matter.farm

Computer-generated molecule database for public drug discovery. About this project.

These compounds may interact with:

RAF proto-oncogene serine/threonine-protein kinase

Potentially involved in: cardiomyopathy; leopard syndrome; cancer; noonan syndrome; heart disease; kidney cancer; carcinoma; yellow fever; hepatitis; dengue disease; hepatitis c; tick-borne encephalitis; murray valley encephalitis; encephalitis; st. louis encephalitis; liver cirrhosis; microcephaly; lung adenoma; cardiac arrhythmia; blepharoptosis

Disease data sourced from Pharos.

Antagonist

FORMULA:C22H18ClN5O4

SMILES: CNC(=O)c1cnccc1Oc1cccc2oc(Nc3cccc(C(=O)NC)c3Cl)nc12

BIRTHDAY: 2018-12-01T14:10:26.793452
ATC: N07X
- NERVOUS SYSTEM
- OTHER NERVOUS SYSTEM DRUGS
- OTHER NERVOUS SYSTEM DRUGS
Synthesis Plan
FORMULA:C27H28N2O4

SMILES: C[C@H](NC(=O)c1cccc(-c2ccccc2C(=O)Nc2cccc(C(C)(C)C)c2)c1)C(=O)O

BIRTHDAY: 2018-12-01T14:10:26.803156
ATC: V09C
- VARIOUS
- DIAGNOSTIC RADIOPHARMACEUTICALS
- RENAL SYSTEM
Synthesis Plan
FORMULA:C27H27FN2O3

SMILES: O=C(NCC1(O)CCCCC1)c1ccc(NC(=O)c2cccc(-c3cccc(F)c3)c2)cc1

BIRTHDAY: 2018-12-01T14:10:26.812512
ATC: L02B
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ENDOCRINE THERAPY
- HORMONE ANTAGONISTS AND RELATED AGENTS
Synthesis Plan
FORMULA:C27H28N2O4

SMILES: C[C@@H](NC(=O)c1cccc(NC(=O)c2ccccc2-c2ccccc2C(C)(C)C)c1)C(=O)O

BIRTHDAY: 2018-12-01T14:10:26.821952
ATC: C10A
- CARDIOVASCULAR SYSTEM
- LIPID MODIFYING AGENTS
- LIPID MODIFYING AGENTS, PLAIN
Synthesis Plan
FORMULA:C23H28O6

SMILES: CC(C)(C)c1cccc2c1OCCOC[C@@H](c1ccc(C(=O)O)cc1)OCCO2

BIRTHDAY: 2018-12-01T14:10:26.830718
ATC: G03X
- GENITO URINARY SYSTEM AND SEX HORMONES
- SEX HORMONES AND MODULATORS OF THE GENITAL SYSTEM
- OTHER SEX HORMONES AND MODULATORS OF THE GENITAL SYSTEM
Synthesis Plan
FORMULA:C41H39N5O4S

SMILES: CNC(=O)c1ccc(-c2ccc(C(=O)Nc3cccc([C@H]4N=CS[C@@H]5C=C6C=C[C@]54CCNCc4cccc(c4)NC(=O)OCC6)c3)cc2)cc1

BIRTHDAY: 2018-12-01T14:10:26.844961
ATC: M01A
- MUSCULO-SKELETAL SYSTEM
- ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS
- ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS
Synthesis Plan
FORMULA:C22H18N4O3

SMILES: CNC(=O)c1ccc(-c2ccc3ncnc(Nc4ccc(O)c(O)c4)c3c2)cc1

BIRTHDAY: 2018-12-01T14:10:26.854311
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C26H32N4O3

SMILES: COc1ccc(CC(=O)Nc2cc(C(C)(C)C)nn2CC(=O)Nc2c(C)cccc2C)cc1

BIRTHDAY: 2018-12-01T14:10:26.864072
ATC: G02A
- GENITO URINARY SYSTEM AND SEX HORMONES
- OTHER GYNECOLOGICALS
- UTEROTONICS
Synthesis Plan
FORMULA:C29H35N3O2

SMILES: CN(C)CCCNC(=O)c1cccc(NC(=O)c2ccc(-c3ccc(C(C)(C)C)cc3)cc2)c1

BIRTHDAY: 2018-12-01T14:10:26.873019
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C30H34ClNO2

SMILES: CC(C)(C)c1ccc([C@@H]2[C@@H](c3ccc(Cl)cc3)[C@@H]3C[C@H]4[C@H]5O[C@H]([C@H]6C(=O)CCC[C@]56C3)N42)cc1

BIRTHDAY: 2018-12-01T14:10:26.883158
ATC: C01B
- CARDIOVASCULAR SYSTEM
- CARDIAC THERAPY
- ANTIARRHYTHMICS, CLASS I AND III
Synthesis Plan
FORMULA:C27H27N5O2

SMILES: COc1ccc(-c2cccc3nc(Nc4ccccc4N4CCN(C(C)=O)CC4)ncc23)cc1

BIRTHDAY: 2018-12-01T14:10:26.904245
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C22H18FN3O3S

SMILES: O=C(Nc1ccc(C2=CNCNS2(=O)=O)cc1)c1ccccc1-c1cccc(F)c1

BIRTHDAY: 2018-12-01T14:10:26.913974
ATC: C03X
- CARDIOVASCULAR SYSTEM
- DIURETICS
- OTHER DIURETICS
Synthesis Plan
FORMULA:C29H35N3O2

SMILES: CN(C)C(C)(C)NC(=O)c1ccccc1NC(=O)c1cccc(-c2ccccc2C(C)(C)C)c1

BIRTHDAY: 2018-12-01T14:10:26.923175
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C30H31F3N6O2

SMILES: Cn1ncc2c1NC(=O)CN(C(=O)c1ccc(-c3ccc(C(C)(C)C)cc3)cc1)CC[C@H]2c1c[nH]nc1C(F)(F)F

BIRTHDAY: 2018-12-01T14:10:26.936123
ATC: J05A
- ANTIINFECTIVES FOR SYSTEMIC USE
- ANTIVIRALS FOR SYSTEMIC USE
- DIRECT ACTING ANTIVIRALS
Synthesis Plan
FORMULA:C29H22F3N3O3

SMILES: CNC(=O)c1ccccc1-c1ccc(C(=O)Nc2ccccc2C(=O)Nc2cccc(C(F)(F)F)c2)cc1

BIRTHDAY: 2018-12-01T14:10:26.957421
ATC: V09C
- VARIOUS
- DIAGNOSTIC RADIOPHARMACEUTICALS
- RENAL SYSTEM
Synthesis Plan
FORMULA:C29H33N5O

SMILES: CN(C)CCNC(=O)c1ccc(-c2ccc3ncnc(Nc4ccc(C(C)(C)C)cc4)c3c2)cc1

BIRTHDAY: 2018-12-01T14:10:26.967147
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C27H27N5O2

SMILES: COc1ccccc1-c1cccc2c(Nc3ccccc3N3CCN(C(C)=O)CC3)ncnc12

BIRTHDAY: 2018-12-01T14:10:26.977653
ATC: N03A
- NERVOUS SYSTEM
- ANTIEPILEPTICS
- ANTIEPILEPTICS
Synthesis Plan
FORMULA:C29H35N3O2

SMILES: CN(C)C(C)(C)NC(=O)c1ccccc1NC(=O)c1ccccc1-c1ccccc1C(C)(C)C

BIRTHDAY: 2018-12-25T02:02:29.300642
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C22H18ClN5O4

SMILES: CNC(=O)c1cc(Oc2ccc3oc(Nc4ccc(Cl)cc4C(=O)NC)nc3c2)ccn1

BIRTHDAY: 2018-12-25T02:02:29.311371
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C28H26N6O5

SMILES: COc1ccc2c(c1)OCC=CCOc1nc(cnc1-c1ccc(C(=O)NC3(C#N)CC3)cc1)N(C)C(=O)N2

BIRTHDAY: 2018-12-25T02:02:29.323484
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C25H23F3N2O2

SMILES: CC(C)(C)c1cccc(C(=O)Nc2cccc(C(=O)Nc3cccc(C(F)(F)F)c3)c2)c1

BIRTHDAY: 2018-12-25T02:02:29.332989
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C23H18F3N3O3

SMILES: CNC(=O)c1ccccc1C(=O)Nc1cccc(C(=O)Nc2cccc(C(F)(F)F)c2)c1

BIRTHDAY: 2018-12-25T02:02:29.343155
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C22H18ClN5O4

SMILES: CNC(=O)c1cc(Oc2ccc3nc(Nc4ccc(Cl)c(C(=O)NC)c4)oc3c2)ccn1

BIRTHDAY: 2018-12-25T02:02:29.353857
ATC: R05D
- RESPIRATORY SYSTEM
- COUGH AND COLD PREPARATIONS
- COUGH SUPPRESSANTS, EXCL. COMBINATIONS WITH EXPECTORANTS
Synthesis Plan
FORMULA:C20H13FNO2Ru

SMILES: O=[C-]c1ccc(NC(=O)c2ccc(-c3ccc(F)cc3)cc2)cc1.[Ru+]

BIRTHDAY: 2018-12-25T02:02:29.362013
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C21H20F2N4O4

SMILES: COc1ccc(CCNC(=O)c2n[nH]cc2C(=O)Nc2c(F)cccc2F)cc1OC

BIRTHDAY: 2018-12-25T02:02:29.372389
ATC: R07A
- RESPIRATORY SYSTEM
- OTHER RESPIRATORY SYSTEM PRODUCTS
- OTHER RESPIRATORY SYSTEM PRODUCTS
Synthesis Plan
FORMULA:C24H27NO4

SMILES: CNC(=O)c1ccccc1[C@@]1(C)C=CC=CCCC(=O)[C@@H]2CCC=C(CO2)C1=O

BIRTHDAY: 2018-12-25T02:02:29.393135
ATC: D11A
- DERMATOLOGICALS
- OTHER DERMATOLOGICAL PREPARATIONS
- OTHER DERMATOLOGICAL PREPARATIONS
Synthesis Plan
FORMULA:C24H25N5O2

SMILES: CNC(=O)c1ccncc1Oc1cccc2nc(Nc3ccccc3C(C)(C)C)[nH]c12

BIRTHDAY: 2018-12-25T02:02:29.403109
ATC: P02C
- ANTIPARASITIC PRODUCTS, INSECTICIDES AND REPELLENTS
- ANTHELMINTICS
- ANTINEMATODAL AGENTS
Synthesis Plan
FORMULA:C27H27N5O2

SMILES: COc1ccccc1-c1ccc2c(Nc3ccc(N4CCN(C(C)=O)CC4)cc3)ncnc2c1

BIRTHDAY: 2018-12-25T02:02:29.413065
ATC: N05A
- NERVOUS SYSTEM
- PSYCHOLEPTICS
- ANTIPSYCHOTICS
Synthesis Plan
FORMULA:C23H19FN2O2

SMILES: O[C@@]12C=CC=C[C@H]1[C@]1(CO2)C[C@H]1c1nc2cccc(-c3cccc(F)c3)c2[nH]1

BIRTHDAY: 2018-12-25T02:02:29.432922
ATC: A03F
- ALIMENTARY TRACT AND METABOLISM
- DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS
- PROPULSIVES
Synthesis Plan
FORMULA:C33H36N2O3S

SMILES: CCCCCCOc1ccc(Cc2nc3cc(n2)-c2cccc(c2)OCCCCOc2cccc(c2)S3)cc1

BIRTHDAY: 2018-12-25T02:02:29.443675
ATC: D06A
- DERMATOLOGICALS
- ANTIBIOTICS AND CHEMOTHERAPEUTICS FOR DERMATOLOGICAL USE
- ANTIBIOTICS FOR TOPICAL USE
Synthesis Plan
FORMULA:C23H18F3N3O3

SMILES: CNC(=O)c1ccc(C(=O)Nc2ccccc2C(=O)Nc2cccc(C(F)(F)F)c2)cc1

BIRTHDAY: 2018-12-25T02:02:29.454478
ATC: V09C
- VARIOUS
- DIAGNOSTIC RADIOPHARMACEUTICALS
- RENAL SYSTEM
Synthesis Plan
FORMULA:C24H17N3O

SMILES: N#Cc1cccc(-c2ccc(Nc3ccc(Oc4ccccc4)cc3)nc2)c1

BIRTHDAY: 2018-12-25T02:02:29.475411
ATC: M01A
- MUSCULO-SKELETAL SYSTEM
- ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS
- ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS
Synthesis Plan
FORMULA:C27H31NO

SMILES: CC(C)(C)c1ccc(NC(=O)c2ccc(-c3ccc(C(C)(C)C)cc3)cc2)cc1

BIRTHDAY: 2018-12-25T02:02:29.482843
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C29H22F3N3O3

SMILES: CNC(=O)c1ccc(NC(=O)c2ccc(-c3ccc(C(=O)Nc4ccccc4C(F)(F)F)cc3)cc2)cc1

BIRTHDAY: 2018-12-03T02:38:33.327846
ATC: G03X
- GENITO URINARY SYSTEM AND SEX HORMONES
- SEX HORMONES AND MODULATORS OF THE GENITAL SYSTEM
- OTHER SEX HORMONES AND MODULATORS OF THE GENITAL SYSTEM
Synthesis Plan
FORMULA:C25H26N6O

SMILES: COc1cccc(-c2cccc3c(Nc4ccccc4N4CCNC[C@H]4N)ncnc23)c1

BIRTHDAY: 2018-12-03T02:38:33.338169
ATC: N06A
- NERVOUS SYSTEM
- PSYCHOANALEPTICS
- ANTIDEPRESSANTS
Synthesis Plan
FORMULA:C26H31FN4O3

SMILES: COc1cccc(CC(=O)Nc2cc(C(C)(C)C)n(CC(=O)N[C@@H](C)c3ccccc3F)n2)c1

BIRTHDAY: 2018-12-03T02:38:33.348619
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C29H35N3O2

SMILES: CN(C)C(C)(C)NC(=O)c1ccccc1NC(=O)c1cccc(-c2cccc(C(C)(C)C)c2)c1

BIRTHDAY: 2018-12-03T02:38:33.369252
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C22H18ClN5O4

SMILES: CNC(=O)c1ccncc1Oc1cccc2oc(Nc3cccc(C(=O)NC)c3Cl)nc12

BIRTHDAY: 2018-12-03T02:38:33.380018
ATC: P01B
- ANTIPARASITIC PRODUCTS, INSECTICIDES AND REPELLENTS
- ANTIPROTOZOALS
- ANTIMALARIALS
Synthesis Plan
FORMULA:C24H17N3O

SMILES: N#Cc1ccccc1-c1ccc(Nc2ccccc2Oc2ccccc2)cn1

BIRTHDAY: 2018-12-03T02:38:33.388143
ATC: N05B
- NERVOUS SYSTEM
- PSYCHOLEPTICS
- ANXIOLYTICS
Synthesis Plan
FORMULA:C25H28N4O4

SMILES: CNC(=O)c1cncc(C(=O)NCCc2ccc(OC)cc2)c1NCc1ccccc1OC

BIRTHDAY: 2018-12-03T02:38:33.398046
ATC: R07A
- RESPIRATORY SYSTEM
- OTHER RESPIRATORY SYSTEM PRODUCTS
- OTHER RESPIRATORY SYSTEM PRODUCTS
Synthesis Plan
FORMULA:C22H17N3O2

SMILES: O=C(Nc1ccccc1O)c1cccc(-c2cccc(-c3c[nH]cn3)c2)c1

BIRTHDAY: 2018-12-03T02:38:33.406758
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C27H27N5O2

SMILES: COc1ccc(-c2cccc3cnc(Nc4ccccc4N4CCN(C(C)=O)CC4)nc23)cc1

BIRTHDAY: 2018-12-03T02:38:33.417134
ATC: M01A
- MUSCULO-SKELETAL SYSTEM
- ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS
- ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS
Synthesis Plan
FORMULA:C27H27N5O2

SMILES: COc1cccc(-c2cccc3cnc(Nc4ccccc4N4CCN(C(C)=O)CC4)nc23)c1

BIRTHDAY: 2018-12-03T02:38:33.427455
ATC: M01A
- MUSCULO-SKELETAL SYSTEM
- ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS
- ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS
Synthesis Plan
FORMULA:C22H18ClN5O4

SMILES: CNC(=O)c1ccc(Cl)c(Nc2nc3cc(Oc4ccnc(C(=O)NC)c4)ccc3o2)c1

BIRTHDAY: 2018-12-03T02:38:33.448561
ATC: C05B
- CARDIOVASCULAR SYSTEM
- VASOPROTECTIVES
- ANTIVARICOSE THERAPY
Synthesis Plan
FORMULA:C25H23F3N2O2

SMILES: CC(C)(C)c1cccc(C(=O)Nc2ccc(C(=O)Nc3ccccc3C(F)(F)F)cc2)c1

BIRTHDAY: 2018-12-03T02:38:33.458095
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C25H26N6O

SMILES: COc1cccc(-c2cccc3cnc(Nc4ccccc4N4CCNC[C@H]4N)nc23)c1

BIRTHDAY: 2018-12-03T02:38:33.468158
ATC: N05A
- NERVOUS SYSTEM
- PSYCHOLEPTICS
- ANTIPSYCHOTICS
Synthesis Plan
FORMULA:C22H18ClN5O4

SMILES: CNC(=O)c1cccnc1Oc1cccc2oc(Nc3cccc(C(=O)NC)c3Cl)nc12

BIRTHDAY: 2018-11-30T03:40:29.623624
ATC: P01B
- ANTIPARASITIC PRODUCTS, INSECTICIDES AND REPELLENTS
- ANTIPROTOZOALS
- ANTIMALARIALS
Synthesis Plan
FORMULA:C28H28N4O

SMILES: CC(C)(C)c1ccc(Nc2ncnc3ccc(-c4cccc(C(=O)NC5CC5)c4)cc23)cc1

BIRTHDAY: 2018-11-30T03:40:29.633167
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C27H28N2O4

SMILES: C[C@@H](NC(=O)c1cccc(-c2ccccc2C(=O)Nc2ccccc2C(C)(C)C)c1)C(=O)O

BIRTHDAY: 2018-11-30T03:40:29.654223
ATC: G01A
- GENITO URINARY SYSTEM AND SEX HORMONES
- GYNECOLOGICAL ANTIINFECTIVES AND ANTISEPTICS
- ANTIINFECTIVES AND ANTISEPTICS, EXCL. COMBINATIONS WITH CORTICOSTEROIDS
Synthesis Plan
FORMULA:C22H18ClN5O4

SMILES: CNC(=O)c1ccc(Cl)c(Nc2nc3ccc(Oc4ccnc(C(=O)NC)c4)cc3o2)c1

BIRTHDAY: 2018-11-30T03:40:29.664608
ATC: S01X
- SENSORY ORGANS
- OPHTHALMOLOGICALS
- OTHER OPHTHALMOLOGICALS
Synthesis Plan
FORMULA:C29H22F3N3O3

SMILES: CNC(=O)c1ccccc1NC(=O)c1ccccc1-c1cccc(C(=O)Nc2ccc(C(F)(F)F)cc2)c1

BIRTHDAY: 2018-11-30T03:40:29.675952
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C26H24N4O2

SMILES: Cc1ccccc1-c1ccc(C(=O)Nc2cccc(C(=O)NCCc3ccn[nH]3)c2)cc1

BIRTHDAY: 2018-11-30T03:40:29.696081
ATC: N02B
- NERVOUS SYSTEM
- ANALGESICS
- OTHER ANALGESICS AND ANTIPYRETICS
Synthesis Plan
FORMULA:C27H28FN3O2

SMILES: CC(C)(NC(=O)c1ccccc1NC(=O)c1cccc(-c2cccc(F)c2)c1)N1CCCC1

BIRTHDAY: 2018-11-30T03:40:29.705906
ATC: M03A
- MUSCULO-SKELETAL SYSTEM
- MUSCLE RELAXANTS
- MUSCLE RELAXANTS, PERIPHERALLY ACTING AGENTS
Synthesis Plan
FORMULA:C22H18ClN5O4

SMILES: CNC(=O)c1ccc(Oc2cccc3oc(Nc4cccc(C(=O)NC)c4Cl)nc23)nc1

BIRTHDAY: 2018-11-30T03:40:29.716306
ATC: N01A
- NERVOUS SYSTEM
- ANESTHETICS
- ANESTHETICS, GENERAL
Synthesis Plan
FORMULA:C24H23F3N2O2

SMILES: C[C@]12C=CC=C[C@@]1(O)NC=CNC[C@@]2(O)c1ccccc1-c1ccccc1C(F)(F)F

BIRTHDAY: 2018-11-30T03:40:29.726458
ATC: V03A
- VARIOUS
- ALL OTHER THERAPEUTIC PRODUCTS
- ALL OTHER THERAPEUTIC PRODUCTS
Synthesis Plan
FORMULA:C22H18ClN5O4

SMILES: CNC(=O)c1cc(Oc2ccc3nc(Nc4ccc(Cl)cc4C(=O)NC)oc3c2)ccn1

BIRTHDAY: 2018-11-30T03:40:29.737013
ATC: S01X
- SENSORY ORGANS
- OPHTHALMOLOGICALS
- OTHER OPHTHALMOLOGICALS
Synthesis Plan
FORMULA:C19H12F3N3

SMILES: N#Cc1cccc(-c2cccnc2Nc2ccc(C(F)(F)F)cc2)c1

BIRTHDAY: 2018-11-30T03:40:29.755687
ATC: N06A
- NERVOUS SYSTEM
- PSYCHOANALEPTICS
- ANTIDEPRESSANTS
Synthesis Plan
FORMULA:C12H10F3N3O2S2

SMILES: CC(=O)NC1=NSS[C@H]1C(=O)Nc1ccccc1C(F)(F)F

BIRTHDAY: 2018-11-30T03:40:29.765125
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C31H39NO

SMILES: CC(C)(C)c1ccc(NC(=O)c2ccc(-c3ccccc3C(C)(C)C)c(C(C)(C)C)c2)cc1

BIRTHDAY: 2018-11-30T03:40:29.773368
ATC: C09C
- CARDIOVASCULAR SYSTEM
- AGENTS ACTING ON THE RENIN-ANGIOTENSIN SYSTEM
- ANGIOTENSIN II ANTAGONISTS, PLAIN
Synthesis Plan
FORMULA:C37H36N4O4

SMILES: CNC(=O)c1cccc(-c2ccc(C(=O)Nc3cccc(C(=O)Nc4ccc([C@]56CCN7[C@@H](CCO[C@@H]7C5)C6)cc4)c3)cc2)c1

BIRTHDAY: 2018-11-30T03:40:29.785803
ATC: J01M
- ANTIINFECTIVES FOR SYSTEMIC USE
- ANTIBACTERIALS FOR SYSTEMIC USE
- QUINOLONE ANTIBACTERIALS
Synthesis Plan
FORMULA:C29H22F3N3O3

SMILES: CNC(=O)c1ccc(-c2cccc(C(=O)Nc3ccc(C(=O)Nc4ccccc4C(F)(F)F)cc3)c2)cc1

BIRTHDAY: 2018-11-30T03:40:29.797205
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C30H36N2O2

SMILES: C[C@@H](NC(=O)c1cccc(NC(=O)c2ccccc2-c2cccc(C(C)(C)C)c2)c1)C(C)(C)C

BIRTHDAY: 2018-11-19T08:11:59.911712
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C22H25FO

SMILES: CC(C)(C)c1ccc([C@H]2C=COC[C@@H](c3ccc(F)cc3)C2)cc1

BIRTHDAY: 2018-11-19T08:11:59.918947
ATC: N06A
- NERVOUS SYSTEM
- PSYCHOANALEPTICS
- ANTIDEPRESSANTS
Synthesis Plan
FORMULA:C27H28FN3O3

SMILES: CC(C)(NC(=O)c1ccccc1NC(=O)c1ccccc1-c1ccc(F)cc1)N1CCOCC1

BIRTHDAY: 2018-11-19T08:11:59.929173
ATC: R05D
- RESPIRATORY SYSTEM
- COUGH AND COLD PREPARATIONS
- COUGH SUPPRESSANTS, EXCL. COMBINATIONS WITH EXPECTORANTS
Synthesis Plan
FORMULA:C33H45NOS

SMILES: CC(C)(C)c1cccc(-c2ccccc2C(=O)Nc2csc(C(C)(C)C)c2C(C)(C)C)c1C(C)(C)C

BIRTHDAY: 2018-11-19T08:11:59.939302
ATC: C02K
- CARDIOVASCULAR SYSTEM
- ANTIHYPERTENSIVES
- OTHER ANTIHYPERTENSIVES
Synthesis Plan
FORMULA:C27H24ClN5O3

SMILES: CNC(=O)c1cc(Oc2cccc3oc(Nc4ccc(C5=CC=CN(C)CC5)c(Cl)c4)nc23)ccn1

BIRTHDAY: 2018-11-19T08:11:59.950216
ATC: L04A
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- IMMUNOSUPPRESSANTS
- IMMUNOSUPPRESSANTS
Synthesis Plan
FORMULA:C19H15N3OS3

SMILES: COc1ccccc1-c1ccnc(Nc2cccc(C3=CSSS3)c2)n1

BIRTHDAY: 2018-11-19T08:11:59.959082
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C27H27N5O2

SMILES: COc1ccccc1-c1cccc2ncnc(Nc3ccccc3N3CCN(C(C)=O)CC3)c12

BIRTHDAY: 2018-11-19T08:11:59.971699
ATC: N05A
- NERVOUS SYSTEM
- PSYCHOLEPTICS
- ANTIPSYCHOTICS
Synthesis Plan
FORMULA:C27H27N5O2

SMILES: COc1ccc(-c2cccc3ncnc(Nc4ccccc4N4CCN(C(C)=O)CC4)c23)cc1

BIRTHDAY: 2018-11-19T08:11:59.983460
ATC: D11A
- DERMATOLOGICALS
- OTHER DERMATOLOGICAL PREPARATIONS
- OTHER DERMATOLOGICAL PREPARATIONS
Synthesis Plan
FORMULA:C26H32N4O3

SMILES: COc1ccccc1CC(=O)Nc1cn(CC(=O)N[C@@H](C)c2ccccc2)nc1C(C)(C)C

BIRTHDAY: 2018-11-19T08:11:59.993486
ATC: C01E
- CARDIOVASCULAR SYSTEM
- CARDIAC THERAPY
- OTHER CARDIAC PREPARATIONS
Synthesis Plan
FORMULA:C40H43N7O3

SMILES: COc1ccccc1-c1ccc2ncnc(Nc3ccc(N4CCN(C5=CC(=O)OCCNCc6cccc(c6)CNCC5)CC4)cc3)c2c1

BIRTHDAY: 2018-11-19T08:12:00.007222
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C38H54N6O2

SMILES: C[C@H](NC(=O)c1cccc(NC(=O)c2ccccc2-c2ccccc2C(C)(C)C)c1)[C@H]1CCCNCCCNCCNCCNC1

BIRTHDAY: 2018-11-19T08:12:00.030167
ATC: C10A
- CARDIOVASCULAR SYSTEM
- LIPID MODIFYING AGENTS
- LIPID MODIFYING AGENTS, PLAIN
Synthesis Plan
FORMULA:C33H34N8O2

SMILES: CC1(Oc2ccccc2-c2ncnc3c2C[C@@H]2CCC[C@@]3(N3CC(=O)N=Cc4[nH]c(-c5ccncc5)nc43)N2)CCCC1

BIRTHDAY: 2018-11-19T08:12:00.056166
ATC: A02B
- ALIMENTARY TRACT AND METABOLISM
- DRUGS FOR ACID RELATED DISORDERS
- DRUGS FOR PEPTIC ULCER AND GASTRO-OESOPHAGEAL REFLUX DISEASE (GORD)
Synthesis Plan
FORMULA:C27H28FN3O3

SMILES: CC(C)(NC(=O)c1ccc(NC(=O)c2cccc(-c3cccc(F)c3)c2)cc1)N1CCOCC1

BIRTHDAY: 2018-11-19T08:12:00.087033
ATC: J01M
- ANTIINFECTIVES FOR SYSTEMIC USE
- ANTIBACTERIALS FOR SYSTEMIC USE
- QUINOLONE ANTIBACTERIALS
Synthesis Plan
FORMULA:C30H30N2O

SMILES: CC(C)(C)c1ccc(-c2ccc(C(=O)Nc3ccc(C4=CC=CNCC=C4)cc3)cc2)cc1

BIRTHDAY: 2018-11-19T08:12:00.104610
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C21H30N4O3

SMILES: COc1ccc(CC(=O)Nc2cn(CC(=O)NC(C)C)nc2C(C)(C)C)cc1

BIRTHDAY: 2018-11-19T08:12:00.113670
ATC: D11A
- DERMATOLOGICALS
- OTHER DERMATOLOGICAL PREPARATIONS
- OTHER DERMATOLOGICAL PREPARATIONS
Synthesis Plan
FORMULA:C19H18N4O2S

SMILES: Cc1cccc(C)c1NC(=O)Nc1ccc(C(=O)Nc2nccs2)cc1

BIRTHDAY: 2018-11-19T08:12:00.122455
ATC: B01A
- BLOOD AND BLOOD FORMING ORGANS
- ANTITHROMBOTIC AGENTS
- ANTITHROMBOTIC AGENTS
Synthesis Plan
FORMULA:C21H30N4O3

SMILES: COc1ccccc1CC(=O)Nc1cc(C(C)(C)C)n(CC(=O)NC(C)C)n1

BIRTHDAY: 2018-11-19T08:12:00.143037
ATC: M03A
- MUSCULO-SKELETAL SYSTEM
- MUSCLE RELAXANTS
- MUSCLE RELAXANTS, PERIPHERALLY ACTING AGENTS
Synthesis Plan
FORMULA:C27H28FN3O3

SMILES: O=C(NCCCN1CCOCC1)c1cccc(NC(=O)c2ccc(-c3ccccc3F)cc2)c1

BIRTHDAY: 2018-11-19T08:12:00.173196
ATC: B01A
- BLOOD AND BLOOD FORMING ORGANS
- ANTITHROMBOTIC AGENTS
- ANTITHROMBOTIC AGENTS
Synthesis Plan
FORMULA:C23H18F3N3O3

SMILES: CNC(=O)c1cccc(C(=O)Nc2ccc(C(=O)Nc3ccccc3C(F)(F)F)cc2)c1

BIRTHDAY: 2018-11-19T08:12:00.183504
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C29H35N3O2

SMILES: CN(C)C(C)(C)NC(=O)c1ccccc1NC(=O)c1ccccc1-c1cccc(C(C)(C)C)c1

BIRTHDAY: 2018-11-19T08:12:00.192894
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C22H17F3N2O3

SMILES: COc1cccc(C(=O)Nc2ccccc2C(=O)Nc2ccc(C(F)(F)F)cc2)c1

BIRTHDAY: 2018-11-19T08:12:00.203044
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C29H35N3O2

SMILES: CN(C)C(C)(C)NC(=O)c1ccc(NC(=O)c2ccccc2-c2cccc(C(C)(C)C)c2)cc1

BIRTHDAY: 2018-11-19T08:12:00.212215
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C28H30FN3O2

SMILES: CC(C)(NC(=O)c1ccccc1NC(=O)c1ccccc1-c1cccc(F)c1)N1CCCCC1

BIRTHDAY: 2018-11-19T08:12:00.222379
ATC: V09C
- VARIOUS
- DIAGNOSTIC RADIOPHARMACEUTICALS
- RENAL SYSTEM
Synthesis Plan
FORMULA:C26H31FN4O3

SMILES: COc1ccccc1CC(=O)Nc1nn(CC(=O)N[C@@H](C)c2ccccc2F)cc1C(C)(C)C

BIRTHDAY: 2018-11-19T08:12:00.262645
ATC: A10A
- ALIMENTARY TRACT AND METABOLISM
- DRUGS USED IN DIABETES
- INSULINS AND ANALOGUES
Synthesis Plan
FORMULA:C21H25NO3S

SMILES: CC(C)(C)c1ccccc1-c1cccc(C(=O)N2CCCCS2(=O)=O)c1

BIRTHDAY: 2018-11-19T08:12:00.270732
ATC: M01A
- MUSCULO-SKELETAL SYSTEM
- ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS
- ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS
Synthesis Plan
FORMULA:C24H28ClN3

SMILES: CC(C)(C)C12CCC(CC1)N2c1cnc2c(n1)C=C[C@@H](c1ccccc1Cl)C2

BIRTHDAY: 2018-11-19T08:12:00.279067
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C12H21NO3

SMILES: CC(C)[C@@H]1C[C@@]2(C)CO[C@@](NC3CC3)(O1)O2

BIRTHDAY: 2018-11-19T08:12:00.295883
ATC: C10A
- CARDIOVASCULAR SYSTEM
- LIPID MODIFYING AGENTS
- LIPID MODIFYING AGENTS, PLAIN
Synthesis Plan
FORMULA:C21H20F2N4O4

SMILES: COc1cccc([C@H](C)NC(=O)c2[nH]ncc2C(=O)Nc2c(F)cccc2F)c1OC

BIRTHDAY: 2018-11-19T08:12:00.306290
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C28H36N4O3

SMILES: COc1ccc(CC(=O)Nc2cc(C(C)(C)C)nn2CC(=O)Nc2ccc(C(C)(C)C)cc2)cc1

BIRTHDAY: 2018-11-19T08:12:00.316538
ATC: N02B
- NERVOUS SYSTEM
- ANALGESICS
- OTHER ANALGESICS AND ANTIPYRETICS
Synthesis Plan
FORMULA:C44H43N7O

SMILES: CNC(=O)c1cccc(-c2ccc3nc(Nc4ccc(C5=CC6=NC5=Cc5ccc([nH]5)CCCCCCCCCc5ccc6[nH]5)cc4)ncc3c2)c1

BIRTHDAY: 2018-11-19T08:12:00.330417
ATC: A10B
- ALIMENTARY TRACT AND METABOLISM
- DRUGS USED IN DIABETES
- BLOOD GLUCOSE LOWERING DRUGS, EXCL. INSULINS
Synthesis Plan
FORMULA:C25H27NO4

SMILES: CC(C)(C)c1ccc(-c2ccc3c(c2)OC(=O)O[C@@]24CC[C@H]5O[C@H](CN2)[C@@H]4[C@@H]35)cc1

BIRTHDAY: 2018-11-19T08:12:00.339616
ATC: J02A
- ANTIINFECTIVES FOR SYSTEMIC USE
- ANTIMYCOTICS FOR SYSTEMIC USE
- ANTIMYCOTICS FOR SYSTEMIC USE
Synthesis Plan
FORMULA:C29H35N3O2

SMILES: CN(C)CCCNC(=O)c1ccccc1-c1ccc(C(=O)Nc2ccc(C(C)(C)C)cc2)cc1

BIRTHDAY: 2018-11-19T08:12:00.359668
ATC: N02B
- NERVOUS SYSTEM
- ANALGESICS
- OTHER ANALGESICS AND ANTIPYRETICS
Synthesis Plan
FORMULA:C29H35N3O2

SMILES: CN(C)C(C)(C)NC(=O)c1ccc(-c2ccccc2C(=O)Nc2ccccc2C(C)(C)C)cc1

BIRTHDAY: 2018-11-19T08:12:00.369216
ATC: C02K
- CARDIOVASCULAR SYSTEM
- ANTIHYPERTENSIVES
- OTHER ANTIHYPERTENSIVES
Synthesis Plan
FORMULA:C29H33N5O

SMILES: C[C@@H](NC(=O)c1ccccc1-c1cccc2nc(Nc3cccc(C(C)(C)C)c3)ncc12)N(C)C

BIRTHDAY: 2018-11-19T08:12:00.379105
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C31H39NO

SMILES: CC(C)(C)c1ccc(-c2cccc(C(=O)Nc3ccccc3C(C)(C)C)c2C(C)(C)C)cc1

BIRTHDAY: 2018-11-19T08:12:00.387487
ATC: C02K
- CARDIOVASCULAR SYSTEM
- ANTIHYPERTENSIVES
- OTHER ANTIHYPERTENSIVES
Synthesis Plan
FORMULA:C26H29N7O4

SMILES: COc1cc(NC(=O)c2ccc3cnc(Nc4ccc(OCCCN5CCOCC5)cc4)nc3c2)[nH]n1

BIRTHDAY: 2018-11-19T08:12:00.398964
ATC: N06A
- NERVOUS SYSTEM
- PSYCHOANALEPTICS
- ANTIDEPRESSANTS
Synthesis Plan
FORMULA:C23H23N5O2

SMILES: NC(=O)N1c2cccc(c2)CNCC=CCOCc2cccc(c2)-c2ccnc1n2

BIRTHDAY: 2018-11-19T08:12:00.408975
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C27H27FN2O3

SMILES: O=C(NCC1(O)CCCCC1)c1ccc(NC(=O)c2cccc(-c3ccc(F)cc3)c2)cc1

BIRTHDAY: 2018-11-19T08:12:00.418411
ATC: A03F
- ALIMENTARY TRACT AND METABOLISM
- DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS
- PROPULSIVES
Synthesis Plan
FORMULA:C30H35N5O2

SMILES: Cc1cccc(OC(C)(C)N(C)C)c1Nc1ncnc2c(-c3ccccc3C(=O)NC(C)C)cccc12

BIRTHDAY: 2018-11-19T08:12:00.428682
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C30H36N2O2

SMILES: CC(C)(C)CCNC(=O)c1ccc(NC(=O)c2ccc(-c3ccc(C(C)(C)C)cc3)cc2)cc1

BIRTHDAY: 2018-11-19T08:12:00.437294
ATC: N06A
- NERVOUS SYSTEM
- PSYCHOANALEPTICS
- ANTIDEPRESSANTS
Synthesis Plan
FORMULA:C29H33N5O

SMILES: C[C@@H](NC(=O)c1ccccc1-c1cccc2nc(Nc3ccccc3C(C)(C)C)ncc12)N(C)C

BIRTHDAY: 2018-11-19T08:12:00.447201
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C30H33N5O2

SMILES: Cc1cc(Nc2ncc3cc(-c4cccc(C(=O)NC5CC5)c4)ccc3n2)ccc1OCCCN(C)C

BIRTHDAY: 2018-11-19T08:12:00.457648
ATC: A10B
- ALIMENTARY TRACT AND METABOLISM
- DRUGS USED IN DIABETES
- BLOOD GLUCOSE LOWERING DRUGS, EXCL. INSULINS
Synthesis Plan
FORMULA:C40H41N5O2

SMILES: CN1CC=CCCOc2cccc(c2)-c2ccnc(n2)Nc2cc(cc(-c3ccc(NC(=O)c4cccc(C(C)(C)C)c4)cc3)c2)C1

BIRTHDAY: 2018-11-19T08:12:00.470041
ATC: C09C
- CARDIOVASCULAR SYSTEM
- AGENTS ACTING ON THE RENIN-ANGIOTENSIN SYSTEM
- ANGIOTENSIN II ANTAGONISTS, PLAIN
Synthesis Plan
FORMULA:C22H18N4O3

SMILES: CNC(=O)c1ccc(-c2ccc3nc(Nc4c(O)cccc4O)ncc3c2)cc1

BIRTHDAY: 2018-11-19T08:12:00.479223
ATC: M01A
- MUSCULO-SKELETAL SYSTEM
- ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS
- ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS
Synthesis Plan
FORMULA:C30H45N5O4

SMILES: COc1ccccc1CC(=O)Nc1cn(CC(=O)N[C@@H]2ON=CCC2(C(C)(C)C)C(C)(C)C)nc1C(C)(C)C

BIRTHDAY: 2018-11-19T08:12:00.499789
ATC: A16A
- ALIMENTARY TRACT AND METABOLISM
- OTHER ALIMENTARY TRACT AND METABOLISM PRODUCTS
- OTHER ALIMENTARY TRACT AND METABOLISM PRODUCTS
Synthesis Plan
FORMULA:C21H24N4O

SMILES: N[C@H]1[C@H]2C[C@H]3C[C@](c4ccc(NC(=O)Nc5ccccn5)cc4)(C2)C[C@H]31

BIRTHDAY: 2018-11-19T08:12:00.519243
ATC: P01B
- ANTIPARASITIC PRODUCTS, INSECTICIDES AND REPELLENTS
- ANTIPROTOZOALS
- ANTIMALARIALS
Synthesis Plan
FORMULA:C19H22OS2

SMILES: CC(C)(C)c1cccc([C@@]23C=CC=C[C@]2(O)SC=CSC3)c1

BIRTHDAY: 2018-11-19T08:12:00.526659
ATC: N04B
- NERVOUS SYSTEM
- ANTI-PARKINSON DRUGS
- DOPAMINERGIC AGENTS
Synthesis Plan
FORMULA:C26H25F3N2O2

SMILES: Cc1c(NC(=O)c2cccc(C(C)(C)C)c2)cccc1C(=O)Nc1ccccc1C(F)(F)F

BIRTHDAY: 2018-11-19T08:12:00.536238
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C22H18N4O3

SMILES: CNC(=O)c1ccccc1-c1cccc2nc(Nc3c(O)cccc3O)ncc12

BIRTHDAY: 2018-11-19T08:12:00.545640
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C27H31NO

SMILES: CC(C)(C)c1ccc(NC(=O)c2ccc(-c3ccccc3C(C)(C)C)cc2)cc1

BIRTHDAY: 2018-11-19T08:12:00.553164
ATC: C02K
- CARDIOVASCULAR SYSTEM
- ANTIHYPERTENSIVES
- OTHER ANTIHYPERTENSIVES
Synthesis Plan
FORMULA:C32H41N3O2

SMILES: CC(C)c1cccc(-c2cccc(C(=O)Nc3cccc(C(=O)NC(C)(C)N(C)C)c3)c2)c1C(C)(C)C

BIRTHDAY: 2018-11-19T08:12:00.562799
ATC: C03C
- CARDIOVASCULAR SYSTEM
- DIURETICS
- HIGH-CEILING DIURETICS
Synthesis Plan
FORMULA:C27H28FN3O3

SMILES: O=C(Nc1ccccc1C(=O)NCCCN1CCOCC1)c1ccc(-c2ccccc2F)cc1

BIRTHDAY: 2018-11-19T08:12:00.573107
ATC: N01B
- NERVOUS SYSTEM
- ANESTHETICS
- ANESTHETICS, LOCAL
Synthesis Plan
FORMULA:C26H31FN4O3

SMILES: COc1ccc(CC(=O)Nc2cc(C(C)(C)C)nn2CC(=O)N[C@@H](C)c2ccc(F)cc2)cc1

BIRTHDAY: 2018-11-30T17:22:51.306048
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C32H28FN3O3

SMILES: O=C(Cc1ccccc1)NC1(CNC(=O)c2ccccc2NC(=O)c2ccccc2-c2cccc(F)c2)CC1

BIRTHDAY: 2018-11-30T17:22:51.346957
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C30H36N2O2

SMILES: C[C@H](NC(=O)c1cccc(NC(=O)c2ccccc2-c2cccc(C(C)(C)C)c2)c1)C(C)(C)C

BIRTHDAY: 2018-11-30T17:22:51.355924
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C29H35N3O2

SMILES: CN(C)CCCNC(=O)c1ccc(NC(=O)c2ccccc2-c2ccc(C(C)(C)C)cc2)cc1

BIRTHDAY: 2018-11-30T17:22:51.421000
ATC: C03X
- CARDIOVASCULAR SYSTEM
- DIURETICS
- OTHER DIURETICS
Synthesis Plan
FORMULA:C32H33NO2

SMILES: CC(C)(C)c1ccccc1-c1cccc(C(=O)Nc2ccccc2[C@@H]2[C@@H]3C=C[C@@H]4[C@@H]2OC[C@@H]4C3)c1

BIRTHDAY: 2018-11-30T17:22:51.448522
ATC: C02K
- CARDIOVASCULAR SYSTEM
- ANTIHYPERTENSIVES
- OTHER ANTIHYPERTENSIVES
Synthesis Plan
FORMULA:C30H35N5O2

SMILES: Cc1cc(Nc2ncc3cc(-c4ccc(C(=O)NC(C)C)cc4)ccc3n2)ccc1OCCCN(C)C

BIRTHDAY: 2018-11-30T17:22:51.458510
ATC: A10B
- ALIMENTARY TRACT AND METABOLISM
- DRUGS USED IN DIABETES
- BLOOD GLUCOSE LOWERING DRUGS, EXCL. INSULINS
Synthesis Plan
FORMULA:C26H27N5O

SMILES: COc1ccccc1-c1ccc2c(Nc3ccc(N4CCN(C)CC4)cc3)ncnc2c1

BIRTHDAY: 2018-11-30T17:22:51.467650
ATC: N05A
- NERVOUS SYSTEM
- PSYCHOLEPTICS
- ANTIPSYCHOTICS
Synthesis Plan
FORMULA:C25H25N5O

SMILES: COc1ccccc1-c1ccc2cnc(Nc3ccc(N4CCNCC4)cc3)nc2c1

BIRTHDAY: 2018-11-30T17:22:51.476761
ATC: C08D
- CARDIOVASCULAR SYSTEM
- CALCIUM CHANNEL BLOCKERS
- SELECTIVE CALCIUM CHANNEL BLOCKERS WITH DIRECT CARDIAC EFFECTS
Synthesis Plan
FORMULA:C26H32N4O3

SMILES: COc1cccc(CC(=O)Nc2cc(C(C)(C)C)n(CC(=O)N[C@@H](C)c3ccccc3)n2)c1

BIRTHDAY: 2018-11-30T17:22:51.486560
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C26H23N3O3S

SMILES: COc1cccc(-c2ccc3c(c2)-c2c(cnn2C(=O)Nc2ccccc2OC)S[C@H]3C)c1

BIRTHDAY: 2018-12-02T16:05:59.700786
ATC: V08C
- VARIOUS
- CONTRAST MEDIA
- MAGNETIC RESONANCE IMAGING CONTRAST MEDIA
Synthesis Plan
FORMULA:C32H31N7O4S

SMILES: CNC(=O)c1ccncc1Oc1cccc2oc(N3CCOC=C4CNCC(=N4)c4cccc5c4SN(CC3)C53CC3)nc12

BIRTHDAY: 2018-12-02T16:05:59.734497
ATC: P01B
- ANTIPARASITIC PRODUCTS, INSECTICIDES AND REPELLENTS
- ANTIPROTOZOALS
- ANTIMALARIALS
Synthesis Plan
FORMULA:C18H13F3N4O2S

SMILES: O=C(Nc1cccc(C(=O)Nc2cscn2)c1)Nc1cccc(C(F)(F)F)c1

BIRTHDAY: 2018-12-02T16:05:59.754266
ATC: D10A
- DERMATOLOGICALS
- ANTI-ACNE PREPARATIONS
- ANTI-ACNE PREPARATIONS FOR TOPICAL USE
Synthesis Plan
FORMULA:C29H33N5O

SMILES: C[C@H](NC(=O)c1ccccc1-c1cccc2nc(Nc3ccccc3C(C)(C)C)ncc12)N(C)C

BIRTHDAY: 2018-12-02T16:05:59.775878
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C22H18ClN5O4

SMILES: CNC(=O)c1cc(Oc2cccc3oc(Nc4ccc(Cl)c(C(=O)NC)c4)nc23)ccn1

BIRTHDAY: 2018-12-02T16:05:59.786512
ATC: L04A
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- IMMUNOSUPPRESSANTS
- IMMUNOSUPPRESSANTS
Synthesis Plan
FORMULA:C22H22FN

SMILES: Fc1ccccc1-c1ccc(C2=CN(CC3CC3)CCC=C2)cc1

BIRTHDAY: 2018-12-02T16:05:59.793577
ATC: P03B
- ANTIPARASITIC PRODUCTS, INSECTICIDES AND REPELLENTS
- ECTOPARASITICIDES, INCL. SCABICIDES, INSECTICIDES AND REPELLENTS
- INSECTICIDES AND REPELLENTS
Synthesis Plan
FORMULA:C24H22F3NO3

SMILES: COc1ccc(CCNC(=O)c2ccc(-c3ccc(C(F)(F)F)cc3)cc2)cc1OC

BIRTHDAY: 2018-12-02T16:05:59.802695
ATC: N06A
- NERVOUS SYSTEM
- PSYCHOANALEPTICS
- ANTIDEPRESSANTS
Synthesis Plan
FORMULA:C20H28N5O3Ru

SMILES: COc1ccccc1[CH-]C(=O)Nc1c(C(C)(C)C)cnn1C[C@@H]1COCNN1.[Ru+]

BIRTHDAY: 2018-12-02T16:05:59.822347
ATC: G03X
- GENITO URINARY SYSTEM AND SEX HORMONES
- SEX HORMONES AND MODULATORS OF THE GENITAL SYSTEM
- OTHER SEX HORMONES AND MODULATORS OF THE GENITAL SYSTEM
Synthesis Plan
FORMULA:C28H28N4O

SMILES: CC(C)(C)c1ccc(Nc2ncnc3ccc(-c4ccc(C(=O)NC5CC5)cc4)cc23)cc1

BIRTHDAY: 2018-12-02T16:05:59.831580
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C32H43NO5

SMILES: COC(=O)[C@@H]1CCC[C@@H](c2ccc(C(=O)NC(C)(C)C)cc2)c2ccc(cc2)C[C@H](C)CC[C@H]1C(=O)OC

BIRTHDAY: 2018-12-02T16:05:59.866202
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C28H32N2O2

SMILES: CC(C)(C)c1ccc(NC(=O)c2ccccc2NC(=O)c2ccc(C(C)(C)C)cc2)cc1

BIRTHDAY: 2018-12-03T10:42:21.337275
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C26H27N5O

SMILES: COc1ccccc1-c1ccc2ncnc(Nc3ccc(N4CCN(C)CC4)cc3)c2c1

BIRTHDAY: 2018-12-03T10:42:21.366953
ATC: N05A
- NERVOUS SYSTEM
- PSYCHOLEPTICS
- ANTIPSYCHOTICS
Synthesis Plan
FORMULA:C29H27F4N3O3

SMILES: C[C@H](C(=O)N[C@H](CNC(=O)c1cccc(NC(=O)c2cccc(-c3cccc(F)c3)c2)c1)C1CC1)C(F)(F)F

BIRTHDAY: 2018-12-03T10:42:21.387873
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C25H24FN3O2

SMILES: NC1(CNC(=O)c2cccc(NC(=O)c3cccc(-c4cccc(F)c4)c3)c2)CCC1

BIRTHDAY: 2018-12-03T10:42:21.397380
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C30H36N2O2

SMILES: C[C@H](NC(=O)c1ccccc1NC(=O)c1ccccc1-c1cccc(C(C)(C)C)c1)C(C)(C)C

BIRTHDAY: 2018-12-03T10:42:21.429165
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C28H35N7O

SMILES: CNC(=O)c1ccccc1-c1cccc(CNc2nc(NCC(C)(C)C)c3c(ncn3C(C)C)n2)c1

BIRTHDAY: 2018-12-03T10:42:21.458613
ATC: C03C
- CARDIOVASCULAR SYSTEM
- DIURETICS
- HIGH-CEILING DIURETICS
Synthesis Plan
FORMULA:C25H23F3N4O3

SMILES: CNC(=O)c1cccc(CNC(=O)c2ccc(CNC(=O)Nc3cccc(C(F)(F)F)c3)cc2)c1

BIRTHDAY: 2018-12-03T10:42:21.518672
ATC: M04A
- MUSCULO-SKELETAL SYSTEM
- ANTIGOUT PREPARATIONS
- ANTIGOUT PREPARATIONS
Synthesis Plan
FORMULA:C39H31N5O2

SMILES: COc1ccccc1-c1ccc(C(=O)Nc2ccc(-c3cnc4nc3Nc3cccc(c3)C=Cc3cc(C)cc(c3)N4)cc2)cc1

BIRTHDAY: 2018-12-03T19:10:47.107678
ATC: P01A
- ANTIPARASITIC PRODUCTS, INSECTICIDES AND REPELLENTS
- ANTIPROTOZOALS
- AGENTS AGAINST AMOEBIASIS AND OTHER PROTOZOAL DISEASES
Synthesis Plan
FORMULA:C29H22F3N3O3

SMILES: CNC(=O)c1ccccc1-c1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1

BIRTHDAY: 2018-12-03T19:10:47.140049
ATC: V09C
- VARIOUS
- DIAGNOSTIC RADIOPHARMACEUTICALS
- RENAL SYSTEM
Synthesis Plan
FORMULA:C25H20F4N4O

SMILES: Fc1cccc(C(F)(F)F)c1-c1ccc2cnc(Nc3ccc(N4CCOCC4)cc3)nc2c1

BIRTHDAY: 2018-12-03T19:10:47.173362
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C27H27N5O2

SMILES: COc1ccc(-c2ccc3c(Nc4ccc(N5CCN(C(C)=O)CC5)cc4)ncnc3c2)cc1

BIRTHDAY: 2018-12-03T19:10:47.183294
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C27H28N2O4

SMILES: CC(C)(C)c1ccc(-c2ccc(C(=O)Nc3ccccc3C(=O)NCCC(=O)O)cc2)cc1

BIRTHDAY: 2018-12-03T19:10:47.193159
ATC: C03B
- CARDIOVASCULAR SYSTEM
- DIURETICS
- LOW-CEILING DIURETICS, EXCL. THIAZIDES
Synthesis Plan
FORMULA:C26H32N4O3

SMILES: COc1ccccc1CC(=O)Nc1cn(CC(=O)Nc2ccc(C)c(C)c2)nc1C(C)(C)C

BIRTHDAY: 2018-12-03T19:10:47.202927
ATC: H05B
- SYSTEMIC HORMONAL PREPARATIONS, EXCL. SEX HORMONES AND INSULINS
- CALCIUM HOMEOSTASIS
- ANTI-PARATHYROID AGENTS
Synthesis Plan
FORMULA:C20H22N6O3

SMILES: CC(=O)N[C@H]1N=C(c2ccc(-c3cccc(C(=O)NCCCN=O)c3)cc2)NN1

BIRTHDAY: 2018-12-03T19:10:47.212708
ATC: C10A
- CARDIOVASCULAR SYSTEM
- LIPID MODIFYING AGENTS
- LIPID MODIFYING AGENTS, PLAIN
Synthesis Plan
FORMULA:C26H31FN4O3

SMILES: COc1cccc(CC(=O)Nc2cc(C(C)(C)C)n(CC(=O)N[C@@H](C)c3cccc(F)c3)n2)c1

BIRTHDAY: 2018-12-03T19:10:47.232731
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C29H27F4N3O3

SMILES: C[C@H](C(=O)N[C@H](CNC(=O)c1ccccc1NC(=O)c1ccccc1-c1cccc(F)c1)C1CC1)C(F)(F)F

BIRTHDAY: 2018-12-03T19:10:47.257378
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C29H33N5O

SMILES: CN(C)CCNC(=O)c1cccc(-c2ccc3ncnc(Nc4ccc(C(C)(C)C)cc4)c3c2)c1

BIRTHDAY: 2018-12-03T19:10:47.278908
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C28H28N4O

SMILES: CC(C)(C)c1ccccc1Nc1ncc2c(-c3ccccc3C(=O)NC3CC3)cccc2n1

BIRTHDAY: 2018-12-01T22:29:51.575525
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C29H22F3N3O3

SMILES: CNC(=O)c1ccccc1NC(=O)c1ccccc1-c1ccccc1C(=O)Nc1ccc(C(F)(F)F)cc1

BIRTHDAY: 2018-12-01T22:29:51.586879
ATC: D11A
- DERMATOLOGICALS
- OTHER DERMATOLOGICAL PREPARATIONS
- OTHER DERMATOLOGICAL PREPARATIONS
Synthesis Plan
FORMULA:C27H27N5O2

SMILES: COc1ccc(-c2ccc3ncnc(Nc4ccc(N5CCN(C(C)=O)CC5)cc4)c3c2)cc1

BIRTHDAY: 2018-12-01T22:29:51.597022
ATC: D11A
- DERMATOLOGICALS
- OTHER DERMATOLOGICAL PREPARATIONS
- OTHER DERMATOLOGICAL PREPARATIONS
Synthesis Plan
FORMULA:C17H20N6O3

SMILES: COc1ccc(CCNC(=O)c2cnn(C)c2-c2nc(=O)[nH]n2C)cc1

BIRTHDAY: 2018-12-01T22:29:51.616072
ATC: N05B
- NERVOUS SYSTEM
- PSYCHOLEPTICS
- ANXIOLYTICS
Synthesis Plan
FORMULA:C25H26FN3O2

SMILES: CN(C)C(C)(C)NC(=O)c1ccc(NC(=O)c2cccc(-c3cccc(F)c3)c2)cc1

BIRTHDAY: 2018-12-01T22:29:51.635753
ATC: L02A
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ENDOCRINE THERAPY
- HORMONES AND RELATED AGENTS
Synthesis Plan
FORMULA:C25H26FN3O2

SMILES: CN(C)CCCNC(=O)c1cccc(NC(=O)c2ccc(-c3ccccc3F)cc2)c1

BIRTHDAY: 2018-12-01T22:29:51.644668
ATC: C10A
- CARDIOVASCULAR SYSTEM
- LIPID MODIFYING AGENTS
- LIPID MODIFYING AGENTS, PLAIN
Synthesis Plan
FORMULA:C22H18ClN5O4

SMILES: CNC(=O)c1cc(Oc2ccc3nc(Nc4c(Cl)cccc4C(=O)NC)oc3c2)ccn1

BIRTHDAY: 2018-12-01T22:29:51.655346
ATC: S01X
- SENSORY ORGANS
- OPHTHALMOLOGICALS
- OTHER OPHTHALMOLOGICALS
Synthesis Plan
FORMULA:C27H31NO

SMILES: CC(C)(C)c1cccc(-c2ccccc2C(=O)Nc2ccccc2C(C)(C)C)c1

BIRTHDAY: 2018-12-01T22:29:51.671682
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C36H37ClN8O4S2

SMILES: CNC(=O)c1ccc(Oc2ccc3oc(Nc4ccc(C5=N[C@H]6C=NCC=NCCO[C@@H](C=CCCSSC6)CC=NC5)c(Cl)c4)nc3c2)nc1

BIRTHDAY: 2018-12-01T22:29:51.687679
ATC: S01B
- SENSORY ORGANS
- OPHTHALMOLOGICALS
- ANTIINFLAMMATORY AGENTS
Synthesis Plan
FORMULA:C25H23F3N2O2

SMILES: CC(C)(C)c1cccc(C(=O)Nc2cccc(C(=O)Nc3ccccc3C(F)(F)F)c2)c1

BIRTHDAY: 2018-12-01T22:29:51.727699
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan