steroid 17-alpha-hydroxylase/17,20 lyase
May affect: essential hypertension; parkinson's disease; congenital adrenal hyperplasia...
Integrin beta-3
May affect: osteopetrosis; glanzmann's thrombasthenia; breast cancer...
Cytochrome P450 1A2
May affect: cardiovascular system disease; substance-related disorder; carcinoma...
Alkaline phosphatase, tissue-nonspecific isozyme
May affect: hypophosphatasia; disease of metabolism; carcinoma...
Intercellular adhesion molecule 1
May affect: atherosclerosis; carcinoma; cancer...
Integrin beta-1
May affect: mental depression; carcinoma; schizophrenia...
Protein kinase C beta type
May affect: lung cancer; kidney cancer; carcinoma...
Insulin receptor
May affect: donohue syndrome; polycystic ovary syndrome; diabetes mellitus...
Tyrosine-protein kinase Lck
May affect: cancer; carcinoma; lymphopenia...
Cholinesterase
May affect: acquired metabolic disease; alzheimer's disease; cardiovascular system disease...
P06492
No disease data available for this receptor.
Cyclin-dependent kinase 1
May affect: type 2 diabetes mellitus; cancer; neuronal ceroid lipofuscinosis...
Glycogen phosphorylase, liver form
May affect: glycogen storage disease; glycogen storage disease vi; lymphoid leukemia...
Epoxide hydrolase 1
May affect: carcinoma; chronic obstructive pulmonary disease; cancer...
Macrophage colony-stimulating factor 1 receptor
May affect: cancer; immune system cancer; brain cancer...
Cathepsin D
May affect: neuronal ceroid lipofuscinosis 10; alzheimer's disease; neurodegenerative disease...
Calpain-1 catalytic subunit
May affect: neurodegenerative disease; hereditary spastic paraplegia; carcinoma...
Trypsin-1
May affect: carcinoma; pancreatitis; pancreatic cancer...
Trypsin-2
May affect: pancreatitis, chronic; hereditary pancreatitis; pancreatitis, hereditary...
Beta-2 adrenergic receptor
May affect: carcinoma; asthma; chronic obstructive pulmonary disease...
Cathepsin L1
May affect: carcinoma; fascioliasis; gelatinous drop-like corneal dystrophy...
Cathepsin B
May affect: parkinson's disease; carcinoma; cancer...
Heat shock protein HSP 90-alpha
May affect: carcinoma; cancer; henoch-schoenlein purpura...
Tyrosine-protein kinase Lyn
May affect: cancer; carcinoma; lupus erythematosus...
Proto-oncogene tyrosine-protein kinase receptor Ret
May affect: paraganglioma; hirschsprung's disease; lung cancer...
Insulin-like growth factor 1 receptor
May affect: degenerative disc disease; gout; kidney cancer...
Muscarinic acetylcholine receptor M2
May affect: alcohol dependence; kidney cancer; carcinoma...
Mineralocorticoid receptor
May affect: acquired metabolic disease; corneal disease; kidney cancer...
Heat shock protein HSP 90-beta
May affect: carcinoma; cancer; hiv infections...
Neutrophil elastase
May affect: severe congenital neutropenia; cyclic hematopoiesis; lung disease...
Cathepsin G
May affect: carcinoma; wegener's granulomatosis; vasculitis...
Integrin alpha-IIb
May affect: glanzmann's thrombasthenia; kidney cancer; carcinoma...
Hepatocyte growth factor receptor
May affect: nonsyndromic deafness; lung cancer; cancer...
Beta-1 adrenergic receptor
May affect: essential hypertension; lipid storage disease; heart disease...
Cytochrome P450 3A4
May affect: carcinoma; cancer; liver disease...
Steryl-sulfatase
May affect: carcinoma; x-linked ichthyosis; ichthyosis...
5-hydroxytryptamine receptor 1A
May affect: carcinoma; anxiety disorder; schizophrenia...
Muscarinic acetylcholine receptor M5
May affect: carcinoma; myopia; marijuana abuse...
Alpha-2A adrenergic receptor
May affect: familial partial lipodystrophy; acquired metabolic disease; disease of mental health...
Matrilysin
May affect: prostate cancer; cancer; pneumonia...
Fructose-1,6-bisphosphatase 1
May affect: fructose-1,6-bisphosphatase deficiency; lactic acidosis; apnea...
Glutathione S-transferase Mu 1
May affect: cancer; xeroderma pigmentosum group d; pain agnosia...
Platelet-derived growth factor receptor beta
May affect: cancer; carcinoma; hypereosinophilic syndrome...
Complement C1s subcomponent
May affect: ehlers-danlos syndrome; melanoma; carcinoma...
Arachidonate 5-lipoxygenase
May affect: carcinoma; asthma; cancer...
Intestinal-type alkaline phosphatase
May affect: carcinoma; obstructive jaundice; tick infestation...
Adenosine receptor A3
May affect: carcinoma; vascular disease; reflex epilepsy...
Androgen receptor
May affect: androgenic alopecia; kennedy's disease; prostate cancer...
Retinoic acid receptor alpha
May affect: acute promyelocytic leukemia; cancer; carcinoma...
Apoptosis regulator Bcl-2
May affect: cancer; immune system cancer; lymphoid leukemia...
Cytochrome P450 2D6
May affect: carcinoma; autoimmune hepatitis; cancer...
Alkaline phosphatase, germ cell type
May affect: carcinoma; obstructive jaundice; tick infestation...
Mast/stem cell growth factor receptor Kit
May affect: cancer; piebaldism; gastrointestinal stromal tumor...
Retinoic acid receptor beta
May affect: microphthalmia; cancer; cognitive disorder...
Thyroid hormone receptor alpha
May affect: congenital hypothyroidism; carcinoma; hypothyroidism...
Thyroid hormone receptor beta
May affect: carcinoma; peripheral vascular disease; hypothyroidism...
Fibroblast growth factor receptor 1
May affect: intellectual disability; pfeiffer syndrome; klinefelter's syndrome...
DNA topoisomerase 1
May affect: cancer; kidney cancer; carcinoma...
Cytochrome P450 2A6
May affect: carcinoma; nicotine dependence; cancer...
Aromatase
May affect: breast cancer; pseudohermaphroditism; alzheimer's disease...
Cholesteryl ester transfer protein
May affect: age related macular degeneration; atherosclerosis; acquired metabolic disease...
Cytochrome P450 2C9
May affect: melanoma; carcinoma; skin cancer...
Cyclin-dependent kinase 4
May affect: carcinoma; cancer; lipoma...
Polyadenylate-binding protein 1
May affect: substance-related disorder; carcinoma; premature ovarian failure...
Inosine-5'-monophosphate dehydrogenase 2
May affect: carcinoma; bartter disease type 3; acute quadriplegic myopathy...
Angiotensin-converting enzyme
May affect: carcinoma; hypertension; coronary artery disease...
Bone morphogenetic protein 1
May affect: osteogenesis imperfecta; carcinoma; dentinogenesis imperfecta...
Integrin alpha-4
May affect: kidney cancer; testicular cancer; carcinoma...
Retinoic acid receptor gamma
May affect: carcinoma; paraneoplastic polyneuropathy; cancer...
Sodium/glucose cotransporter 1
May affect: carcinoma; diabetes mellitus; diarrhea...
Beta-3 adrenergic receptor
May affect: diabetes mellitus; obesity; hypertension...
Macrophage migration inhibitory factor
May affect: juvenile rheumatoid arthritis; cancer; rheumatoid arthritis...
Perforin-1
May affect: hemophagocytic lymphohistiocytosis; carcinoma; patellofemoral pain syndrome...
Farnesyl pyrophosphate synthase
May affect: disseminated intravascular coagulation; osteoporosis; chagas disease...
D(2) dopamine receptor
May affect: alcohol dependence; opiate dependence; schizophrenia...
Phospholipase A2, membrane associated
May affect: gas gangrene; atherosclerosis; toxic encephalopathy...
Neutrophil cytosol factor 1
May affect: williams-beuren syndrome; chronic granulomatous disease; hypertension...
G2/mitotic-specific cyclin-B1
May affect: cancer; polycystic ovary syndrome; adrenocortical carcinoma...
Matrix metalloproteinase-9
May affect: degenerative disc disease; kidney cancer; carcinoma...
Gamma-aminobutyric acid receptor subunit alpha-1
May affect: epilepsy; juvenile myoclonic epilepsy; carcinoma...
Indoleamine 2,3-dioxygenase 1
May affect: carcinoma; cancer; mental depression...
D-amino-acid oxidase
May affect: carcinoma; schizophrenia; bipolar disorder...
Serine/threonine-protein kinase B-raf
May affect: cardiomyopathy; cardiofaciocutaneous syndrome; intellectual disability...
Aminopeptidase N
May affect: lung cancer; kidney cancer; carcinoma...
15-hydroxyprostaglandin dehydrogenase [NAD(+)]
May affect: primary hypertrophic osteoarthropathy; cancer; intestinal benign neoplasm...
Arachidonate 15-lipoxygenase
May affect: cancer; atherosclerosis; asthma...
Platelet-derived growth factor receptor alpha
May affect: cancer; gastrointestinal stromal tumor; stomach cancer...
Protein kinase C alpha type
May affect: cancer; heart disease; carcinoma...
cAMP-dependent protein kinase catalytic subunit alpha
May affect: cushing's syndrome; carcinoma; carney complex...
Tyrosine-protein phosphatase non-receptor type 2
May affect: ulcerative colitis; celiac disease; motor neuron disease...
Neuronal acetylcholine receptor subunit beta-2
May affect: autosomal dominant nocturnal frontal lobe epilepsy; epilepsy; carcinoma...
X-box-binding protein 1
May affect: cancer; carcinoma; diabetes mellitus...
Vascular endothelial growth factor receptor 1
May affect: cardiovascular system disease; lung cancer; breast cancer...
Tyrosine-protein phosphatase non-receptor type 1
May affect: carcinoma; crohn's disease; diabetes mellitus...
Alpha-2B adrenergic receptor
May affect: epilepsy; carcinoma; hypertension...
3-oxo-5-alpha-steroid 4-dehydrogenase 1
May affect: prostate cancer; alcoholic intoxication, chronic; bipolar disorder...
Gamma-aminobutyric acid receptor subunit gamma-2
May affect: generalized epilepsy with febrile seizures plus; epilepsy; kidney cancer...
Sodium/hydrogen exchanger 1
May affect: neurodegenerative disease; kidney cancer; carcinoma...
Retinoic acid receptor RXR-alpha
May affect: carcinoma; cancer; keratoconus...
Cyclin-A2
May affect: cancer; liver cirrhosis, experimental; schizophrenia...
Arachidonate 5-lipoxygenase-activating protein
May affect: macular holes; asthma; cerebrovascular disease...
Muscarinic acetylcholine receptor M3
May affect: epilepsy; melanoma; carcinoma...
Integrin alpha-L
May affect: parkinson's disease; kidney cancer; carcinoma...
Amine oxidase [flavin-containing] A
May affect: brunner syndrome; intellectual disability; substance-related disorder...
Sphingosine 1-phosphate receptor 1
May affect: carcinoma; multiple sclerosis; lymphopenia...
fMet-Leu-Phe receptor
May affect: carcinoma; aggressive periodontitis; olecranon bursitis...
Cannabinoid receptor 1
May affect: obesity; attention deficit hyperactivity disorder; carcinoma...
Thromboxane A2 receptor
May affect: carcinoma; asthma; rhinitis...
Receptor tyrosine-protein kinase erbB-3
May affect: kidney cancer; carcinoma; type 1 diabetes mellitus...
D(4) dopamine receptor
May affect: opiate dependence; attention deficit hyperactivity disorder; schizophrenia...
Potassium voltage-gated channel subfamily A member 3
May affect: kidney cancer; carcinoma; panic disorder...
Acetylcholinesterase
May affect: carcinoma; type 2 diabetes mellitus; alzheimer's disease...
Fibroblast growth factor receptor 3
May affect: ladd syndrome; muenke syndrome; hypochondroplasia...
Nuclear receptor subfamily 4 group A member 1
May affect: carcinoma; cancer; fetal adenoma...
Neutrophil collagenase
May affect: melanoma; carcinoma; skin cancer...
Ribosomal protein S6 kinase beta-1
May affect: multiple sclerosis; cancer; lymphangioleiomyomatosis...
Tyrosine-protein kinase JAK1
May affect: immune system cancer; lymphoid leukemia; kidney cancer...
Chymase
May affect: mastocytosis; asthma; dermatitis...
Sodium-dependent noradrenaline transporter
May affect: lung cancer; carcinoma; attention deficit hyperactivity disorder...
G1/S-specific cyclin-D1
May affect: cancer; multiple myeloma; immune system cancer...
Corticotropin-releasing factor-binding protein
May affect: carcinoma; chronic kidney disease; alcohol dependence...
COUP transcription factor 2
May affect: carcinoma; congenital diaphragmatic hernia; autosomal dominant nonsyndromic deafness 15...
Endothelin receptor type B
May affect: hirschsprung's disease; waardenburg's syndrome; kidney cancer...
Thromboxane-A synthase
May affect: lymphoid leukemia; carcinoma; osteoarthritis...
G1/S-specific cyclin-E1
May affect: urinary bladder cancer; cancer; facial dermatosis...
Cyclin-dependent kinase 2
May affect: asthma; carcinoma; chronic obstructive pulmonary disease...
Histamine H2 receptor
May affect: carcinoma; rheumatoid arthritis; duodenal ulcer...
C-X-C chemokine receptor type 2
May affect: carcinoma; ulcerative colitis; cancer...
N-formyl peptide receptor 2
May affect: carcinoma; alzheimer's disease; secondary progressive multiple sclerosis...
Alpha-1D adrenergic receptor
May affect: carcinoma; schizophrenia; hyperekplexia...
Endothelin-1 receptor
May affect: intracranial aneurysm; dental caries; carcinoma...
Substance-P receptor
May affect: carcinoma; pain agnosia; asthma...
Platelet-activating factor receptor
May affect: carcinoma; pneumonia; liver cirrhosis, experimental...
Cathepsin S
May affect: carcinoma; cancer; atherosclerosis...
Neuropeptide Y receptor type 1
May affect: carcinoma; obesity; anxiety disorders...
Amine oxidase [flavin-containing] B
May affect: carcinoma; parkinson's disease; toxic encephalopathy...
Dipeptidyl peptidase 4
May affect: carcinoma; diabetes mellitus; hypoglycemia...
cAMP-specific 3',5'-cyclic phosphodiesterase 4A
May affect: carcinoma; chronic obstructive pulmonary disease; asthma...
Phosphatidylinositol 3-kinase regulatory subunit alpha
May affect: endometrial cancer; breast cancer; doid:2627...
5-hydroxytryptamine receptor 1D
May affect: migraine; obsessive-compulsive disorder; neurodegeneration with brain iron accumulation 5...
5-hydroxytryptamine receptor 1B
May affect: opiate dependence; carcinoma; migraine...
5-hydroxytryptamine receptor 2A
May affect: alcohol dependence; seasonal affective disorder; acquired metabolic disease...
5-hydroxytryptamine receptor 2C
May affect: carcinoma; schizophrenia; obsessive-compulsive disorder...
Gamma-aminobutyric acid receptor subunit beta-3
May affect: autism spectrum disorder; epilepsy; schizoaffective disorder...
Mitogen-activated protein kinase 1
May affect: multiple sclerosis; carcinoma; cancer...
Corticosteroid 11-beta-dehydrogenase isozyme 1
May affect: orofacial cleft; obesity; diabetes mellitus...
Adenosine receptor A2a
May affect: carcinoma; parkinson's disease; huntington's disease...
Adenosine receptor A2b
May affect: vascular disease; neoplasm metastasis; astrocytic glioma...
Neuromedin-K receptor
May affect: klinefelter's syndrome; kidney cancer; carcinoma...
Caspase-1
May affect: muckle-wells syndrome; vascular disease; cancer...
Nitric oxide synthase, endothelial
May affect: melanoma; carcinoma; hypertension...
Nitric oxide synthase, brain
May affect: attention deficit hyperactivity disorder; kidney cancer; carcinoma...
Non-receptor tyrosine-protein kinase TYK2
May affect: rheumatoid arthritis; crohn's disease; immune system cancer...
Wee1-like protein kinase
May affect: carcinoma; cancer; western equine encephalitis...
M-phase inducer phosphatase 1
May affect: carcinoma; cancer; ataxia telangiectasia...
M-phase inducer phosphatase 2
May affect: carcinoma; bipolar disorder; cancer...
Glycylpeptide N-tetradecanoyltransferase 1
May affect: carcinoma; thoracic outlet syndrome; lambert-eaton myasthenic syndrome...
Vasopressin V2 receptor
May affect: nephrogenic diabetes insipidus; diabetes insipidus; carcinoma...
Adenosine receptor A1
May affect: carcinoma; vascular disease; retinal ischemia...
Type-1 angiotensin II receptor
May affect: carcinoma; hypertension; kidney disease...
Neurotensin receptor type 1
May affect: carcinoma; cancer; hand, foot and mouth disease...
3-oxo-5-alpha-steroid 4-dehydrogenase 2
May affect: alcoholic intoxication, chronic; alopecia; cryptorchidism...
Sodium/glucose cotransporter 2
May affect: carcinoma; diabetes mellitus; hypoglycemia...
Gamma-aminobutyric acid receptor subunit alpha-5
May affect: schizoaffective disorder; kidney cancer; carcinoma...
Sodium-dependent serotonin transporter
May affect: alcohol dependence; carcinoma; major depressive disorder...
RAC-alpha serine/threonine-protein kinase
May affect: proteus syndrome; cancer; ovarian cancer...
RAC-beta serine/threonine-protein kinase
May affect: familial partial lipodystrophy; cancer; diabetes mellitus...
DNA dC->dU-editing enzyme APOBEC-3A
May affect: urinary bladder cancer; cancer; anogenital venereal wart...
Gastrin/cholecystokinin type B receptor
May affect: carcinoma; large intestine cancer; panic disorder...
Bombesin receptor subtype-3
May affect: carcinoma; obesity; medulloblastoma, large-cell...
Neuronal acetylcholine receptor subunit alpha-3
May affect: lung cancer; adenocarcinoma; substance-related disorder...
Somatostatin receptor type 3
May affect: carcinoma; adenoma; pituitary adenoma...
Cytochrome P450 2C19
May affect: melanoma; carcinoma; coronary artery disease...
Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial
May affect: active ulcerative colitis; gastric carcinoma; group 3 medulloblastoma...
Dual specificity protein kinase TTK
May affect: kidney cancer; carcinoma; cancer...
Gamma-aminobutyric acid receptor subunit alpha-3
May affect: carcinoma; mucopolysaccharidosis ii; reflex sympathetic dystrophy...
Mannose-6-phosphate isomerase
May affect: congenital disorder of glycosylation; protein-losing enteropathy; cutaneous leishmaniasis...
5-hydroxytryptamine receptor 7
May affect: carcinoma; migraine; irritable bowel syndrome...
Cannabinoid receptor 2
May affect: ovarian hyperstimulation syndrome; glycerol kinase deficiency; pain agnosia...
Corticotropin-releasing factor receptor 1
May affect: osteoporosis; carcinoma; chronic kidney disease...
Nitric oxide synthase, inducible
May affect: carcinoma; psoriasis; vascular disease...
Tyrosine-protein phosphatase non-receptor type 7
May affect: cutaneous lupus erythematosus; glioblastoma; interstitial cystitis...
Alpha-1A adrenergic receptor
May affect: multiple sclerosis; carcinoma; ureterolithiasis...
Prostaglandin G/H synthase 2
May affect: carcinoma; schizophrenia; cancer...
Histamine H1 receptor
May affect: carcinoma; allergic rhinitis; urticaria...
Alpha-1B adrenergic receptor
May affect: carcinoma; ureter carcinoma; ureterolithiasis...
Mu-type opioid receptor
May affect: alcohol dependence; opiate dependence; cardiovascular system disease...
Apelin receptor
May affect: lung cancer; carcinoma; hypertension...
D(3) dopamine receptor
May affect: alcohol dependence; opiate dependence; carcinoma...
Glucokinase
May affect: permanent neonatal diabetes mellitus; gestational diabetes; hyperinsulinemic hypoglycemia...
Vascular endothelial growth factor receptor 3
May affect: hereditary lymphedema; kidney cancer; carcinoma...
Vascular endothelial growth factor receptor 2
May affect: lung cancer; breast cancer; melanoma...
Neuronal acetylcholine receptor subunit alpha-7
May affect: schizophrenia; chromosome 15q13.3 microdeletion syndrome; autistic disorder...
Receptor-type tyrosine-protein kinase FLT3
May affect: cancer; immune system cancer; lymphoid leukemia...
TGF-beta receptor type-1
May affect: loeys-dietz syndrome; prostate cancer; thoracic aortic aneurysm...
Testosterone 17-beta-dehydrogenase 3
May affect: pseudohermaphroditism; carcinoma; androgen insensitivity syndrome...
Estradiol 17-beta-dehydrogenase 2
May affect: carcinoma; endometriosis; hypoactive sexual desire disorder...
Peroxisome proliferator-activated receptor gamma
May affect: familial partial lipodystrophy; diabetes mellitus; obesity...
Vasopressin V1a receptor
May affect: opiate dependence; carcinoma; autistic disorder...
Macrophage metalloelastase
May affect: spontaneous abortion; rheumatoid arthritis; colonic neoplasms...
Delta-type opioid receptor
May affect: opiate dependence; motor neuron disease; carcinoma...
Kappa-type opioid receptor
May affect: opiate dependence; carcinoma; large intestine cancer...
Nociceptin receptor
May affect: opiate dependence; pain agnosia; alcohol dependence...
Extracellular calcium-sensing receptor
May affect: epilepsy; cardiovascular system disease; melanoma...
Hepatocyte nuclear factor 4-alpha
May affect: hyperinsulinemic hypoglycemia; diabetes mellitus; carcinoma...
Mitogen-activated protein kinase kinase kinase 8
May affect: lung cancer; cancer; carcinoma...
Metabotropic glutamate receptor 5
May affect: attention deficit hyperactivity disorder; kidney cancer; substance-related disorder...
5-hydroxytryptamine receptor 2B
May affect: carcinoma; migraine; heart disease...
Signal transducer and activator of transcription 1-alpha/beta
May affect: herpes zoster; kidney cancer; carcinoma...
Aldo-keto reductase family 1 member C3
May affect: cancer; alcoholic intoxication, chronic; bipolar disorder...
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
May affect: lung cancer; cancer; ovarian cancer...
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
May affect: carcinoma; cancer; schizophrenia...
Serine/threonine-protein kinase mTOR
May affect: intellectual disability; epilepsy; globe disease...
Caspase-3
May affect: cancer; toxic encephalopathy; cerebrovascular disease...
Lysosomal Pro-X carboxypeptidase
May affect: carcinoma; c1 inhibitor deficiency; holoprosencephaly...
Huntingtin
May affect: intellectual disability; huntington's disease; neurodegenerative disease...
Endothelin-converting enzyme 1
May affect: hirschsprung's disease; carcinoma; amyotrophic lateral sclerosis...
Prostacyclin receptor
May affect: crohn's disease; hypertension; primary pulmonary hypertension...
Carbonic anhydrase 7
May affect: colorectal cancer; glaucoma; epilepsy...
Cathepsin K
May affect: pycnodysostosis; osteoporosis; osteopetrosis...
Tyrosine-protein kinase ZAP-70
May affect: severe combined immunodeficiency; kidney cancer; carcinoma...
Tyrosine-protein kinase SYK
May affect: prostate cancer; melanoma; multiple sclerosis...
Nicotinamide phosphoribosyltransferase
May affect: carcinoma; obesity; diabetes mellitus...
Neuronal acetylcholine receptor subunit alpha-4
May affect: autosomal dominant nocturnal frontal lobe epilepsy; epilepsy; carcinoma...
Collagenase 3
May affect: carcinoma; osteoarthritis; degenerative disc disease...
Mitogen-activated protein kinase 8
May affect: carcinoma; cancer; vascular disease...
Mitogen-activated protein kinase 9
May affect: carcinoma; cancer; vascular disease...
Solute carrier family 15 member 1
May affect: carcinoma; inflammatory bowel disease; hartnup disease...
5-hydroxytryptamine receptor 3A
May affect: carcinoma; irritable bowel syndrome; constipation...
Gamma-aminobutyric acid receptor subunit alpha-2
May affect: alcohol dependence; kidney cancer; carcinoma...
Gamma-aminobutyric acid receptor subunit beta-2
May affect: kidney cancer; carcinoma; liver cancer...
Glucagon receptor
May affect: diabetes mellitus; hyperglycemia; hypoglycemia...
Melatonin receptor type 1A
May affect: idiopathic scoliosis; frozen shoulder; retinal diseases...
ATP-sensitive inward rectifier potassium channel 1
May affect: bartter disease; carcinoma; hypokalemia...
Neuropeptides B/W receptor type 1
May affect: carcinoma...
Prolyl endopeptidase
May affect: carcinoma; hypotonia-cystinuria syndrome; amnestic disorder...
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
May affect: lung cancer; breast cancer; doid:2627...
MAP kinase-activated protein kinase 2
May affect: carcinoma; atypical teratoid / rhabdoid tumor; breast carcinoma...
Melatonin receptor type 1B
May affect: gestational diabetes; acquired metabolic disease; cardiovascular system disease...
Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha
May affect: carcinoma; pontocerebellar hypoplasia; acute myeloid leukemia...
Protein farnesyltransferase subunit beta
May affect: carcinoma; familial partial lipodystrophy...
Dual specificity protein kinase CLK1
May affect: carcinoma; acute myeloid leukemia; acute quadriplegic myopathy...
Glycogen synthase kinase-3 beta
May affect: alzheimer's disease; diabetes mellitus; kidney cancer...
Kallikrein-7
May affect: carcinoma; netherton syndrome; dermatitis...
5-hydroxytryptamine receptor 6
May affect: carcinoma; schizophrenia; alzheimer's disease...
Methionine aminopeptidase 2
May affect: carcinoma; acute quadriplegic myopathy; astrocytic glioma...
Cyclin-dependent kinase 9
May affect: takayasu's arteritis; vasculitis; cancer...
Dual specificity protein phosphatase 3
May affect: vaccinia; byssinosis; non-small cell lung carcinoma...
Probable global transcription activator SNF2L2
May affect: intellectual disability; hypotrichosis; kidney cancer...
C-C chemokine receptor type 3
May affect: celiac disease; alzheimer's disease; musculoskeletal system disease...
Ribosomal protein S6 kinase alpha-3
May affect: intellectual disability; coffin-lowry syndrome; kidney cancer...
Importin subunit alpha-1
May affect: carcinoma; nijmegen breakage syndrome; cancer...
Tyrosine-protein kinase JAK3
May affect: severe combined immunodeficiency; immune system cancer; lymphoid leukemia...
Kinesin-like protein KIF11
May affect: carcinoma; type 2 diabetes mellitus; microcephaly with or without chorioretinopathy, lymphedema, or mental retardation...
Serine/threonine-protein kinase PLK1
May affect: kidney cancer; carcinoma; cancer...
Geranylgeranyl transferase type-1 subunit beta
May affect: adult high grade glioma; astrocytoma; astrocytoma, pilocytic...
LIM domain kinase 1
May affect: williams-beuren syndrome; carcinoma; supravalvular aortic stenosis...
Mitogen-activated protein kinase 10
May affect: intellectual disability; epilepsy; carcinoma...
Ephrin type-B receptor 4
May affect: kidney cancer; carcinoma; cancer...
Tyrosine-protein phosphatase non-receptor type 5
May affect: carcinoma; nerve degeneration; schizophrenia...
Caspase-7
May affect: vitiligo; carcinoma; cancer...
Caspase-9
May affect: carcinoma; cancer; vascular disease...
Adenosine kinase
May affect: epilepsy; hypermethioninemia; adenosine deaminase deficiency...
P2X purinoceptor 3
May affect: carcinoma; interstitial cystitis; migraine...
Histone deacetylase 4
May affect: intellectual disability; carcinoma; obesity...
Beta-secretase 1
May affect: cardiovascular system disease; carcinoma; alzheimer's disease...
Regulator of G-protein signaling 8
May affect: spinocerebellar ataxia type 2; adult high grade glioma; astrocytic glioma...
Cell division control protein 42 homolog
May affect: intellectual disability; endometriosis; schizophrenia...
Ubiquitin-conjugating enzyme E2 N
May affect: cancer; embryo loss; astrocytic glioma...
Peptidyl-prolyl cis-trans isomerase FKBP1A
May affect: fibrodysplasia ossificans progressiva; malignant hyperthermia; reticulate acropigmentation of kitamura...
SUMO-conjugating enzyme UBC9
May affect: cancer; animal mammary neoplasms; mammary neoplasms, experimental...
P67874
No disease data available for this receptor.
Casein kinase II subunit alpha
May affect: intellectual disability; carcinoma; hemolytic anemia...
Cyclin-A1
May affect: carcinoma; cancer; papillomavirus infections...
Cyclin-dependent kinase 6
May affect: microcephaly; acquired metabolic disease; rheumatoid arthritis...
Cyclin-dependent-like kinase 5
May affect: lissencephaly; neurodegenerative disease; alzheimer's disease...
E3 ubiquitin-protein ligase Mdm2
May affect: cancer; carcinoma; lipoma...
Perilipin-5
May affect: obesity; fatty liver disease; ductal carcinoma in situ...
Sodium-dependent dopamine transporter
May affect: alcohol dependence; neurodegenerative disease; parkinson's disease...
Dihydroorotate dehydrogenase
May affect: carcinoma; nager acrofacial dysostosis; malaria...
Protein kinase C epsilon type
May affect: heart conduction disease; asthma; carcinoma...
Dual specificity mitogen-activated protein kinase kinase 1
May affect: cardiomyopathy; cardiofaciocutaneous syndrome; intellectual disability...
Angiopoietin-1 receptor
May affect: multiple cutaneous and mucosal venous malformations; glaucoma; breast cancer...
Peroxisome proliferator-activated receptor delta
May affect: carcinoma; obesity; diabetes mellitus...
Eukaryotic translation initiation factor 4 gamma 1
May affect: neurodegenerative disease; parkinson's disease; kidney cancer...
Protein kinase C theta type
May affect: rheumatoid arthritis; acquired metabolic disease; kidney cancer...
Focal adhesion kinase 1
May affect: kidney cancer; carcinoma; cancer...
Hormone-sensitive lipase
May affect: familial partial lipodystrophy; diabetes mellitus; obesity...
Glutamate receptor ionotropic, NMDA 1
May affect: intellectual disability; carcinoma; schizophrenia...
Protein kinase C delta type
May affect: common variable immunodeficiency; cancer; carcinoma...
Tyrosine-protein phosphatase non-receptor type 11
May affect: leopard syndrome; noonan syndrome; immune system cancer...
Tyrosine-protein kinase BTK
May affect: isolated growth hormone deficiency; bruton-type agammaglobulinemia; carcinoma...
Tyrosine-protein kinase receptor TYRO3
May affect: carcinoma; enamel erosion; status epilepticus...
DNA repair protein RAD51 homolog 1
May affect: fanconi anemia; breast cancer; cancer...
cAMP-specific 3',5'-cyclic phosphodiesterase 4B
May affect: lymphoid leukemia; heart disease; carcinoma...
Bcl-2-like protein 1
May affect: cancer; vascular disease; neurodegenerative disease...
Induced myeloid leukemia cell differentiation protein Mcl-1
May affect: cancer; barrett esophagus; leishmaniasis...
Peroxisome proliferator-activated receptor alpha
May affect: lipid metabolism disorder; diabetes mellitus; obesity...
Activated CDC42 kinase 1
May affect: carcinoma; cancer; liver neoplasms...
Tyrosine-protein kinase ITK/TSK
May affect: lung cancer; kidney cancer; carcinoma...
Potassium voltage-gated channel subfamily H member 2
May affect: familial atrial fibrillation; short qt syndrome; long qt syndrome 1...
Prolyl endopeptidase FAP
May affect: vitiligo; carcinoma; crohn's disease...
Acetyl-CoA carboxylase 1
May affect: endometrial cancer; breast cancer; kidney cancer...
Oxysterols receptor LXR-alpha
May affect: metabolic syndrome x; carcinoma; atherosclerosis...
Glutamate receptor ionotropic, NMDA 2B
May affect: autism spectrum disorder; intellectual disability; epilepsy...
Metabotropic glutamate receptor 1
May affect: neurodegenerative disease; kidney cancer; carcinoma...
Prostaglandin D2 receptor
May affect: asthma; carcinoma; autosomal dominant nonsyndromic deafness 17...
Steroidogenic factor 1
May affect: 46 xy gonadal dysgenesis; premature ovarian failure; hypogonadism...
Phospholipase D1
May affect: kidney cancer; carcinoma; cardiomegaly...
Rho-associated protein kinase 1
May affect: kidney cancer; carcinoma; cancer...
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
May affect: meibomian cyst; post-traumatic stress disorder; cancer...
Histone deacetylase 1
May affect: carcinoma; cancer; squamous cell carcinoma...
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
May affect: autism spectrum disorder; intellectual disability; metabolic syndrome x...
Voltage-dependent L-type calcium channel subunit alpha-1C
May affect: brugada syndrome; timothy syndrome; long qt syndrome...
Inhibitor of nuclear factor kappa-B kinase subunit epsilon
May affect: carcinoma; unipolar depression; major depressive disorder...
Metabotropic glutamate receptor 2
May affect: carcinoma; schizophrenia; cocaine dependence...
Eukaryotic translation initiation factor 4H
May affect: williams-beuren syndrome; multiple myeloma; ovarian cancer...
Cyclin-dependent kinase 5 activator 1
May affect: brain diseases; cognition disorders; nerve degeneration...
Receptor tyrosine-protein kinase erbB-4
May affect: polycystic ovary syndrome; neurodegenerative disease; amyotrophic lateral sclerosis...
Ribosomal protein S6 kinase alpha-2
May affect: dental caries; kidney cancer; carcinoma...
Nuclear receptor coactivator 2
May affect: lung cancer; kidney cancer; carcinoma...
Nuclear receptor coactivator 1
May affect: cancer; kidney cancer; carcinoma...
Gamma-aminobutyric acid receptor subunit alpha-6
May affect: breast cancer; doid:2627; kidney cancer...
Mitogen-activated protein kinase 14
May affect: carcinoma; cancer; vascular disease...
Vesicular acetylcholine transporter
May affect: congenital myasthenic syndrome; kidney cancer; carcinoma...
Hypoxia-inducible factor 1-alpha
May affect: carcinoma; cancer; vascular disease...
Glutaminyl-peptide cyclotransferase
May affect: carcinoma; lung cancer; alzheimer's disease...
Carbonic anhydrase 9
May affect: carcinoma; cancer; oxyphilic adenoma...
Q1HVG2
No disease data available for this receptor.
Q4U254
No disease data available for this receptor.
Leucine-rich repeat serine/threonine-protein kinase 2
May affect: neurodegenerative disease; parkinson's disease; crohn's disease...
Opioid growth factor receptor-like protein 1
May affect: carcinoma; adrenocortical carcinoma; atypical teratoid / rhabdoid tumor...
Dipeptidyl peptidase 8
May affect: kidney cancer; carcinoma; diabetes mellitus...
5-hydroxytryptamine receptor 3D
May affect: carcinoma; irritable bowel syndrome; primary angle-closure glaucoma...
Q72547
No disease data available for this receptor.
Q72874
No disease data available for this receptor.
Q7ZJM1
No disease data available for this receptor.
Dipeptidyl peptidase 9
May affect: interstitial lung disease; diabetes mellitus; idiopathic pulmonary fibrosis...
Serine/threonine-protein kinase pim-3
May affect: cancer...
NAD-dependent protein deacetylase sirtuin-2
May affect: neurodegenerative disease; cancer; diabetes mellitus...
Transient receptor potential cation channel subfamily V member 1
May affect: carcinoma; pain agnosia; migraine...
Mucolipin-3
May affect: kidney cancer; carcinoma; gangliosidosis...
G-protein coupled bile acid receptor 1
May affect: cholestasis; obesity; diabetes mellitus...
G2/mitotic-specific cyclin-B3
May affect: kidney cancer; carcinoma; ewing sarcoma...
5-hydroxytryptamine receptor 3C
May affect: carcinoma; primary angle-closure glaucoma; autistic disorder...
Estrogen receptor beta
May affect: carcinoma; cancer; endometriosis...
Histone deacetylase 2
May affect: carcinoma; chronic obstructive pulmonary disease; cancer...
CREB-binding protein
May affect: rubinstein-taybi syndrome; immune system cancer; lymphoid leukemia...
NAD-dependent protein deacetylase sirtuin-1
May affect: carcinoma; cancer; diabetes mellitus...
Aurora kinase B
May affect: cancer; iga glomerulonephritis; stomach neoplasms...
Sentrin-specific protease 8
May affect: dengue disease; yellow fever; exanthem...
Diacylglycerol O-acyltransferase 2
May affect: carcinoma; fatty liver disease; obesity...
Trace amine-associated receptor 1
May affect: lung cancer; carcinoma; schizophrenia...
Sphingosine 1-phosphate receptor 3
May affect: carcinoma; multiple sclerosis; adult high grade glioma...
Monoglyceride lipase
May affect: pain agnosia; obesity; alcoholic intoxication, chronic...
Melanin-concentrating hormone receptor 1
May affect: carcinoma; obesity; hypotrichosis 1...
Sigma non-opioid intracellular receptor 1
May affect: neurodegenerative disease; amyotrophic lateral sclerosis; schizophrenia...
Equilibrative nucleoside transporter 1
May affect: carcinoma; cancer; gestational diabetes...
Endothelial PAS domain-containing protein 1
May affect: primary polycythemia; kidney cancer; carcinoma...
MAP kinase-interacting serine/threonine-protein kinase 1
May affect: carcinoma; cancer; substance-related disorders...
Histone deacetylase 8
May affect: intellectual disability; cornelia de lange syndrome; obesity...
Serine/threonine-protein kinase 33
May affect: acquired metabolic disease; carcinoma; obesity...
Sentrin-specific protease 6
May affect: carcinoma; sarcocystosis; waterhouse-friderichsen syndrome...
Egl nine homolog 1
May affect: primary polycythemia; carcinoma; polycythemia...
Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1
May affect: astrocytoma, pilocytic; glioblastoma; osteosarcoma...
Sphingosine 1-phosphate receptor 5
May affect: carcinoma; multiple sclerosis; lymphopenia...
P2Y purinoceptor 12
May affect: carcinoma; coronary artery disease; cerebrovascular disease...
Histamine H4 receptor
May affect: carcinoma; asthma; dermatitis...
MAP kinase-interacting serine/threonine-protein kinase 2
May affect: carcinoma; astrocytoma; glioblastoma...
DNA dC->dU-editing enzyme APOBEC-3G
May affect: human immunodeficiency virus infectious disease; hepatitis b; cancer...
G-protein coupled receptor 35
May affect: carcinoma; gastrointestinal system disease; ulcerative colitis...
Interleukin-1 receptor-associated kinase 4
May affect: carcinoma; meningitis; adenosine deaminase deficiency...
Serine/threonine-protein kinase pim-2
May affect: cancer; carcinoma; kabuki syndrome...
Q9QR71
No disease data available for this receptor.
SUMO-activating enzyme subunit 1
May affect: multiple sclerosis; adrenocortical carcinoma; astrocytic glioma...
Histone deacetylase 6
May affect: carcinoma; cancer; neurodegenerative disease...
Protein DBF4 homolog A
May affect: adrenocortical carcinoma; adult high grade glioma; astrocytoma...
Dipeptidyl peptidase 2
May affect: carcinoma; deafness dystonia syndrome; liver cirrhosis, experimental...
ALK tyrosine kinase receptor
May affect: lung cancer; cancer; neuroblastoma...
A disintegrin and metalloproteinase with thrombospondin motifs 5
May affect: kidney cancer; carcinoma; osteoarthritis...
ATP-binding cassette sub-family G member 2
May affect: gout; dental caries; carcinoma...
Q9WKE8
No disease data available for this receptor.
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
May affect: acquired metabolic disease; conduct disorder; kidney cancer...
Nucleotide-binding oligomerization domain-containing protein 1
May affect: carcinoma; crohn's disease; blau syndrome...
RAC-gamma serine/threonine-protein kinase
May affect: heart conduction disease; carcinoma; epilepsy...
G-protein coupled receptor 55
May affect: carcinoma; osteosarcoma; neoplasms...
Sodium- and chloride-dependent glycine transporter 2
May affect: hyperekplexia; melanoma; kidney cancer...
5'-AMP-activated protein kinase subunit beta-1
May affect: stomach neoplasms; gaucher disease type 1; group 4 medulloblastoma...
Cysteine protease ATG4B
May affect: carcinoma; breast carcinoma; osteosarcoma...
Histamine H3 receptor
May affect: narcolepsy; attention deficit hyperactivity disorder; schizophrenia...
Photoreceptor-specific nuclear receptor
May affect: glaucoma; conductive hearing loss; sensorineural hearing loss (disorder)...
Endothelial lipase
May affect: carcinoma; atherosclerosis; gastric leiomyoma...
Prostaglandin D2 receptor 2
May affect: asthma; allergic rhinitis; atopic dermatitis...
Beta-secretase 2
May affect: carcinoma; alzheimer's disease; down syndrome...
Nuclear receptor coactivator 3
May affect: osteoarthritis; leukemia; kidney cancer...
Orexin type-2 receptor isoform 1
No disease data available for this receptor.