matter.farm

Computer-generated molecule database for public drug discovery. About this project.

These compounds may interact with:

Orexin receptor type 1

Potentially involved in: narcolepsy; seasonal affective disorder; pain agnosia; cannabis dependence; mental depression; depressive disorder; schizophrenia; substance withdrawal syndrome; cocaine-related disorders; mood disorders; insomnia

Disease data sourced from Pharos.

Antagonist

FORMULA:C27H42N4O4

SMILES: Cc1cccc(C)c1C(=O)N1CCOCCNCCOCCO[C@](C)([C@H](C)n2c(C)cnc2C)C1

BIRTHDAY: 2018-12-01T14:11:38.503016
ATC: N02B
- NERVOUS SYSTEM
- ANALGESICS
- OTHER ANALGESICS AND ANTIPYRETICS
Synthesis Plan
FORMULA:C22H25N7O

SMILES: Cc1ccc(-n2nccn2)c(C(=O)N2C[C@@H]3CN(c4nc(C)cc(C)n4)C[C@H]3C2)c1

BIRTHDAY: 2018-12-01T14:11:38.513452
ATC: C01B
- CARDIOVASCULAR SYSTEM
- CARDIAC THERAPY
- ANTIARRHYTHMICS, CLASS I AND III
Synthesis Plan
FORMULA:C23H21ClN6O2

SMILES: Cc1ccc(-c2nc([C@H]3CCN(C(=O)c4ccc(-n5nccn5)c(C)c4)C3)no2)c(Cl)c1

BIRTHDAY: 2018-12-01T14:11:38.524563
ATC: S01X
- SENSORY ORGANS
- OPHTHALMOLOGICALS
- OTHER OPHTHALMOLOGICALS
Synthesis Plan
FORMULA:C26H24FN7O

SMILES: O=C(c1ccc(F)c(-n2nccn2)c1)N1CCC[C@]12CCCN2c1cncnc1-c1ccccc1

BIRTHDAY: 2018-12-01T14:11:38.547509
ATC: C02A
- CARDIOVASCULAR SYSTEM
- ANTIHYPERTENSIVES
- ANTIADRENERGIC AGENTS, CENTRALLY ACTING
Synthesis Plan
FORMULA:C26H24FN7O

SMILES: O=C(c1ccc(F)c(-n2nccn2)c1)N1CCC[C@]12CCCN2c1cnc(-c2ccccc2)nc1

BIRTHDAY: 2018-12-01T14:11:38.559804
ATC: N05A
- NERVOUS SYSTEM
- PSYCHOLEPTICS
- ANTIPSYCHOTICS
Synthesis Plan
FORMULA:C23H21ClN6O2

SMILES: Cc1ccc(-n2nccn2)c(C(=O)N2CCC[C@@H]2c2nc(-c3cccc(Cl)c3C)no2)c1

BIRTHDAY: 2018-12-01T14:11:38.581075
ATC: C08D
- CARDIOVASCULAR SYSTEM
- CALCIUM CHANNEL BLOCKERS
- SELECTIVE CALCIUM CHANNEL BLOCKERS WITH DIRECT CARDIAC EFFECTS
Synthesis Plan
FORMULA:C23H26FNO

SMILES: CCN(C(=O)C1CC1)[C@@]12C[C@H]3[C@H]4C[C@H]5[C@@H](C[C@H]1[C@@]35c1ccccc1F)[C@H]42

BIRTHDAY: 2018-12-01T14:11:38.589557
ATC: N07X
- NERVOUS SYSTEM
- OTHER NERVOUS SYSTEM DRUGS
- OTHER NERVOUS SYSTEM DRUGS
Synthesis Plan
FORMULA:C23H21ClN6O2

SMILES: Cc1ccc(-c2noc([C@@H]3CCN(C(=O)c4cccc(-n5nccn5)c4C)C3)n2)cc1Cl

BIRTHDAY: 2018-12-01T14:11:38.611351
ATC: N07C
- NERVOUS SYSTEM
- OTHER NERVOUS SYSTEM DRUGS
- ANTIVERTIGO PREPARATIONS
Synthesis Plan
FORMULA:C23H21ClN6O2

SMILES: Cc1ccc(-c2nc([C@H]3CCN(C(=O)c4cccc(-n5nccn5)c4C)C3)no2)cc1Cl

BIRTHDAY: 2018-12-01T14:11:38.621648
ATC: N07C
- NERVOUS SYSTEM
- OTHER NERVOUS SYSTEM DRUGS
- ANTIVERTIGO PREPARATIONS
Synthesis Plan
FORMULA:C23H21ClN6O2

SMILES: Cc1cc(C(=O)N2CC[C@@H](c3noc(-c4c(C)cccc4Cl)n3)C2)ccc1-n1nccn1

BIRTHDAY: 2018-12-01T14:11:38.632326
ATC: A14A
- ALIMENTARY TRACT AND METABOLISM
- ANABOLIC AGENTS FOR SYSTEMIC USE
- ANABOLIC STEROIDS
Synthesis Plan
FORMULA:C25H22FN7O

SMILES: O=C(c1cc(F)ccc1-n1nccn1)N1C[C@@H]2CN(c3nccc(-c4ccccc4)n3)C[C@H]2C1

BIRTHDAY: 2018-12-01T14:11:38.643236
ATC: C01B
- CARDIOVASCULAR SYSTEM
- CARDIAC THERAPY
- ANTIARRHYTHMICS, CLASS I AND III
Synthesis Plan
FORMULA:C24H28N6O2

SMILES: COc1ccc(C(=O)N2C[C@@H]3CN(c4nc(C)c(C)c(C)n4)C[C@@H]3C2)c(-c2ccn[nH]2)c1

BIRTHDAY: 2018-12-01T14:11:38.665792
ATC: A10B
- ALIMENTARY TRACT AND METABOLISM
- DRUGS USED IN DIABETES
- BLOOD GLUCOSE LOWERING DRUGS, EXCL. INSULINS
Synthesis Plan
FORMULA:C26H24FN7O

SMILES: O=C(c1ccc(F)c(-n2nccn2)c1)N1CCC[C@@]12CCCN2c1cncnc1-c1ccccc1

BIRTHDAY: 2018-12-25T02:03:41.335745
ATC: C02A
- CARDIOVASCULAR SYSTEM
- ANTIHYPERTENSIVES
- ANTIADRENERGIC AGENTS, CENTRALLY ACTING
Synthesis Plan
FORMULA:C23H27N7O2

SMILES: COc1c(C(=O)N2CCC[C@]23CCCN3c2c(C)ncnc2C)cccc1-n1nccn1

BIRTHDAY: 2018-12-25T02:03:41.347283
ATC: M01A
- MUSCULO-SKELETAL SYSTEM
- ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS
- ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS
Synthesis Plan
FORMULA:C23H21ClN6O2

SMILES: Cc1ccc(C(=O)N2CCC[C@@H]2c2nc(-c3c(C)cccc3Cl)no2)c(-n2nccn2)c1

BIRTHDAY: 2018-12-25T02:03:41.358126
ATC: C01B
- CARDIOVASCULAR SYSTEM
- CARDIAC THERAPY
- ANTIARRHYTHMICS, CLASS I AND III
Synthesis Plan
FORMULA:C12H14N2

SMILES: Cc1ccc(C2=NNCC=CC2)cc1

BIRTHDAY: 2018-12-25T02:03:41.363820
ATC: M01A
- MUSCULO-SKELETAL SYSTEM
- ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS
- ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS
Synthesis Plan
FORMULA:C23H27N7O

SMILES: Cc1ccc(C(=O)N2CCC[C@]23CCCN3c2c(C)ncnc2C)cc1-n1nccn1

BIRTHDAY: 2018-12-25T02:03:41.374622
ATC: N05A
- NERVOUS SYSTEM
- PSYCHOLEPTICS
- ANTIPSYCHOTICS
Synthesis Plan
FORMULA:C23H21ClN6O2

SMILES: Cc1ccc(-c2nc([C@@H]3CCN(C(=O)c4cccc(-n5nccn5)c4C)C3)no2)cc1Cl

BIRTHDAY: 2018-12-25T02:03:41.384908
ATC: N07C
- NERVOUS SYSTEM
- OTHER NERVOUS SYSTEM DRUGS
- ANTIVERTIGO PREPARATIONS
Synthesis Plan
FORMULA:C24H24N6O3

SMILES: COc1ccc(-c2noc([C@@H]3CCN(C(=O)c4cccc(-n5nccn5)c4C)C3)n2)cc1C

BIRTHDAY: 2018-12-25T02:03:41.395497
ATC: C01B
- CARDIOVASCULAR SYSTEM
- CARDIAC THERAPY
- ANTIARRHYTHMICS, CLASS I AND III
Synthesis Plan
FORMULA:C23H21ClN6O2

SMILES: Cc1ccc(-c2noc([C@H]3CCN(C(=O)c4ccc(C)c(-n5nccn5)c4)C3)n2)cc1Cl

BIRTHDAY: 2018-12-25T02:03:41.406228
ATC: N07C
- NERVOUS SYSTEM
- OTHER NERVOUS SYSTEM DRUGS
- ANTIVERTIGO PREPARATIONS
Synthesis Plan
FORMULA:C25H22FN7O

SMILES: O=C(c1cc(F)ccc1-n1nccn1)N1C[C@@H]2CN(c3nccc(-c4ccccc4)n3)C[C@@H]2C1

BIRTHDAY: 2018-12-25T02:03:41.417091
ATC: C01B
- CARDIOVASCULAR SYSTEM
- CARDIAC THERAPY
- ANTIARRHYTHMICS, CLASS I AND III
Synthesis Plan
FORMULA:C24H28N6O2

SMILES: COc1ccc(C(=O)N2C[C@H]3CN(c4nc(C)c(C)c(C)n4)C[C@@H]3C2)c(-c2ccn[nH]2)c1

BIRTHDAY: 2018-12-25T02:03:41.427259
ATC: A10B
- ALIMENTARY TRACT AND METABOLISM
- DRUGS USED IN DIABETES
- BLOOD GLUCOSE LOWERING DRUGS, EXCL. INSULINS
Synthesis Plan
FORMULA:C24H28N6O2

SMILES: COc1cc(C(=O)N2CCC[C@]23CCCN3c2c(C)ncnc2C)cc(-c2cn[nH]c2)c1

BIRTHDAY: 2018-12-25T02:03:41.438203
ATC: M01A
- MUSCULO-SKELETAL SYSTEM
- ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS
- ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS
Synthesis Plan
FORMULA:C23H27N7O

SMILES: Cc1ccc(C(=O)N2CCC[C@@]23CCCN3c2c(C)ncnc2C)cc1-n1nccn1

BIRTHDAY: 2018-12-25T02:03:41.469862
ATC: N05A
- NERVOUS SYSTEM
- PSYCHOLEPTICS
- ANTIPSYCHOTICS
Synthesis Plan
FORMULA:C22H25N7O

SMILES: Cc1ccc(C(=O)N2C[C@@H]3CN(c4ncc(C)c(C)n4)C[C@@H]3C2)c(-n2nccn2)c1

BIRTHDAY: 2018-12-25T02:03:41.501052
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C28H25FN6O

SMILES: O=C(c1cc(F)cc(-c2cncnc2)c1)N1CCC[C@@]12CCCN2c1cncnc1-c1ccccc1

BIRTHDAY: 2018-12-03T02:39:46.931938
ATC: M01A
- MUSCULO-SKELETAL SYSTEM
- ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS
- ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS
Synthesis Plan
FORMULA:C23H21ClN6O2

SMILES: Cc1ccc(-c2nc([C@@H]3CCN(C(=O)c4ccc(-n5nccn5)c(C)c4)C3)no2)cc1Cl

BIRTHDAY: 2018-12-03T02:39:46.942539
ATC: V08A
- VARIOUS
- CONTRAST MEDIA
- X-RAY CONTRAST MEDIA, IODINATED
Synthesis Plan
FORMULA:C23H27N7O

SMILES: Cc1ncnc(C)c1N1CCC[C@]12CCCN2C(=O)c1cccc(-n2nccn2)c1C

BIRTHDAY: 2018-12-03T02:39:46.964651
ATC: M01A
- MUSCULO-SKELETAL SYSTEM
- ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS
- ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS
Synthesis Plan
FORMULA:C25H27N5OS2

SMILES: O=C1Nc2ccccc2CNCCNC[C@H]2CSC(=N2)c2nc1sc2CCc1ccccc1

BIRTHDAY: 2018-12-03T02:39:46.986160
ATC: G03B
- GENITO URINARY SYSTEM AND SEX HORMONES
- SEX HORMONES AND MODULATORS OF THE GENITAL SYSTEM
- ANDROGENS
Synthesis Plan
FORMULA:C24H29N5O2

SMILES: COc1ccc(C(=O)N2CCC[C@@]23CCCN3c2ncnc3c2[C@H]2CNC[C@@H]3C2)cc1

BIRTHDAY: 2018-12-03T02:39:47.029771
ATC: N05C
- NERVOUS SYSTEM
- PSYCHOLEPTICS
- HYPNOTICS AND SEDATIVES
Synthesis Plan
FORMULA:C23H26N6O2

SMILES: COc1ccc(C(=O)N2C[C@@H]3CN(c4nc(C)cc(C)n4)C[C@@H]3C2)c(-c2cc[nH]n2)c1

BIRTHDAY: 2018-12-03T02:39:47.040005
ATC: G04C
- GENITO URINARY SYSTEM AND SEX HORMONES
- UROLOGICALS
- DRUGS USED IN BENIGN PROSTATIC HYPERTROPHY
Synthesis Plan
FORMULA:C23H27N7O2

SMILES: COc1c(C(=O)N2CCC[C@@]23CCCN3c2c(C)ncnc2C)cccc1-n1nccn1

BIRTHDAY: 2018-12-03T02:39:47.083306
ATC: M01A
- MUSCULO-SKELETAL SYSTEM
- ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS
- ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS
Synthesis Plan
FORMULA:C23H21ClN6O2

SMILES: Cc1ccc(-c2nc([C@@H]3CCN(C(=O)c4cccc(-n5nccn5)c4C)C3)no2)c(Cl)c1

BIRTHDAY: 2018-12-03T02:39:47.105373
ATC: C02A
- CARDIOVASCULAR SYSTEM
- ANTIHYPERTENSIVES
- ANTIADRENERGIC AGENTS, CENTRALLY ACTING
Synthesis Plan
FORMULA:C23H21FN6O2

SMILES: Cc1ccc(-n2nccn2)c(C(=O)N2CCC[C@@H]2c2nc(-c3cccc(F)c3C)no2)c1

BIRTHDAY: 2018-11-30T03:41:42.693035
ATC: C01B
- CARDIOVASCULAR SYSTEM
- CARDIAC THERAPY
- ANTIARRHYTHMICS, CLASS I AND III
Synthesis plan pending
FORMULA:C26H24FN7O

SMILES: O=C(c1cc(F)cc(-n2nccn2)c1)N1CCC[C@@]12CCCN2c1ncncc1-c1ccccc1

BIRTHDAY: 2018-11-30T03:41:42.716499
ATC: C08D
- CARDIOVASCULAR SYSTEM
- CALCIUM CHANNEL BLOCKERS
- SELECTIVE CALCIUM CHANNEL BLOCKERS WITH DIRECT CARDIAC EFFECTS
Synthesis plan pending
FORMULA:C25H22FN7O

SMILES: O=C(c1ccc(F)cc1-n1nccn1)N1C[C@@H]2CN(c3nccc(-c4ccccc4)n3)C[C@@H]2C1

BIRTHDAY: 2018-11-30T03:41:42.738195
ATC: C10A
- CARDIOVASCULAR SYSTEM
- LIPID MODIFYING AGENTS
- LIPID MODIFYING AGENTS, PLAIN
Synthesis plan pending
FORMULA:C34H35N7O3

SMILES: Cc1c(C(=O)N2CC[C@@H]([C@H]3c4cc5ccc4N=CN3CCC(=O)CNCCc3cccc(c3)O5)C2)cccc1-n1nccn1

BIRTHDAY: 2018-11-30T03:41:42.751340
ATC: L01B
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- ANTIMETABOLITES
Synthesis plan pending
FORMULA:C26H24FN7O

SMILES: O=C(c1ccc(F)c(-n2nccn2)c1)N1CCC[C@@]12CCCN2c1cnc(-c2ccccc2)nc1

BIRTHDAY: 2018-11-30T03:41:42.763651
ATC: N05A
- NERVOUS SYSTEM
- PSYCHOLEPTICS
- ANTIPSYCHOTICS
Synthesis plan pending
FORMULA:C23H33N

SMILES: Cc1ccc([C@@]23C[C@@H]4C[C@H]2N2CC[C@H]3C(C)(C)[C@H]2[C@H]4C)c(C)c1C

BIRTHDAY: 2018-11-30T03:41:42.781389
ATC: A11H
- ALIMENTARY TRACT AND METABOLISM
- VITAMINS
- OTHER PLAIN VITAMIN PREPARATIONS
Synthesis plan pending
FORMULA:C24H24N6O3

SMILES: COc1ccc(C)cc1-c1nc([C@H]2CCCN2C(=O)c2cc(C)ccc2-n2nccn2)no1

BIRTHDAY: 2018-11-30T03:41:42.835212
ATC: C05A
- CARDIOVASCULAR SYSTEM
- VASOPROTECTIVES
- AGENTS FOR TREATMENT OF HEMORRHOIDS AND ANAL FISSURES FOR TOPICAL USE
Synthesis plan pending
FORMULA:C23H21ClN6O2

SMILES: Cc1ccc(-c2noc([C@H]3CCN(C(=O)c4cccc(-n5nccn5)c4C)C3)n2)cc1Cl

BIRTHDAY: 2018-11-30T03:41:42.845659
ATC: N07C
- NERVOUS SYSTEM
- OTHER NERVOUS SYSTEM DRUGS
- ANTIVERTIGO PREPARATIONS
Synthesis plan pending
FORMULA:C25H30N6O2

SMILES: COc1cc(C(=O)N2CCC[C@@]23CCCN3c2c(C)nc(C)nc2C)cc(-c2cn[nH]c2)c1

BIRTHDAY: 2018-11-30T03:41:42.867303
ATC: M01A
- MUSCULO-SKELETAL SYSTEM
- ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS
- ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS
Synthesis plan pending
FORMULA:C24H30N6O2S2

SMILES: Cc1ccc(C(=O)N2CC[C@]3(CNCCNC[C@H]4CSC(=N4)c4csc(n4)CNC3=O)C2)cc1

BIRTHDAY: 2018-11-19T08:13:05.466051
ATC: P02C
- ANTIPARASITIC PRODUCTS, INSECTICIDES AND REPELLENTS
- ANTHELMINTICS
- ANTINEMATODAL AGENTS
Synthesis plan pending
FORMULA:C23H21FN6O2

SMILES: Cc1ccc(-c2nc([C@H]3CCN(C(=O)c4cccc(-n5nccn5)c4C)C3)no2)cc1F

BIRTHDAY: 2018-11-19T08:13:05.487705
ATC: J05A
- ANTIINFECTIVES FOR SYSTEMIC USE
- ANTIVIRALS FOR SYSTEMIC USE
- DIRECT ACTING ANTIVIRALS
Synthesis plan pending
FORMULA:C23H21ClN6O2

SMILES: Cc1ccc(C(=O)N2CCC[C@@H]2c2nc(-c3cccc(Cl)c3C)no2)c(-n2nccn2)c1

BIRTHDAY: 2018-11-19T08:13:05.498700
ATC: J01C
- ANTIINFECTIVES FOR SYSTEMIC USE
- ANTIBACTERIALS FOR SYSTEMIC USE
- BETA-LACTAM ANTIBACTERIALS, PENICILLINS
Synthesis plan pending
FORMULA:C23H25N5O2

SMILES: Cc1c(C(=O)N2CC[C@@H](C(=O)N3C[C@@H]4C=CC=C[C@H]4C3)C2)cccc1-n1nccn1

BIRTHDAY: 2018-11-19T08:13:05.508582
ATC: J05A
- ANTIINFECTIVES FOR SYSTEMIC USE
- ANTIVIRALS FOR SYSTEMIC USE
- DIRECT ACTING ANTIVIRALS
Synthesis plan pending
FORMULA:C23H27N7O

SMILES: Cc1cc(C(=O)N2CCC[C@@]23CCCN3c2c(C)ncnc2C)ccc1-n1nccn1

BIRTHDAY: 2018-11-19T08:13:05.520308
ATC: C03X
- CARDIOVASCULAR SYSTEM
- DIURETICS
- OTHER DIURETICS
Synthesis plan pending
FORMULA:C25H30N6O2

SMILES: COc1cc(C(=O)N2CC[C@@]3(CCCN3c3c(C)nc(C)nc3C)C2)cc(-c2ccn[nH]2)c1

BIRTHDAY: 2018-11-19T08:13:05.553925
ATC: J01M
- ANTIINFECTIVES FOR SYSTEMIC USE
- ANTIBACTERIALS FOR SYSTEMIC USE
- QUINOLONE ANTIBACTERIALS
Synthesis plan pending
FORMULA:C22H25N7O

SMILES: Cc1ncc(N2C[C@H]3CN(C(=O)c4cccc(C)c4-n4nccn4)C[C@H]3C2)c(C)n1

BIRTHDAY: 2018-11-19T08:13:05.563865
ATC: S01A
- SENSORY ORGANS
- OPHTHALMOLOGICALS
- ANTIINFECTIVES
Synthesis plan pending
FORMULA:C23H21ClN6O2

SMILES: Cc1cc(-n2nccn2)ccc1C(=O)N1CCC[C@H]1c1noc(-c2c(C)cccc2Cl)n1

BIRTHDAY: 2018-11-19T08:13:05.575179
ATC: S01F
- SENSORY ORGANS
- OPHTHALMOLOGICALS
- MYDRIATICS AND CYCLOPLEGICS
Synthesis plan pending
FORMULA:C23H26N6O2

SMILES: COc1ccc(C(=O)N2C[C@@H]3CN(c4nc(C)cc(C)n4)C[C@H]3C2)c(-c2cc[nH]n2)c1

BIRTHDAY: 2018-11-19T08:13:05.585998
ATC: G04C
- GENITO URINARY SYSTEM AND SEX HORMONES
- UROLOGICALS
- DRUGS USED IN BENIGN PROSTATIC HYPERTROPHY
Synthesis plan pending
FORMULA:C27H33N5O3

SMILES: COc1ccc(C(=O)N2C[C@@H]3CN(c4nc(C)c5c(n4)C[C@H]4CCC[C@H]5N4C(C)=O)C[C@H]3C2)cc1

BIRTHDAY: 2018-11-19T08:13:05.619140
ATC: D01A
- DERMATOLOGICALS
- ANTIFUNGALS FOR DERMATOLOGICAL USE
- ANTIFUNGALS FOR TOPICAL USE
Synthesis plan pending
FORMULA:C27H30N4O2

SMILES: Cc1cccc(C(=O)N2CC[C@@H](c3noc(-c4ccc5c(c4)C[C@H]4CCCCN5C4)n3)C2)c1

BIRTHDAY: 2018-11-19T08:13:05.628807
ATC: N03A
- NERVOUS SYSTEM
- ANTIEPILEPTICS
- ANTIEPILEPTICS
Synthesis plan pending
FORMULA:C23H24N8O4

SMILES: Cc1ccc(C(=O)N2CC[C@@H](c3noc(C4=CNN[C@]5(C4)OCCC5=O)n3)C2)cc1-n1nccn1

BIRTHDAY: 2018-11-19T08:13:05.640626
ATC: C08C
- CARDIOVASCULAR SYSTEM
- CALCIUM CHANNEL BLOCKERS
- SELECTIVE CALCIUM CHANNEL BLOCKERS WITH MAINLY VASCULAR EFFECTS
Synthesis plan pending
FORMULA:C22H25N7O2

SMILES: COc1ccc(C(=O)N2C[C@@H]3CN(c4nc(C)cc(C)n4)C[C@H]3C2)c(-n2nccn2)c1

BIRTHDAY: 2018-11-19T08:13:05.651120
ATC: L02A
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ENDOCRINE THERAPY
- HORMONES AND RELATED AGENTS
Synthesis plan pending
FORMULA:C26H32N4O3S

SMILES: Cc1ccc(C2=COCCSCCO2)c(C(=O)N2C[C@@H]3CN(c4nc(C)cc(C)n4)C[C@@H]3C2)c1

BIRTHDAY: 2018-11-19T08:13:05.661702
ATC: M04A
- MUSCULO-SKELETAL SYSTEM
- ANTIGOUT PREPARATIONS
- ANTIGOUT PREPARATIONS
Synthesis plan pending
FORMULA:C23H21ClN6O2

SMILES: Cc1ccc(-c2nc([C@H]3CCN(C(=O)c4ccc(-n5nccn5)c(C)c4)C3)no2)cc1Cl

BIRTHDAY: 2018-11-19T08:13:05.683433
ATC: V08A
- VARIOUS
- CONTRAST MEDIA
- X-RAY CONTRAST MEDIA, IODINATED
Synthesis plan pending
FORMULA:C23H26N6O2

SMILES: COc1cccc(-c2cc[nH]n2)c1C(=O)N1C[C@@H]2CN(c3nc(C)cc(C)n3)C[C@H]2C1

BIRTHDAY: 2018-11-19T08:13:05.694187
ATC: D08A
- DERMATOLOGICALS
- ANTISEPTICS AND DISINFECTANTS
- ANTISEPTICS AND DISINFECTANTS
Synthesis plan pending
FORMULA:C23H21ClN6O2

SMILES: Cc1ccc(-n2nccn2)c(C(=O)N2CC[C@H](c3noc(-c4ccc(C)c(Cl)c4)n3)C2)c1

BIRTHDAY: 2018-11-19T08:13:05.704725
ATC: A03A
- ALIMENTARY TRACT AND METABOLISM
- DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS
- DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS
Synthesis plan pending
FORMULA:C23H27N7O

SMILES: Cc1ncnc(C)c1N1CCC[C@@]12CCCN2C(=O)c1cccc(-n2nccn2)c1C

BIRTHDAY: 2018-11-19T08:13:05.726969
ATC: M01A
- MUSCULO-SKELETAL SYSTEM
- ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS
- ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS
Synthesis plan pending
FORMULA:C23H27N5O3

SMILES: COc1cccc(OC)c1N[C@@]1([C@@H]2CCN(C(=O)c3ccccc3C)C2)C=NC=NN1

BIRTHDAY: 2018-11-19T08:13:05.737782
ATC: A03A
- ALIMENTARY TRACT AND METABOLISM
- DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS
- DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS
Synthesis plan pending
FORMULA:C25H29N7OS

SMILES: Cc1cc(C(=O)N2CCC[C@]23CCCN3c2nc(C)c3c(n2)SCCC3)ccc1-n1nccn1

BIRTHDAY: 2018-11-19T08:13:05.761320
ATC: C03X
- CARDIOVASCULAR SYSTEM
- DIURETICS
- OTHER DIURETICS
Synthesis plan pending
FORMULA:C23H26N6O2

SMILES: COc1ccc(-c2ccn[nH]2)cc1C(=O)N1C[C@H]2CCN(c3ncc(C)c(C)n3)[C@H]2C1

BIRTHDAY: 2018-11-19T08:13:05.804650
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis plan pending
FORMULA:C24H22FN7O2

SMILES: O=C(c1ccc(F)c(-n2nccn2)c1)N1CCC[C@]12CCCN2c1cncnc1-c1ccoc1

BIRTHDAY: 2018-11-19T08:13:05.827992
ATC: J05A
- ANTIINFECTIVES FOR SYSTEMIC USE
- ANTIVIRALS FOR SYSTEMIC USE
- DIRECT ACTING ANTIVIRALS
Synthesis plan pending
FORMULA:C23H26N6O2

SMILES: COc1ccc(C(=O)N2C[C@@H]3CN(c4nc(C)cc(C)n4)C[C@H]3C2)c(-c2ccn[nH]2)c1

BIRTHDAY: 2018-11-19T08:13:05.838184
ATC: A10B
- ALIMENTARY TRACT AND METABOLISM
- DRUGS USED IN DIABETES
- BLOOD GLUCOSE LOWERING DRUGS, EXCL. INSULINS
Synthesis plan pending
FORMULA:C24H28N6O2

SMILES: COc1cc(C(=O)N2CCC[C@]23CCCN3c2c(C)ncnc2C)ccc1-c1ccn[nH]1

BIRTHDAY: 2018-11-19T08:13:05.849205
ATC: N05A
- NERVOUS SYSTEM
- PSYCHOLEPTICS
- ANTIPSYCHOTICS
Synthesis plan pending
FORMULA:C24H28N6O2

SMILES: COc1cc(C(=O)N2CCC[C@@]23CCCN3c2c(C)ncnc2C)cc(-c2cn[nH]c2)c1

BIRTHDAY: 2018-11-19T08:13:05.860330
ATC: M01A
- MUSCULO-SKELETAL SYSTEM
- ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS
- ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS
Synthesis plan pending
FORMULA:C23H21FN6O2

SMILES: Cc1ccc(-c2nc([C@@H]3CCN(C(=O)c4cccc(-n5nccn5)c4C)C3)no2)cc1F

BIRTHDAY: 2018-11-19T08:13:05.870769
ATC: J05A
- ANTIINFECTIVES FOR SYSTEMIC USE
- ANTIVIRALS FOR SYSTEMIC USE
- DIRECT ACTING ANTIVIRALS
Synthesis plan pending
FORMULA:C26H24FN7O

SMILES: O=C(c1cccc(-n2nccn2)c1F)N1CCC[C@]12CCCN2c1cncnc1-c1ccccc1

BIRTHDAY: 2018-11-19T08:13:05.883376
ATC: M01A
- MUSCULO-SKELETAL SYSTEM
- ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS
- ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS
Synthesis plan pending
FORMULA:C26H24FN7O

SMILES: O=C(c1ccc(-n2nccn2)c(F)c1)N1CCC[C@]12CCCN2c1cnc(-c2ccccc2)nc1

BIRTHDAY: 2018-11-19T08:13:05.896824
ATC: N05A
- NERVOUS SYSTEM
- PSYCHOLEPTICS
- ANTIPSYCHOTICS
Synthesis plan pending
FORMULA:C22H25N7O2

SMILES: COc1ccc(-n2nccn2)c(C(=O)N2C[C@@H]3CN(c4nc(C)cc(C)n4)C[C@H]3C2)c1

BIRTHDAY: 2018-11-19T08:13:05.952658
ATC: C01B
- CARDIOVASCULAR SYSTEM
- CARDIAC THERAPY
- ANTIARRHYTHMICS, CLASS I AND III
Synthesis plan pending
FORMULA:C17H26O5

SMILES: Cc1cccc([C@H]2COCCOCCOCCOCCO2)c1

BIRTHDAY: 2018-11-19T08:13:05.960404
ATC: G03X
- GENITO URINARY SYSTEM AND SEX HORMONES
- SEX HORMONES AND MODULATORS OF THE GENITAL SYSTEM
- OTHER SEX HORMONES AND MODULATORS OF THE GENITAL SYSTEM
Synthesis plan pending
FORMULA:C19H15N5O

SMILES: Cc1ccc(-c2nc(Nc3cc(-c4ccccc4)ncn3)[n-][o+]2)cc1

BIRTHDAY: 2018-11-30T17:24:04.324231
ATC: B01A
- BLOOD AND BLOOD FORMING ORGANS
- ANTITHROMBOTIC AGENTS
- ANTITHROMBOTIC AGENTS
Synthesis Plan
FORMULA:C23H21ClN6O2

SMILES: Cc1cccc(-c2nc([C@H]3CCN(C(=O)c4cccc(-n5nccn5)c4C)C3)no2)c1Cl

BIRTHDAY: 2018-11-30T17:24:04.334627
ATC: J05A
- ANTIINFECTIVES FOR SYSTEMIC USE
- ANTIVIRALS FOR SYSTEMIC USE
- DIRECT ACTING ANTIVIRALS
Synthesis Plan
FORMULA:C30H37N7O2

SMILES: COc1cccc(C(=O)N2CCC[C@@]23CCCN3c2ncnc3c2NCCCCNc2cccc(c2)NC3)c1

BIRTHDAY: 2018-11-30T17:24:04.390035
ATC: N06A
- NERVOUS SYSTEM
- PSYCHOANALEPTICS
- ANTIDEPRESSANTS
Synthesis Plan
FORMULA:C23H34N4O4

SMILES: COC[C@@H](O)[C@H](C)OC(C)(C)CNC1=C(c2ccccc2)C(C)=NC2=NN(C)C[C@@H]2O1

BIRTHDAY: 2018-11-30T17:24:04.422307
ATC: V08C
- VARIOUS
- CONTRAST MEDIA
- MAGNETIC RESONANCE IMAGING CONTRAST MEDIA
Synthesis Plan
FORMULA:C23H21N5O2

SMILES: N#Cc1cccc(C(=O)N2CCC[C@]23CCCN3c2cncnc2-c2ccoc2)c1

BIRTHDAY: 2018-11-30T17:24:04.433047
ATC: M01A
- MUSCULO-SKELETAL SYSTEM
- ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS
- ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS
Synthesis Plan
FORMULA:C33H34FNO3

SMILES: Fc1ccc2c3ccc(c2c1)OCCCCOc1ccc(-c2ccc(OCC4CC4)cc2)c(c1)CCNC3

BIRTHDAY: 2018-11-30T17:24:04.453484
ATC: A10B
- ALIMENTARY TRACT AND METABOLISM
- DRUGS USED IN DIABETES
- BLOOD GLUCOSE LOWERING DRUGS, EXCL. INSULINS
Synthesis Plan
FORMULA:C23H27N7O

SMILES: Cc1ncc(N2CCC[C@]23CCCN3C(=O)c2ccc(-n3nccn3)c(C)c2)c(C)n1

BIRTHDAY: 2018-11-30T17:24:04.487957
ATC: C09D
- CARDIOVASCULAR SYSTEM
- AGENTS ACTING ON THE RENIN-ANGIOTENSIN SYSTEM
- ANGIOTENSIN II ANTAGONISTS, COMBINATIONS
Synthesis Plan
FORMULA:C25H30N6O2

SMILES: COc1cc(C(=O)N2CCC[C@]23CCCN3c2c(C)nc(C)nc2C)cc(-c2cn[nH]c2)c1

BIRTHDAY: 2018-12-02T16:07:12.327396
ATC: M01A
- MUSCULO-SKELETAL SYSTEM
- ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS
- ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS
Synthesis Plan
FORMULA:C24H24N6O3

SMILES: COc1ccc(-c2nc([C@@H]3CCN(C(=O)c4cccc(-n5nccn5)c4C)C3)no2)cc1C

BIRTHDAY: 2018-12-02T16:07:12.337875
ATC: N05C
- NERVOUS SYSTEM
- PSYCHOLEPTICS
- HYPNOTICS AND SEDATIVES
Synthesis Plan
FORMULA:C24H24ClN5O3

SMILES: Cc1ccc(-c2nc([C@H]3CCN(C(=O)c4cccc(N5C=NOCC5)c4C)C3)no2)cc1Cl

BIRTHDAY: 2018-12-02T16:07:12.370231
ATC: N05C
- NERVOUS SYSTEM
- PSYCHOLEPTICS
- HYPNOTICS AND SEDATIVES
Synthesis Plan
FORMULA:C13H17FN2

SMILES: Fc1ccc(C2=CCNCCCCN2)cc1

BIRTHDAY: 2018-12-02T16:07:12.408074
ATC: D11A
- DERMATOLOGICALS
- OTHER DERMATOLOGICAL PREPARATIONS
- OTHER DERMATOLOGICAL PREPARATIONS
Synthesis Plan
FORMULA:C21H27N3O

SMILES: O=C(c1ccccc1)N1CCC[C@]12CCCN2[C@@H]1C[C@@H]2C=CN1CC2

BIRTHDAY: 2018-12-02T16:07:12.417000
ATC: S01E
- SENSORY ORGANS
- OPHTHALMOLOGICALS
- ANTIGLAUCOMA PREPARATIONS AND MIOTICS
Synthesis Plan
FORMULA:C23H21ClN6O2

SMILES: Cc1ccc(-n2nccn2)c(C(=O)N2CCC[C@@H]2c2nc(-c3cc(C)ccc3Cl)no2)c1

BIRTHDAY: 2018-12-02T16:07:12.427915
ATC: C05A
- CARDIOVASCULAR SYSTEM
- VASOPROTECTIVES
- AGENTS FOR TREATMENT OF HEMORRHOIDS AND ANAL FISSURES FOR TOPICAL USE
Synthesis Plan
FORMULA:C22H21F2N3O5

SMILES: COc1ccc(-c2nc([C@@H]3CN[C@@]4(COC=CO[C@]5(F)C=CC=C[C@]5(F)O4)C3)no2)cc1

BIRTHDAY: 2018-12-02T16:07:12.438733
ATC: S01E
- SENSORY ORGANS
- OPHTHALMOLOGICALS
- ANTIGLAUCOMA PREPARATIONS AND MIOTICS
Synthesis Plan
FORMULA:C24H29N7O2

SMILES: COc1c(C(=O)N2CCC[C@]23CCCN3c2c(C)nc(C)nc2C)cccc1-n1nccn1

BIRTHDAY: 2018-12-02T16:07:12.450609
ATC: A07A
- ALIMENTARY TRACT AND METABOLISM
- ANTIDIARRHEALS, INTESTINAL ANTIINFLAMMATORY/ANTIINFECTIVE AGENTS
- INTESTINAL ANTIINFECTIVES
Synthesis Plan
FORMULA:C21H23NO2S

SMILES: COc1ccc(C2=CC(c3ccc(C)cc3)=N[C@@H](C)[C@@H](OC)S2)cc1

BIRTHDAY: 2018-12-03T10:43:34.386340
ATC: A02B
- ALIMENTARY TRACT AND METABOLISM
- DRUGS FOR ACID RELATED DISORDERS
- DRUGS FOR PEPTIC ULCER AND GASTRO-OESOPHAGEAL REFLUX DISEASE (GORD)
Synthesis Plan
FORMULA:C24H29N7O2

SMILES: COc1c(C(=O)N2CC[C@]3(CCCN3c3c(C)nc(C)nc3C)C2)cccc1-n1nccn1

BIRTHDAY: 2018-12-03T10:43:34.408175
ATC: P02C
- ANTIPARASITIC PRODUCTS, INSECTICIDES AND REPELLENTS
- ANTHELMINTICS
- ANTINEMATODAL AGENTS
Synthesis Plan
FORMULA:C22H25F3N4O2

SMILES: COc1ccc(C(F)(F)F)cc1C(=O)N1C[C@@H]2CN(c3nc(C)c(C)c(C)n3)C[C@@H]2C1

BIRTHDAY: 2018-12-03T10:43:34.441333
ATC: V08C
- VARIOUS
- CONTRAST MEDIA
- MAGNETIC RESONANCE IMAGING CONTRAST MEDIA
Synthesis Plan
FORMULA:C24H27FN4OS

SMILES: Cc1ccccc1[C@@]12C=CCN(CCC1)[C@H]2N1SC(=O)CC[C@@]1(N)c1ccnc(F)c1

BIRTHDAY: 2018-12-03T10:43:34.514921
ATC: C10A
- CARDIOVASCULAR SYSTEM
- LIPID MODIFYING AGENTS
- LIPID MODIFYING AGENTS, PLAIN
Synthesis Plan
FORMULA:C23H22N2O2S

SMILES: Cc1ccc(C(=O)N2CC[C@@]34C=CC(c5cccc(C)n5)=C[C@]23SCO4)cc1

BIRTHDAY: 2018-12-03T19:11:59.093701
ATC: V08A
- VARIOUS
- CONTRAST MEDIA
- X-RAY CONTRAST MEDIA, IODINATED
Synthesis Plan
FORMULA:C23H26N6O2

SMILES: COc1cc(C(=O)N2CC[C@H]3CCN(c4cnc(C)nc4C)[C@@H]32)cc(-c2cn[nH]c2)c1

BIRTHDAY: 2018-12-03T19:11:59.127035
ATC: D11A
- DERMATOLOGICALS
- OTHER DERMATOLOGICAL PREPARATIONS
- OTHER DERMATOLOGICAL PREPARATIONS
Synthesis Plan
FORMULA:C24H28N6O2

SMILES: COc1ccc(C(=O)N2C[C@@H]3CN(c4nc(C)c(C)c(C)n4)C[C@@H]3C2)c(-c2cc[nH]n2)c1

BIRTHDAY: 2018-12-03T19:11:59.184361
ATC: C10A
- CARDIOVASCULAR SYSTEM
- LIPID MODIFYING AGENTS
- LIPID MODIFYING AGENTS, PLAIN
Synthesis Plan
FORMULA:C28H25FN6O

SMILES: O=C(c1ccc(F)c(-c2cncnc2)c1)N1CCC[C@@]12CCCN2c1cncnc1-c1ccccc1

BIRTHDAY: 2018-12-03T19:11:59.196923
ATC: M01A
- MUSCULO-SKELETAL SYSTEM
- ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS
- ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS
Synthesis Plan
FORMULA:C22H21N5O2

SMILES: Cc1cccc(C(=O)N2CCC[C@H]2c2noc(-c3cccccncnc3)n2)c1

BIRTHDAY: 2018-12-03T19:11:59.259884
ATC: R05D
- RESPIRATORY SYSTEM
- COUGH AND COLD PREPARATIONS
- COUGH SUPPRESSANTS, EXCL. COMBINATIONS WITH EXPECTORANTS
Synthesis Plan
FORMULA:C42H44N6O5

SMILES: COc1ccc(-c2nc([C@H]3CCN(C(=O)c4cc(C)cc5c4N(C(C)C)Cc4cccc(c4)Oc4cccc(c4)C(=O)N4CCN5CC4)C3)no2)cc1

BIRTHDAY: 2018-12-01T22:31:05.216098
ATC: M01A
- MUSCULO-SKELETAL SYSTEM
- ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS
- ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS
Synthesis Plan
FORMULA:C22H25N7O

SMILES: Cc1ccc(C(=O)N2C[C@@H]3CN(c4nc(C)cc(C)n4)C[C@@H]3C2)c(-n2nccn2)c1

BIRTHDAY: 2018-12-01T22:31:05.236511
ATC: L01B
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- ANTIMETABOLITES
Synthesis Plan
FORMULA:C17H13F4NO

SMILES: Fc1ccc(C2=NOC[C@@H](c3ccc(C(F)(F)F)cc3)C2)cc1

BIRTHDAY: 2018-12-01T22:31:05.310692
ATC: A10B
- ALIMENTARY TRACT AND METABOLISM
- DRUGS USED IN DIABETES
- BLOOD GLUCOSE LOWERING DRUGS, EXCL. INSULINS
Synthesis Plan
FORMULA:C25H22FN7O

SMILES: O=C(c1c(F)cccc1-n1nccn1)N1C[C@@H]2CCN(c3nccc(-c4ccccc4)n3)[C@@H]2C1

BIRTHDAY: 2018-12-01T22:31:05.343036
ATC: R03D
- RESPIRATORY SYSTEM
- DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES
- OTHER SYSTEMIC DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES
Synthesis Plan
FORMULA:C25H30N6O2

SMILES: COc1cc(C(=O)N2CC[C@@]3(CCCN3c3c(C)nc(C)nc3C)C2)cc(-c2cn[nH]c2)c1

BIRTHDAY: 2018-12-01T22:31:05.364510
ATC: J01F
- ANTIINFECTIVES FOR SYSTEMIC USE
- ANTIBACTERIALS FOR SYSTEMIC USE
- MACROLIDES, LINCOSAMIDES AND STREPTOGRAMINS
Synthesis Plan