matter.farm

Computer-generated molecule database for public drug discovery. About this project.

These compounds may interact with:

Insulin-like growth factor 1 receptor

Potentially involved in: degenerative disc disease; gout; kidney cancer; carcinoma; liver cancer; cancer; diabetes mellitus; hyperglycemia; silver-russell syndrome; hyperinsulinism; graves' disease; obesity; alzheimer's disease; anxiety; neoplastic cell transformation; endometrial neoplasms; fetal growth retardation; growth disorders; infant, small for gestational age; language delay

Disease data sourced from Pharos.

Inhibitor

FORMULA:C28H34N4O

SMILES: CC(=O)Nc1cc(-c2ccnc(Nc3ccc(C(C)(C)C)cc3)n2)ccc1C1CC(C)(C)C1

BIRTHDAY: 2018-12-01T14:11:07.166088
ATC: M03A
- MUSCULO-SKELETAL SYSTEM
- MUSCLE RELAXANTS
- MUSCLE RELAXANTS, PERIPHERALLY ACTING AGENTS
Synthesis Plan
FORMULA:C17H17N5O2S

SMILES: COc1ccc(OC)c(Nc2ncc3c(n2)-c2nc(N)sc2CC3)c1

BIRTHDAY: 2018-12-01T14:11:07.175404
ATC: C02C
- CARDIOVASCULAR SYSTEM
- ANTIHYPERTENSIVES
- ANTIADRENERGIC AGENTS, PERIPHERALLY ACTING
Synthesis Plan
FORMULA:C26H28N6O

SMILES: Nc1ncc2c(n1)c(-c1ccccc1OCc1ccccc1)cn2C1([C@]2(N)CCN2)CCC1

BIRTHDAY: 2018-12-01T14:11:07.185908
ATC: J05A
- ANTIINFECTIVES FOR SYSTEMIC USE
- ANTIVIRALS FOR SYSTEMIC USE
- DIRECT ACTING ANTIVIRALS
Synthesis Plan
FORMULA:C27H24FN3O4S

SMILES: NS(=O)(=O)c1cccc(-c2ccccc2NC(=O)[C@@]23C=C[C@](NC(=O)c4ccc(F)cc4)(CC2)C3)c1

BIRTHDAY: 2018-12-01T14:11:07.196939
ATC: N05A
- NERVOUS SYSTEM
- PSYCHOLEPTICS
- ANTIPSYCHOTICS
Synthesis Plan
FORMULA:C28H27N5O2

SMILES: CC(C)(NC(=O)c1ccc(NC(=O)c2ccccn2)cc1)N(Cc1ccccc1)c1ccccn1

BIRTHDAY: 2018-12-01T14:11:07.206942
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C25H34N8O

SMILES: CC(=O)N1CCN(c2ccc(Nc3nccc(-c4cn(CCN)nc4CC(C)C)n3)cc2)CC1

BIRTHDAY: 2018-12-01T14:11:07.217291
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C23H23FN4O

SMILES: N[C@H]1C=NC=C2NC(c3ccccc3OCc3cccc(F)c3)=C(C3CCC3)N21

BIRTHDAY: 2018-12-01T14:11:07.226898
ATC: A11H
- ALIMENTARY TRACT AND METABOLISM
- VITAMINS
- OTHER PLAIN VITAMIN PREPARATIONS
Synthesis Plan
FORMULA:C26H32N8O2

SMILES: COc1ccc(N2C=CNCCCCCC2)cc1Nc1ncc2c(n1)-c1c(c(C(N)=O)nn1C)CC2

BIRTHDAY: 2018-12-01T14:11:07.238401
ATC: N06D
- NERVOUS SYSTEM
- PSYCHOANALEPTICS
- ANTI-DEMENTIA DRUGS
Synthesis Plan
FORMULA:C23H22F3N5O2S

SMILES: CN1C=CN=C2NC(C3CCC3)=N[C@]21c1ccc(S(=O)(=O)Nc2ccccc2C(F)(F)F)cc1

BIRTHDAY: 2018-12-01T14:11:07.250926
ATC: P01B
- ANTIPARASITIC PRODUCTS, INSECTICIDES AND REPELLENTS
- ANTIPROTOZOALS
- ANTIMALARIALS
Synthesis Plan
FORMULA:C17H17N5O2S

SMILES: COc1ccc(Nc2ncc3c(n2)-c2nc(N)sc2CC3)cc1OC

BIRTHDAY: 2018-12-01T14:11:07.260462
ATC: C08D
- CARDIOVASCULAR SYSTEM
- CALCIUM CHANNEL BLOCKERS
- SELECTIVE CALCIUM CHANNEL BLOCKERS WITH DIRECT CARDIAC EFFECTS
Synthesis Plan
FORMULA:C23H22F3N5O2S

SMILES: N[C@@]12C=NC=CN1C(C1CCC1)=C(c1ccccc1S(=O)(=O)Nc1cccc(C(F)(F)F)c1)N2

BIRTHDAY: 2018-12-01T14:11:07.272072
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C25H30N6O2S

SMILES: CN(C)Cc1ccc(NS(=O)(=O)c2ccc(C3=NC4=NC=CN(C)[C@@]4(C4CCC4)N3)cc2)cc1

BIRTHDAY: 2018-12-01T14:11:07.283115
ATC: D01A
- DERMATOLOGICALS
- ANTIFUNGALS FOR DERMATOLOGICAL USE
- ANTIFUNGALS FOR TOPICAL USE
Synthesis Plan
FORMULA:C21H26N10O2

SMILES: COc1cccc(Nc2ncc3c(n2)CC=C2NN=C(C(N)=O)[C@@]23N)c1N1CCNC[C@H]1N

BIRTHDAY: 2018-12-01T14:11:07.294935
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C22H20F3N5O2S

SMILES: C=CN[C@]12C=NC=CN1C(C)=C(c1ccccc1S(=O)(=O)Nc1ccccc1C(F)(F)F)N2

BIRTHDAY: 2018-12-01T14:11:07.307207
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C24H28N8O3

SMILES: COc1ccc(N2C[C@@H]3COC[C@@H](C2)N3)cc1Nc1ncc2c(n1)-c1c(c(C(N)=O)nn1C)CC2

BIRTHDAY: 2018-12-01T14:11:07.319310
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C23H23FN4O

SMILES: CN1C=CN=C2NC(c3ccc(OCc4ccccc4F)cc3)=N[C@@]21C1CCC1

BIRTHDAY: 2018-12-01T14:11:07.328841
ATC: B02A
- BLOOD AND BLOOD FORMING ORGANS
- ANTIHEMORRHAGICS
- ANTIFIBRINOLYTICS
Synthesis Plan
FORMULA:C28H34N4O

SMILES: CC(=O)Nc1c(-c2ncncc2Nc2ccccc2C(C)(C)C)cccc1[C@H]1CCC1(C)C

BIRTHDAY: 2018-12-01T14:11:07.339758
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C30H28N6O4

SMILES: CC(C)c1ccccc1NC(=O)c1ccccc1[C@@]1(N)C=NC(=O)[C@@]2(C(=O)O)C=CN=C(Nc3ccccc3)N12

BIRTHDAY: 2018-12-01T14:11:07.353274
ATC: A11H
- ALIMENTARY TRACT AND METABOLISM
- VITAMINS
- OTHER PLAIN VITAMIN PREPARATIONS
Synthesis Plan
FORMULA:C25H22F3N7O2S

SMILES: C[C@@]12N=C(c3ccccc3S(=O)(=O)Nc3ccc(C(F)(F)F)cc3)NC1=NC(NCc1ccncc1)=CN2

BIRTHDAY: 2018-12-01T14:11:07.366356
ATC: C02B
- CARDIOVASCULAR SYSTEM
- ANTIHYPERTENSIVES
- ANTIADRENERGIC AGENTS, GANGLION-BLOCKING
Synthesis Plan
FORMULA:C23H24N4O4

SMILES: COc1cccc(C(=O)NCC(=O)O)c1Nc1cnc(-c2ccccc2C(C)C)nc1

BIRTHDAY: 2018-12-25T02:03:10.591071
ATC: C09C
- CARDIOVASCULAR SYSTEM
- AGENTS ACTING ON THE RENIN-ANGIOTENSIN SYSTEM
- ANGIOTENSIN II ANTAGONISTS, PLAIN
Synthesis Plan
FORMULA:C27H29N5O

SMILES: Nc1ncc2c(-c3cccc(OCc4ccccc4)c3)cn(C3CC(CN4CCC4)C3)c2n1

BIRTHDAY: 2018-12-25T02:03:10.601413
ATC: A11D
- ALIMENTARY TRACT AND METABOLISM
- VITAMINS
- VITAMIN B1, PLAIN AND IN COMBINATION WITH VITAMIN B6 AND B12
Synthesis Plan
FORMULA:C21H26N10O2

SMILES: COc1cccc(Nc2ncc3c(n2)CC=C2NN=C(C(N)=O)[C@]23N)c1N1CCNC[C@H]1N

BIRTHDAY: 2018-12-25T02:03:10.613885
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C23H23FN4O

SMILES: CN1C=CN=C2NC(c3ccc(OCc4ccccc4F)cc3)=N[C@]21C1CCC1

BIRTHDAY: 2018-12-25T02:03:10.623538
ATC: B02A
- BLOOD AND BLOOD FORMING ORGANS
- ANTIHEMORRHAGICS
- ANTIFIBRINOLYTICS
Synthesis Plan
FORMULA:C25H28N6O

SMILES: CC(C)Nc1ccncc1-n1c(=O)ccc2ncnc(Nc3cccc(C(C)(C)C)c3)c21

BIRTHDAY: 2018-12-25T02:03:10.633449
ATC: B03B
- BLOOD AND BLOOD FORMING ORGANS
- ANTIANEMIC PREPARATIONS
- VITAMIN B12 AND FOLIC ACID
Synthesis Plan
FORMULA:C20H18F3N5O2S

SMILES: CC1=C(c2ccccc2S(=O)(=O)Nc2cccc(C(F)(F)F)c2)NC2=CN=C[C@H](N)N21

BIRTHDAY: 2018-12-25T02:03:10.644569
ATC: D03A
- DERMATOLOGICALS
- PREPARATIONS FOR TREATMENT OF WOUNDS AND ULCERS
- CICATRIZANTS
Synthesis Plan
FORMULA:C23H27ClN8

SMILES: CC(C)Cc1cnn(C(C)(C)C)c1Nc1c(Cl)ncnc1Nc1cccc2nccnc12

BIRTHDAY: 2018-12-25T02:03:10.655941
ATC: B03B
- BLOOD AND BLOOD FORMING ORGANS
- ANTIANEMIC PREPARATIONS
- VITAMIN B12 AND FOLIC ACID
Synthesis Plan
FORMULA:C23H22F2N4O

SMILES: CN1C=CN=C2NC(c3cccc(OCc4ccc(F)cc4F)c3)=N[C@@]21C1CCC1

BIRTHDAY: 2018-12-25T02:03:10.665934
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C23H23FN4O

SMILES: CN1C=CN=C2NC(c3ccc(OCc4ccc(F)cc4)cc3)=N[C@]21C1CCC1

BIRTHDAY: 2018-12-25T02:03:10.676123
ATC: N06A
- NERVOUS SYSTEM
- PSYCHOANALEPTICS
- ANTIDEPRESSANTS
Synthesis Plan
FORMULA:C20H18F3N5O2S

SMILES: CC1=N[C@]2(c3ccc(S(=O)(=O)Nc4ccc(C(F)(F)F)cc4)cc3)C(=NC=CN2C)N1

BIRTHDAY: 2018-12-25T02:03:10.688544
ATC: C02C
- CARDIOVASCULAR SYSTEM
- ANTIHYPERTENSIVES
- ANTIADRENERGIC AGENTS, PERIPHERALLY ACTING
Synthesis Plan
FORMULA:C21H28N10O2

SMILES: COc1cc(Nc2ncc3c(n2)C[C@@]2(C(N)=O)C=NN[C@@]2(N)C3)ccc1N1CCNC[C@H]1N

BIRTHDAY: 2018-12-25T02:03:10.709478
ATC: H05A
- SYSTEMIC HORMONAL PREPARATIONS, EXCL. SEX HORMONES AND INSULINS
- CALCIUM HOMEOSTASIS
- PARATHYROID HORMONES AND ANALOGUES
Synthesis Plan
FORMULA:C28H34N4O

SMILES: CC(=O)Nc1cc(C2CC(C)(C)C2)ccc1-c1ccnc(Nc2ccc(C(C)(C)C)cc2)n1

BIRTHDAY: 2018-12-25T02:03:10.718569
ATC: C01D
- CARDIOVASCULAR SYSTEM
- CARDIAC THERAPY
- VASODILATORS USED IN CARDIAC DISEASES
Synthesis Plan
FORMULA:C21H18N4O4

SMILES: O=C(NCc1n[nH]c(=O)o1)c1cccc(NC(=O)c2cccc3c2C=CCC3)c1

BIRTHDAY: 2018-12-25T02:03:10.728269
ATC: P03B
- ANTIPARASITIC PRODUCTS, INSECTICIDES AND REPELLENTS
- ECTOPARASITICIDES, INCL. SCABICIDES, INSECTICIDES AND REPELLENTS
- INSECTICIDES AND REPELLENTS
Synthesis Plan
FORMULA:C27H26FN3O2

SMILES: CC(C)c1ccc(NC(=O)c2ccc(CN3C(=O)CN=C[C@H]3c3ccccc3F)cc2)cc1

BIRTHDAY: 2018-12-25T02:03:10.737877
ATC: D06A
- DERMATOLOGICALS
- ANTIBIOTICS AND CHEMOTHERAPEUTICS FOR DERMATOLOGICAL USE
- ANTIBIOTICS FOR TOPICAL USE
Synthesis Plan
FORMULA:C19H23ClN6

SMILES: Cc1cccc(CNc2ncnc(Cl)c2Nc2n[nH]cc2CC(C)C)c1

BIRTHDAY: 2018-12-25T02:03:10.746989
ATC: N06B
- NERVOUS SYSTEM
- PSYCHOANALEPTICS
- PSYCHOSTIMULANTS, AGENTS USED FOR ADHD AND NOOTROPICS
Synthesis Plan
FORMULA:C24H33ClN6

SMILES: Cc1ccc(CNc2ncnc(Cl)c2Nc2cn(CC(C)C)nc2CC(C)(C)C)cc1

BIRTHDAY: 2018-12-25T02:03:10.756567
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C24H22N2O4

SMILES: CC(C)c1ccc(NC(=O)c2ccc(C(=O)Nc3ccccc3C(=O)O)cc2)cc1

BIRTHDAY: 2018-12-25T02:03:10.765652
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C23H23FN4O

SMILES: CN1C=CN=C2N=C(c3ccc(OCc4ccc(F)cc4)cc3)N[C@]21C1CCC1

BIRTHDAY: 2018-12-25T02:03:10.775122
ATC: D01A
- DERMATOLOGICALS
- ANTIFUNGALS FOR DERMATOLOGICAL USE
- ANTIFUNGALS FOR TOPICAL USE
Synthesis Plan
FORMULA:C25H28N6O2

SMILES: COc1cccc(Nc2nc(-c3ccccc3C(C)C)nc3nc[nH]c23)c1N1CCOCC1

BIRTHDAY: 2018-12-03T02:39:14.264161
ATC: D11A
- DERMATOLOGICALS
- OTHER DERMATOLOGICAL PREPARATIONS
- OTHER DERMATOLOGICAL PREPARATIONS
Synthesis Plan
FORMULA:C23H23FN4O

SMILES: CN1C=CN=C2NC(c3cccc(OCc4ccc(F)cc4)c3)=N[C@@]21C1CCC1

BIRTHDAY: 2018-12-03T02:39:14.273875
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C23H22F3N5O2S

SMILES: CN1C=CN=C2N=C(C3CCC3)N[C@]21c1ccc(S(=O)(=O)Nc2ccccc2C(F)(F)F)cc1

BIRTHDAY: 2018-12-03T02:39:14.286347
ATC: J01D
- ANTIINFECTIVES FOR SYSTEMIC USE
- ANTIBACTERIALS FOR SYSTEMIC USE
- OTHER BETA-LACTAM ANTIBACTERIALS
Synthesis Plan
FORMULA:C23H23FN4O

SMILES: CN1C=CN=C2NC(c3ccc(OCc4ccc(F)cc4)cc3)=N[C@@]21C1CCC1

BIRTHDAY: 2018-12-03T02:39:14.295845
ATC: N06A
- NERVOUS SYSTEM
- PSYCHOANALEPTICS
- ANTIDEPRESSANTS
Synthesis Plan
FORMULA:C16H18O3

SMILES: C[C@@]12C=CC(O)=C[C@]13C=CC=C[C@H]3CC(=O)COC2

BIRTHDAY: 2018-12-03T02:39:14.302788
ATC: D11A
- DERMATOLOGICALS
- OTHER DERMATOLOGICAL PREPARATIONS
- OTHER DERMATOLOGICAL PREPARATIONS
Synthesis Plan
FORMULA:C26H23F3N6O2S

SMILES: CC1=C(c2ccccc2S(=O)(=O)Nc2ccccc2C(F)(F)F)N[C@]2(NCc3ccncc3)C=NC=CN12

BIRTHDAY: 2018-12-03T02:39:14.316368
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C17H17N5O2S

SMILES: COc1cccc(Nc2ncc3c(n2)CC=C2SC=N[C@]23N)c1OC

BIRTHDAY: 2018-12-03T02:39:14.334673
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C21H28N10O2

SMILES: COc1cccc(Nc2ncc3c(n2)C[C@]2(N)NN=C(C(N)=O)[C@H]2C3)c1N1CCNC[C@@H]1N

BIRTHDAY: 2018-12-03T02:39:14.346128
ATC: B03B
- BLOOD AND BLOOD FORMING ORGANS
- ANTIANEMIC PREPARATIONS
- VITAMIN B12 AND FOLIC ACID
Synthesis Plan
FORMULA:C24H22N2O4

SMILES: CC(C)c1ccccc1NC(=O)c1ccccc1C(=O)Nc1ccc(C(=O)O)cc1

BIRTHDAY: 2018-12-03T02:39:14.364328
ATC: P03B
- ANTIPARASITIC PRODUCTS, INSECTICIDES AND REPELLENTS
- ECTOPARASITICIDES, INCL. SCABICIDES, INSECTICIDES AND REPELLENTS
- INSECTICIDES AND REPELLENTS
Synthesis Plan
FORMULA:C29H35N7O

SMILES: CC(=O)N1CCN(c2ccccc2Nc2cnc(-c3c(CC(C)C)nn4c3[C@H]3C=C[C@@H](C3)C4)nc2)CC1

BIRTHDAY: 2018-12-03T02:39:14.375968
ATC: J05A
- ANTIINFECTIVES FOR SYSTEMIC USE
- ANTIVIRALS FOR SYSTEMIC USE
- DIRECT ACTING ANTIVIRALS
Synthesis Plan
FORMULA:C23H22F3N5O2S

SMILES: N[C@]12C=NC=CN1C(c1ccccc1S(=O)(=O)Nc1cccc(C(F)(F)F)c1)=C(C1CCC1)N2

BIRTHDAY: 2018-12-03T02:39:14.387769
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C17H19N5O2S

SMILES: COc1cccc(Nc2ncc3c(n2)C[C@H]2SC=N[C@]2(N)C3)c1OC

BIRTHDAY: 2018-12-03T02:39:14.396874
ATC: M01A
- MUSCULO-SKELETAL SYSTEM
- ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS
- ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS
Synthesis Plan
FORMULA:C20H18F3N5O2S

SMILES: CC1=N[C@@]2(c3ccc(S(=O)(=O)Nc4ccc(C(F)(F)F)cc4)cc3)C(=NC=CN2C)N1

BIRTHDAY: 2018-12-03T02:39:14.408307
ATC: C02C
- CARDIOVASCULAR SYSTEM
- ANTIHYPERTENSIVES
- ANTIADRENERGIC AGENTS, PERIPHERALLY ACTING
Synthesis Plan
FORMULA:C24H33ClN6

SMILES: Cc1ccccc1CNc1nc(Nc2cnn(CC(C)C)c2CC(C)(C)C)ncc1Cl

BIRTHDAY: 2018-12-03T02:39:14.418284
ATC: J01X
- ANTIINFECTIVES FOR SYSTEMIC USE
- ANTIBACTERIALS FOR SYSTEMIC USE
- OTHER ANTIBACTERIALS
Synthesis Plan
FORMULA:C26H28N6O

SMILES: Nc1ncnc2c(-c3ccccc3OCc3ccccc3)cn(C3([C@@]4(N)CCN4)CCC3)c12

BIRTHDAY: 2018-11-30T03:41:11.266058
ATC: J05A
- ANTIINFECTIVES FOR SYSTEMIC USE
- ANTIVIRALS FOR SYSTEMIC USE
- DIRECT ACTING ANTIVIRALS
Synthesis plan pending
FORMULA:C23H22F3N5O2S

SMILES: N[C@]12C=NC=CN1C(C1CCC1)=C(c1ccccc1S(=O)(=O)Nc1cccc(C(F)(F)F)c1)N2

BIRTHDAY: 2018-11-30T03:41:11.277568
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis plan pending
FORMULA:C19H14ClFN2O2S

SMILES: Cn1c2c(ncc1=O)SC[C@@](c1cccc(F)c1)(c1cccc(Cl)c1)O2

BIRTHDAY: 2018-11-30T03:41:11.286832
ATC: P01B
- ANTIPARASITIC PRODUCTS, INSECTICIDES AND REPELLENTS
- ANTIPROTOZOALS
- ANTIMALARIALS
Synthesis plan pending
FORMULA:C23H23FN4O

SMILES: N[C@]12C=NC=CN1C(C1CCC1)=C(c1ccccc1OCc1cccc(F)c1)N2

BIRTHDAY: 2018-11-30T03:41:11.296233
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis plan pending
FORMULA:C24H23N5O

SMILES: COc1ccccc1Nc1ncc2c(n1)-c1c(nn(C)c1Cc1ccccc1)CC2

BIRTHDAY: 2018-11-30T03:41:11.305792
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis plan pending
FORMULA:C25H24N6

SMILES: Cc1ccc(-n2nc(-c3ccc(C(C)C)cc3)cc2Nc2ncnc3[nH]ccc23)cc1

BIRTHDAY: 2018-11-30T03:41:11.337133
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis plan pending
FORMULA:C29H36ClN7O

SMILES: CC(C)CCCNc1ncc2c(n1)c(Nc1ccccc1Cl)nc1cc(C(=O)NCCCN(C)C)ccc12

BIRTHDAY: 2018-11-30T03:41:11.348031
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis plan pending
FORMULA:C27H29F3N6

SMILES: CC(C)Cc1ccccc1-c1cn[nH]c1Nc1c(Nc2ccccc2C(C)C)ncnc1C(F)(F)F

BIRTHDAY: 2018-11-30T03:41:11.361801
ATC: H01A
- SYSTEMIC HORMONAL PREPARATIONS, EXCL. SEX HORMONES AND INSULINS
- PITUITARY AND HYPOTHALAMIC HORMONES AND ANALOGUES
- ANTERIOR PITUITARY LOBE HORMONES AND ANALOGUES
Synthesis plan pending
FORMULA:C17H17N5O2S

SMILES: COc1cccc(Nc2ncnc3c2[C@@]2(N)N=CSC2=CC3)c1OC

BIRTHDAY: 2018-11-30T03:41:11.380767
ATC: N05A
- NERVOUS SYSTEM
- PSYCHOLEPTICS
- ANTIPSYCHOTICS
Synthesis plan pending
FORMULA:C27H21N3O4

SMILES: O=C(O)c1cccc(NC(=O)c2ccccc2NC(=O)c2ccccc2Nc2ccccc2)c1

BIRTHDAY: 2018-11-30T03:41:11.391269
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis plan pending
FORMULA:C21H28N10O2

SMILES: COc1cccc(Nc2ncnc3c2C[C@@H]2C(C(N)=O)=NN[C@@]2(N)C3)c1N1CCNC[C@H]1N

BIRTHDAY: 2018-11-30T03:41:11.403080
ATC: B06A
- BLOOD AND BLOOD FORMING ORGANS
- OTHER HEMATOLOGICAL AGENTS
- OTHER HEMATOLOGICAL AGENTS
Synthesis plan pending
FORMULA:C17H17N5O2S

SMILES: COc1cccc(Nc2ncnc3c2C=C[C@H]2SC=N[C@]32N)c1OC

BIRTHDAY: 2018-11-30T03:41:11.412164
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis plan pending
FORMULA:C23H22F3N5O2S

SMILES: N[C@@H]1C=NC=C2NC(c3ccccc3S(=O)(=O)Nc3cccc(C(F)(F)F)c3)=C(C3CCC3)N21

BIRTHDAY: 2018-11-30T03:41:11.423597
ATC: D03A
- DERMATOLOGICALS
- PREPARATIONS FOR TREATMENT OF WOUNDS AND ULCERS
- CICATRIZANTS
Synthesis plan pending
FORMULA:C30H33N3O3S

SMILES: C[C@]1(NC(=O)c2ccccc2NC(=O)[C@]2(Nc3ccccc3)SCC[C@H]3C=CC=C[C@H]32)C[C@H]2CC[C@H]1O2

BIRTHDAY: 2018-11-19T08:15:41.292464
ATC: N05B
- NERVOUS SYSTEM
- PSYCHOLEPTICS
- ANXIOLYTICS
Synthesis Plan
FORMULA:C23H23FN4O

SMILES: CN1C=CN=C2N=C(c3ccc(OCc4ccccc4F)cc3)N[C@]21C1CCC1

BIRTHDAY: 2018-11-19T08:15:41.302145
ATC: D01A
- DERMATOLOGICALS
- ANTIFUNGALS FOR DERMATOLOGICAL USE
- ANTIFUNGALS FOR TOPICAL USE
Synthesis Plan
FORMULA:C27H37N7O

SMILES: CC(C)Cc1c[nH]nc1Nc1nc(N[C@@H](CO)c2ccccc2)c2c(n1)[C@@H]1CC[C@H]2CN1C(C)C

BIRTHDAY: 2018-11-19T08:15:41.313973
ATC: C02A
- CARDIOVASCULAR SYSTEM
- ANTIHYPERTENSIVES
- ANTIADRENERGIC AGENTS, CENTRALLY ACTING
Synthesis Plan
FORMULA:C23H23FN4O

SMILES: N[C@@H]1C=NC=C2NC(c3ccccc3OCc3cccc(F)c3)=C(C3CCC3)N21

BIRTHDAY: 2018-11-19T08:15:41.323476
ATC: A11H
- ALIMENTARY TRACT AND METABOLISM
- VITAMINS
- OTHER PLAIN VITAMIN PREPARATIONS
Synthesis Plan
FORMULA:C37H41N9O2

SMILES: COc1ccccc1Nc1ncnc2c1C=C[C@]1(N)C=NN[C@@]21[C@H]1[C@H]2CCN1CCc1cccc(c1)Oc1cccc(c1)CNCCN2

BIRTHDAY: 2018-11-19T08:15:41.339628
ATC: R05D
- RESPIRATORY SYSTEM
- COUGH AND COLD PREPARATIONS
- COUGH SUPPRESSANTS, EXCL. COMBINATIONS WITH EXPECTORANTS
Synthesis Plan
FORMULA:C23H23FN4O

SMILES: N[C@@]12C=NC=CN1C(c1ccccc1OCc1cccc(F)c1)=C(C1CCC1)N2

BIRTHDAY: 2018-11-19T08:15:41.349273
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C27H32N4O4

SMILES: COc1cc(Nc2nccc(-c3ccc(C4CC(C)(C)C4)cc3NC(C)=O)n2)cc(OC)c1OC

BIRTHDAY: 2018-11-19T08:15:41.359575
ATC: C10A
- CARDIOVASCULAR SYSTEM
- LIPID MODIFYING AGENTS
- LIPID MODIFYING AGENTS, PLAIN
Synthesis Plan
FORMULA:C21H28N10O2

SMILES: COc1cc(Nc2ncc3c(n2)C[C@@]2(N)NN=C[C@@]2(C(N)=O)C3)ccc1N1CCNC[C@@H]1N

BIRTHDAY: 2018-11-19T08:15:41.371210
ATC: H05A
- SYSTEMIC HORMONAL PREPARATIONS, EXCL. SEX HORMONES AND INSULINS
- CALCIUM HOMEOSTASIS
- PARATHYROID HORMONES AND ANALOGUES
Synthesis Plan
FORMULA:C23H30N2O3

SMILES: CC1(C)CC[C@@H](Cc2ccc(-c3ccc(NCCCC(=O)O)nc3)cc2)CO1

BIRTHDAY: 2018-11-19T08:15:41.379524
ATC: D07A
- DERMATOLOGICALS
- CORTICOSTEROIDS, DERMATOLOGICAL PREPARATIONS
- CORTICOSTEROIDS, PLAIN
Synthesis Plan
FORMULA:C25H28ClN5O2

SMILES: CC(C)CC(=O)Nc1ccc(-c2cc(Nc3cccc(Cl)c3)nc(N3CCOCC3)n2)cc1

BIRTHDAY: 2018-11-19T08:15:41.389823
ATC: M01A
- MUSCULO-SKELETAL SYSTEM
- ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS
- ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS
Synthesis Plan
FORMULA:C23H19F3N2O2

SMILES: C[C@@H](NC(=O)c1cccc(NC(=O)c2cccc(C(F)(F)F)c2)c1)c1ccccc1

BIRTHDAY: 2018-11-19T08:15:41.399238
ATC: M03B
- MUSCULO-SKELETAL SYSTEM
- MUSCLE RELAXANTS
- MUSCLE RELAXANTS, CENTRALLY ACTING AGENTS
Synthesis Plan
FORMULA:C28H38N6O2

SMILES: CC(C)CC(=O)N[C@@H]1CCCCN1c1ccccc1Nc1ncc2c(n1)CC(=O)N(C1CCCC1)C2

BIRTHDAY: 2018-11-19T08:15:41.410021
ATC: P01B
- ANTIPARASITIC PRODUCTS, INSECTICIDES AND REPELLENTS
- ANTIPROTOZOALS
- ANTIMALARIALS
Synthesis Plan
FORMULA:C25H24N6

SMILES: Cc1ccccc1-n1nc(-c2ccc(C(C)C)cc2)cc1Nc1ncnc2[nH]ccc12

BIRTHDAY: 2018-11-19T08:15:41.419714
ATC: L04A
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- IMMUNOSUPPRESSANTS
- IMMUNOSUPPRESSANTS
Synthesis Plan
FORMULA:C23H23FN4O

SMILES: CN1C=CN=C2N=C(c3cccc(OCc4cccc(F)c4)c3)N[C@@]21C1CCC1

BIRTHDAY: 2018-11-19T08:15:41.429323
ATC: C03B
- CARDIOVASCULAR SYSTEM
- DIURETICS
- LOW-CEILING DIURETICS, EXCL. THIAZIDES
Synthesis Plan
FORMULA:C20H14N2O3

SMILES: N#Cc1ccccc1-c1ccn(Cc2cccc3c2OCO3)c(=O)c1

BIRTHDAY: 2018-11-19T08:15:41.437613
ATC: J05A
- ANTIINFECTIVES FOR SYSTEMIC USE
- ANTIVIRALS FOR SYSTEMIC USE
- DIRECT ACTING ANTIVIRALS
Synthesis Plan
FORMULA:C17H14F3N7O3

SMILES: COc1cccc(C(F)(F)F)c1Nc1cncnc1-c1[nH]nc2c1C=NNC2(O)O

BIRTHDAY: 2018-11-19T08:15:41.449166
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C23H22F3N5O2S

SMILES: CN1C=CN=C2NC(C3CCC3)=N[C@@]21c1ccc(S(=O)(=O)Nc2ccccc2C(F)(F)F)cc1

BIRTHDAY: 2018-11-19T08:15:41.461649
ATC: P01B
- ANTIPARASITIC PRODUCTS, INSECTICIDES AND REPELLENTS
- ANTIPROTOZOALS
- ANTIMALARIALS
Synthesis Plan
FORMULA:C26H27F3N6

SMILES: CC(C)c1ccc(Nc2ncnc(C(F)(F)F)c2Nc2[nH]ncc2-c2cccc(C(C)C)c2)cc1

BIRTHDAY: 2018-11-19T08:15:41.472572
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C28H27N5O2

SMILES: CC(C)(NC(=O)c1cccc(NC(=O)c2ccccn2)c1)N(Cc1ccccc1)c1ccncc1

BIRTHDAY: 2018-11-19T08:15:41.482762
ATC: A04A
- ALIMENTARY TRACT AND METABOLISM
- ANTIEMETICS AND ANTINAUSEANTS
- ANTIEMETICS AND ANTINAUSEANTS
Synthesis Plan
FORMULA:C25H28N6O

SMILES: CC(C)Nc1cccc(-n2c(=O)ccc3cnc(Nc4ccc(C(C)(C)C)cc4)nc32)n1

BIRTHDAY: 2018-11-19T08:15:41.492388
ATC: L01B
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- ANTIMETABOLITES
Synthesis Plan
FORMULA:C32H33FN6O2

SMILES: CC(C)NC1=CN2[C@](c3cccc(F)c3)(N=C1)C(=O)N=C[C@@]2(N)c1ccccc1C(=O)Nc1ccccc1C(C)C

BIRTHDAY: 2018-11-19T08:15:41.524788
ATC: C10A
- CARDIOVASCULAR SYSTEM
- LIPID MODIFYING AGENTS
- LIPID MODIFYING AGENTS, PLAIN
Synthesis Plan
FORMULA:C36H36N2O3

SMILES: CC(C)c1cccc(NC(=O)c2ccccc2C(=O)Nc2ccc([C@@]34O[C@@H]5[C@H]6[C@@H]3[C@@H]3[C@H]7[C@@H]4[C@H]5[C@H]([C@@H]36)C7(C)C)cc2)c1

BIRTHDAY: 2018-11-19T08:15:41.536281
ATC: C10A
- CARDIOVASCULAR SYSTEM
- LIPID MODIFYING AGENTS
- LIPID MODIFYING AGENTS, PLAIN
Synthesis Plan
FORMULA:C23H22F3N5O2S

SMILES: CN1C=CN=C2N=C(C3CCC3)N[C@@]21c1ccc(S(=O)(=O)Nc2ccccc2C(F)(F)F)cc1

BIRTHDAY: 2018-11-19T08:15:41.548856
ATC: J01D
- ANTIINFECTIVES FOR SYSTEMIC USE
- ANTIBACTERIALS FOR SYSTEMIC USE
- OTHER BETA-LACTAM ANTIBACTERIALS
Synthesis Plan
FORMULA:C27H29F3N6

SMILES: CC(C)Cc1cccc(-c2c[nH]nc2Nc2c(Nc3ccccc3C(C)C)ncnc2C(F)(F)F)c1

BIRTHDAY: 2018-11-19T08:15:41.562629
ATC: D11A
- DERMATOLOGICALS
- OTHER DERMATOLOGICAL PREPARATIONS
- OTHER DERMATOLOGICAL PREPARATIONS
Synthesis Plan
FORMULA:C23H30ClN7O

SMILES: Cc1ccc(CNc2nc(Nc3cc(CC(C)C)n(CC(=O)N(C)C)n3)ncc2Cl)cc1

BIRTHDAY: 2018-11-19T08:15:41.572935
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C25H31N5O3S

SMILES: COc1ccc(Nc2cc(-c3cccc(C(C)C)c3)ncn2)cc1N1CCN(S(C)(=O)=O)CC1

BIRTHDAY: 2018-11-19T08:15:41.592989
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C21H24ClF3N6

SMILES: CC(C)Cc1cc(Nc2c(Cl)ncnc2Nc2ccccc2C(F)(F)F)n(C(C)C)n1

BIRTHDAY: 2018-11-19T08:15:41.605304
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C21H26N8

SMILES: CC(C)Cc1cnn(C(C)C)c1-c1cncnc1Nc1cccc2c1NCN=N2

BIRTHDAY: 2018-11-19T08:15:41.615499
ATC: J01A
- ANTIINFECTIVES FOR SYSTEMIC USE
- ANTIBACTERIALS FOR SYSTEMIC USE
- TETRACYCLINES
Synthesis Plan
FORMULA:C25H24N4O4

SMILES: CC(C)c1ccccc1NC(=O)c1ccccc1[C@@]1(N)N[C@]2(C(=O)O)C=CC=CC2=NC1=O

BIRTHDAY: 2018-11-19T08:15:41.625906
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C30H30N6O2

SMILES: Cc1cccc(N[C@@]23C=NC=CC2=NC(=O)[C@](N)(c2ccccc2C(=O)Nc2ccccc2C(C)C)N3)c1

BIRTHDAY: 2018-11-19T08:15:41.637826
ATC: C10A
- CARDIOVASCULAR SYSTEM
- LIPID MODIFYING AGENTS
- LIPID MODIFYING AGENTS, PLAIN
Synthesis Plan
FORMULA:C22H22FN5O2S

SMILES: CN1C=CN=C2N=C(C3CCC3)N[C@@]21c1ccc(S(=O)(=O)Nc2ccccc2F)cc1

BIRTHDAY: 2018-11-19T08:15:41.648975
ATC: A02B
- ALIMENTARY TRACT AND METABOLISM
- DRUGS FOR ACID RELATED DISORDERS
- DRUGS FOR PEPTIC ULCER AND GASTRO-OESOPHAGEAL REFLUX DISEASE (GORD)
Synthesis Plan
FORMULA:C27H32N6O3

SMILES: CCOc1c(OC)ccc(OC)c1Nc1cnc(Nc2n[nH]cc2-c2cccc(CC(C)C)c2)nc1

BIRTHDAY: 2018-11-19T08:15:41.660145
ATC: N05A
- NERVOUS SYSTEM
- PSYCHOLEPTICS
- ANTIPSYCHOTICS
Synthesis Plan
FORMULA:C25H26N8O2S

SMILES: COc1ccc(Nc2ncc3c(n2)CC=C2N=CS[C@]23N)c2c3cc(cc12)NCCNCC(=O)NC3

BIRTHDAY: 2018-11-19T08:15:41.672121
ATC: H01B
- SYSTEMIC HORMONAL PREPARATIONS, EXCL. SEX HORMONES AND INSULINS
- PITUITARY AND HYPOTHALAMIC HORMONES AND ANALOGUES
- POSTERIOR PITUITARY LOBE HORMONES
Synthesis Plan
FORMULA:C17H17N5O2S

SMILES: COc1cccc(OC)c1Nc1ncc2c(n1)-c1sc(N)nc1CC2

BIRTHDAY: 2018-11-19T08:15:41.681560
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C25H28N6O2

SMILES: COc1ccc(Nc2nc(-c3ccc(C(C)C)cc3)c3[nH]cnc3n2)cc1N1CCOCC1

BIRTHDAY: 2018-11-19T08:15:41.691892
ATC: L04A
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- IMMUNOSUPPRESSANTS
- IMMUNOSUPPRESSANTS
Synthesis Plan
FORMULA:C32H33FN6O2

SMILES: CC(C)NC1=CC=N[C@]2(c3cccc(F)c3)C(=O)N=C[C@@](N)(c3ccccc3C(=O)Nc3ccccc3C(C)C)N12

BIRTHDAY: 2018-11-19T08:15:41.705238
ATC: M09A
- MUSCULO-SKELETAL SYSTEM
- OTHER DRUGS FOR DISORDERS OF THE MUSCULO-SKELETAL SYSTEM
- OTHER DRUGS FOR DISORDERS OF THE MUSCULO-SKELETAL SYSTEM
Synthesis Plan
FORMULA:C29H31FN8O2

SMILES: COc1ccc(N2CCN(C)CC2)cc1Nc1ncc2c(n1)-c1c(nn(C)c1C(=O)Nc1ccccc1F)CC2

BIRTHDAY: 2018-11-19T08:15:41.718179
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C18H18ClF3N6

SMILES: CC(C)Cc1c[nH]nc1Nc1c(Cl)ncnc1Nc1ccccc1C(F)(F)F

BIRTHDAY: 2018-11-19T08:15:41.747536
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C26H31N5O3S2

SMILES: CN1CC=Nc2[nH]c(-c3ccc(S(=O)(=O)Nc4cccc5c4CCCSCCCCCO5)cc3)nc21

BIRTHDAY: 2018-11-19T08:15:41.758706
ATC: A10B
- ALIMENTARY TRACT AND METABOLISM
- DRUGS USED IN DIABETES
- BLOOD GLUCOSE LOWERING DRUGS, EXCL. INSULINS
Synthesis Plan
FORMULA:C21H26FN7O

SMILES: CC(C)(C)NC1=CN[C@H]2N=C(c3c(F)cccc3O[C@@]3(N)CC=CC=CN3)NC2=N1

BIRTHDAY: 2018-11-19T08:15:41.769000
ATC: N05B
- NERVOUS SYSTEM
- PSYCHOLEPTICS
- ANXIOLYTICS
Synthesis Plan
FORMULA:C20H21ClFN5O

SMILES: CN(C)C(C)(C)NC(=O)c1cccc2nc(Nc3c(F)cccc3Cl)ncc12

BIRTHDAY: 2018-11-19T08:15:41.778408
ATC: C09C
- CARDIOVASCULAR SYSTEM
- AGENTS ACTING ON THE RENIN-ANGIOTENSIN SYSTEM
- ANGIOTENSIN II ANTAGONISTS, PLAIN
Synthesis Plan
FORMULA:C25H26N4O3S

SMILES: CN1C=CN=C2N=C(C3CCC3)N[C@@]21c1ccc(OCc2ccc3c(c2)CS(=O)(=O)C3)cc1

BIRTHDAY: 2018-11-19T08:15:41.789731
ATC: L01A
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- ALKYLATING AGENTS
Synthesis Plan
FORMULA:C23H23FN4O

SMILES: N[C@H]1C=NC=C2NC(c3ccccc3OCc3ccccc3F)=C(C3CCC3)N21

BIRTHDAY: 2018-11-19T08:15:41.799198
ATC: G03B
- GENITO URINARY SYSTEM AND SEX HORMONES
- SEX HORMONES AND MODULATORS OF THE GENITAL SYSTEM
- ANDROGENS
Synthesis Plan
FORMULA:C24H22N2O4

SMILES: CC(C)c1cccc(NC(=O)c2ccccc2C(=O)Nc2ccc(C(=O)O)cc2)c1

BIRTHDAY: 2018-11-19T08:15:41.808508
ATC: S01X
- SENSORY ORGANS
- OPHTHALMOLOGICALS
- OTHER OPHTHALMOLOGICALS
Synthesis Plan
FORMULA:C26H23N3O4

SMILES: CC(C)c1ccc(NC(=O)c2ccc(Cn3c(=O)c(C(=O)O)nc4ccccc43)cc2)cc1

BIRTHDAY: 2018-11-19T08:15:41.818256
ATC: B01A
- BLOOD AND BLOOD FORMING ORGANS
- ANTITHROMBOTIC AGENTS
- ANTITHROMBOTIC AGENTS
Synthesis Plan
FORMULA:C25H22F3N7O2S

SMILES: C[C@@]12N=C(c3ccccc3S(=O)(=O)Nc3cccc(C(F)(F)F)c3)NC1=NC=CN2[C@@H](N)c1ccncc1

BIRTHDAY: 2018-11-19T08:15:41.831000
ATC: C04A
- CARDIOVASCULAR SYSTEM
- PERIPHERAL VASODILATORS
- PERIPHERAL VASODILATORS
Synthesis Plan
FORMULA:C24H28N8O3

SMILES: COc1ccc(N2CCN(C(C)=O)CC2)cc1Nc1ncc2c(n1)-c1c(c(C(N)=O)nn1C)CC2

BIRTHDAY: 2018-11-19T08:15:41.842766
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C20H18F3N5O2S

SMILES: CC1=NC2=NC=CN(C)[C@@]2(c2ccc(S(=O)(=O)Nc3cccc(C(F)(F)F)c3)cc2)N1

BIRTHDAY: 2018-11-19T08:15:41.854381
ATC: J01E
- ANTIINFECTIVES FOR SYSTEMIC USE
- ANTIBACTERIALS FOR SYSTEMIC USE
- SULFONAMIDES AND TRIMETHOPRIM
Synthesis Plan
FORMULA:C25H23FN6

SMILES: Cc1cccc(-c2ncc(C#N)c(Nc3cc(CC(C)C)n(-c4ccc(F)cc4)n3)n2)c1

BIRTHDAY: 2018-11-19T08:15:41.864473
ATC: N02A
- NERVOUS SYSTEM
- ANALGESICS
- OPIOIDS
Synthesis Plan
FORMULA:C20H24N4O2S

SMILES: Cc1c2ncnc1-c1cccc(c1)C(C)(C)NCCCNCC(=O)C(=O)S2

BIRTHDAY: 2018-11-19T08:15:41.873947
ATC: M03A
- MUSCULO-SKELETAL SYSTEM
- MUSCLE RELAXANTS
- MUSCLE RELAXANTS, PERIPHERALLY ACTING AGENTS
Synthesis Plan
FORMULA:C22H21FN4O

SMILES: CC(C)c1ccccc1Nc1ncc2c(n1)CC(=O)N(c1cccc(F)c1)C2

BIRTHDAY: 2018-11-19T08:15:41.882718
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C21H24ClF3N6

SMILES: CC(C)Cc1c(Nc2ncc(Cl)c(Nc3cccc(C(F)(F)F)c3)n2)cnn1C(C)C

BIRTHDAY: 2018-11-19T08:15:41.893722
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C24H33ClN6

SMILES: Cc1ccc(CNc2ncnc(Cl)c2Nc2nn(CC(C)C)cc2CC(C)(C)C)cc1

BIRTHDAY: 2018-11-19T08:15:41.903286
ATC: J05A
- ANTIINFECTIVES FOR SYSTEMIC USE
- ANTIVIRALS FOR SYSTEMIC USE
- DIRECT ACTING ANTIVIRALS
Synthesis Plan
FORMULA:C18H24N6

SMILES: CC1=NC(Nc2ccccc2C)=N[C@@]1(N)n1nccc1CC(C)C

BIRTHDAY: 2018-11-19T08:15:41.911922
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C23H23FN4O

SMILES: N[C@@]12C=NC=CN1C(C1CCC1)=C(c1ccccc1OCc1cccc(F)c1)N2

BIRTHDAY: 2018-11-19T08:15:41.921464
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C24H29N5O

SMILES: Cc1ccc(C)c(Nc2cnc(-c3ccccc3C(=O)N[C@H](C)N(C)C)nc2)c1C

BIRTHDAY: 2018-11-19T08:15:41.930736
ATC: C09C
- CARDIOVASCULAR SYSTEM
- AGENTS ACTING ON THE RENIN-ANGIOTENSIN SYSTEM
- ANGIOTENSIN II ANTAGONISTS, PLAIN
Synthesis Plan
FORMULA:C22H29N9O2

SMILES: CN(C)C(C)(C)NC(=O)c1ccc(Nc2ncc3c(n2)C[C@@]2(N)NN=C(C(N)=O)[C@H]2C3)cc1

BIRTHDAY: 2018-11-19T08:15:41.941798
ATC: M01C
- MUSCULO-SKELETAL SYSTEM
- ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS
- SPECIFIC ANTIRHEUMATIC AGENTS
Synthesis Plan
FORMULA:C23H20F3N5O2S

SMILES: Nc1nccn2c(-c3cccc(S(=O)(=O)Nc4ccccc4C(F)(F)F)c3)c(C3CCC3)nc12

BIRTHDAY: 2018-11-19T08:15:41.953581
ATC: A03F
- ALIMENTARY TRACT AND METABOLISM
- DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS
- PROPULSIVES
Synthesis Plan
FORMULA:C30H26N6O4

SMILES: CC(C)c1ccc(NC(=O)c2ccc(Cn3c(=O)c(C(=O)O)nc4cnc(Nc5ccccc5)nc43)cc2)cc1

BIRTHDAY: 2018-11-19T08:15:41.977430
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C24H28N8O3

SMILES: COc1ccc(N2CCN(C(C)=O)CC2)cc1Nc1ncc2c(n1)-c1c(nn(C)c1C(N)=O)CC2

BIRTHDAY: 2018-11-19T08:15:41.989301
ATC: V08D
- VARIOUS
- CONTRAST MEDIA
- ULTRASOUND CONTRAST MEDIA
Synthesis Plan
FORMULA:C32H33FN6O2

SMILES: CC(C)NC1=C[C@@]2(c3ccc(F)cc3)N(C=N1)C(=O)C=N[C@]2(N)c1ccccc1C(=O)Nc1ccccc1C(C)C

BIRTHDAY: 2018-11-19T08:15:42.002010
ATC: G03B
- GENITO URINARY SYSTEM AND SEX HORMONES
- SEX HORMONES AND MODULATORS OF THE GENITAL SYSTEM
- ANDROGENS
Synthesis Plan
FORMULA:C42H39BN6O2

SMILES: N#Cc1ccccc1Nc1cnc(-c2cccc3c2[OH+][BH2-]O[C@@H]3n2c3ccc2CCCCC=CCCCc2cccc(c2)C2=NC(=C3)C=C2)nc1

BIRTHDAY: 2018-11-19T08:15:42.025774
ATC: N05A
- NERVOUS SYSTEM
- PSYCHOLEPTICS
- ANTIPSYCHOTICS
Synthesis Plan
FORMULA:C21H26N10O2

SMILES: COc1cccc(Nc2ncnc3c2[C@]2(N)C(=CC3)NN=C2C(N)=O)c1N1CCNC[C@H]1N

BIRTHDAY: 2018-11-19T08:15:42.038538
ATC: D11A
- DERMATOLOGICALS
- OTHER DERMATOLOGICAL PREPARATIONS
- OTHER DERMATOLOGICAL PREPARATIONS
Synthesis Plan
FORMULA:C26H26N6

SMILES: Cc1cccc(-n2ncc(Nc3ncc4[nH]ccc4n3)c2-c2ccccc2CC(C)C)c1

BIRTHDAY: 2018-11-19T08:15:42.048283
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C24H24FN5O4

SMILES: COc1cc(OCC(=O)Nc2ccc(F)cc2)ccc1Nc1ncc2c(n1)OCCCC(N)=C2

BIRTHDAY: 2018-11-19T08:15:42.059166
ATC: M01A
- MUSCULO-SKELETAL SYSTEM
- ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS
- ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS
Synthesis Plan
FORMULA:C20H21F6N7

SMILES: CC(C)Cc1c(Nc2c(NCc3ccc(C(F)(F)F)cc3)ncnc2C(F)(F)F)n[nH]c1N

BIRTHDAY: 2018-11-19T08:15:42.072546
ATC: C02B
- CARDIOVASCULAR SYSTEM
- ANTIHYPERTENSIVES
- ANTIADRENERGIC AGENTS, GANGLION-BLOCKING
Synthesis Plan
FORMULA:C26H33N7

SMILES: CC(C)Cc1ccccc1-c1c2c(nn1C)[C@H]1C=NC=N[C@@]1(Nc1cnn(C(C)C)c1)CC2

BIRTHDAY: 2018-11-19T08:15:42.082580
ATC: B06A
- BLOOD AND BLOOD FORMING ORGANS
- OTHER HEMATOLOGICAL AGENTS
- OTHER HEMATOLOGICAL AGENTS
Synthesis Plan
FORMULA:C19H23ClN6

SMILES: Cc1ccccc1CNc1ncc(Cl)c(Nc2cc(CC(C)C)[nH]n2)n1

BIRTHDAY: 2018-11-19T08:15:42.091615
ATC: N06A
- NERVOUS SYSTEM
- PSYCHOANALEPTICS
- ANTIDEPRESSANTS
Synthesis Plan
FORMULA:C21H28N10O2

SMILES: COc1cccc(Nc2ncc3c(n2)C[C@@]2(N)NN=C(C(N)=O)[C@@H]2C3)c1N1CCNC[C@H]1N

BIRTHDAY: 2018-11-19T08:15:42.103194
ATC: B03B
- BLOOD AND BLOOD FORMING ORGANS
- ANTIANEMIC PREPARATIONS
- VITAMIN B12 AND FOLIC ACID
Synthesis Plan
FORMULA:C29H40N8O3

SMILES: CC(C)Cc1ccc(-c2cc(Nc3ccnc(N[C@H]4COCCCN(CCN5CCOCC5)C4=O)n3)n[nH]2)cc1

BIRTHDAY: 2018-11-19T08:15:42.115544
ATC: N05A
- NERVOUS SYSTEM
- PSYCHOLEPTICS
- ANTIPSYCHOTICS
Synthesis Plan
FORMULA:C23H22F2N4O

SMILES: CN1C=CN=C2NC(c3ccc(OCc4cccc(F)c4F)cc3)=N[C@]21C1CCC1

BIRTHDAY: 2018-11-19T08:15:42.125543
ATC: N06A
- NERVOUS SYSTEM
- PSYCHOANALEPTICS
- ANTIDEPRESSANTS
Synthesis Plan
FORMULA:C26H33N7

SMILES: CC(C)Cc1ccccc1-c1nn(C)c2c1CC[C@@]1(Nc3cnn(C(C)C)c3)N=CN=C[C@H]21

BIRTHDAY: 2018-11-19T08:15:42.135787
ATC: N02C
- NERVOUS SYSTEM
- ANALGESICS
- ANTIMIGRAINE PREPARATIONS
Synthesis Plan
FORMULA:C21H28N10O2

SMILES: COc1cccc(Nc2ncnc3c2[C@@H]2C(C(N)=O)=NN[C@@]2(N)CC3)c1N1CCNC[C@H]1N

BIRTHDAY: 2018-11-19T08:15:42.158069
ATC: C09C
- CARDIOVASCULAR SYSTEM
- AGENTS ACTING ON THE RENIN-ANGIOTENSIN SYSTEM
- ANGIOTENSIN II ANTAGONISTS, PLAIN
Synthesis Plan
FORMULA:C26H30N6O2

SMILES: COc1ccc(Nc2nc(-c3ccc(C(C)(C)C)cc3)c3[nH]cnc3n2)cc1N1CCOCC1

BIRTHDAY: 2018-11-19T08:15:42.168639
ATC: L04A
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- IMMUNOSUPPRESSANTS
- IMMUNOSUPPRESSANTS
Synthesis Plan
FORMULA:C28H34N4O

SMILES: CC(=O)Nc1c(-c2ncncc2Nc2ccccc2C(C)(C)C)cccc1[C@@H]1CCC1(C)C

BIRTHDAY: 2018-11-19T08:15:42.179589
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C22H30N4O2S

SMILES: Cc1ccc(-c2csc(NC(=O)CN3CCC(NC(=O)CC(C)C)CC3)n2)cc1

BIRTHDAY: 2018-11-19T08:15:42.188699
ATC: J01D
- ANTIINFECTIVES FOR SYSTEMIC USE
- ANTIBACTERIALS FOR SYSTEMIC USE
- OTHER BETA-LACTAM ANTIBACTERIALS
Synthesis Plan
FORMULA:C25H24N4O2

SMILES: Cc1nc2cccnc2n(Cc2ccc(C(=O)Nc3ccc(C(C)C)cc3)cc2)c1=O

BIRTHDAY: 2018-11-19T08:15:42.197907
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C22H29N9O

SMILES: Cc1ccc(Nc2cnc(-c3n[nH]c(N)c3C(=O)N[C@@]3(N)CCCCN3)nc2)c(C)c1C

BIRTHDAY: 2018-11-30T17:23:33.171977
ATC: M01A
- MUSCULO-SKELETAL SYSTEM
- ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS
- ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS
Synthesis Plan
FORMULA:C19H25Cl2N7

SMILES: CC(C)n1cnc2c(Nc3ccc(Cl)c(Cl)c3)nc(NCCCN(C)C)nc21

BIRTHDAY: 2018-11-30T17:23:33.181882
ATC: J01M
- ANTIINFECTIVES FOR SYSTEMIC USE
- ANTIBACTERIALS FOR SYSTEMIC USE
- QUINOLONE ANTIBACTERIALS
Synthesis Plan
FORMULA:C22H29N9O2

SMILES: CN(C)C(C)(C)NC(=O)c1ccc(Nc2ncc3c(n2)C[C@]2(N)NN=C(C(N)=O)[C@H]2C3)cc1

BIRTHDAY: 2018-11-30T17:23:33.192846
ATC: M01C
- MUSCULO-SKELETAL SYSTEM
- ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS
- SPECIFIC ANTIRHEUMATIC AGENTS
Synthesis Plan
FORMULA:C36H38N6O4

SMILES: COc1cccc(Nc2nc(-c3ccccc3C)nc3c2N(c2cccc(C(=O)NCC(=O)N4CC[C@](C)(O)C4)c2)CCC=C3)c1

BIRTHDAY: 2018-11-30T17:23:33.206193
ATC: C08D
- CARDIOVASCULAR SYSTEM
- CALCIUM CHANNEL BLOCKERS
- SELECTIVE CALCIUM CHANNEL BLOCKERS WITH DIRECT CARDIAC EFFECTS
Synthesis Plan
FORMULA:C19H23ClN6

SMILES: Cc1ccccc1CNc1ncc(Cl)c(Nc2cc(CC(C)C)n[nH]2)n1

BIRTHDAY: 2018-11-30T17:23:33.224849
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C19H21FN4O3

SMILES: CC(C)C[C@@H](Nc1ncc2c(n1)CN(c1cccc(F)c1)CC2=O)C(=O)O

BIRTHDAY: 2018-11-30T17:23:33.234104
ATC: C02B
- CARDIOVASCULAR SYSTEM
- ANTIHYPERTENSIVES
- ANTIADRENERGIC AGENTS, GANGLION-BLOCKING
Synthesis Plan
FORMULA:C32H31FN6O2

SMILES: CC(C)Nc1ncc2nc(-c3ccccc3F)c(=O)n(Cc3ccc(C(=O)Nc4ccc(C(C)C)cc4)cc3)c2n1

BIRTHDAY: 2018-11-30T17:23:33.245743
ATC: M01A
- MUSCULO-SKELETAL SYSTEM
- ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS
- ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS
Synthesis Plan
FORMULA:C25H30N6O

SMILES: CC(C)CC(=O)N[C@H]1CCCCN1c1ccccc1Nc1cncnc1-c1ccncc1

BIRTHDAY: 2018-11-30T17:23:33.255646
ATC: N05A
- NERVOUS SYSTEM
- PSYCHOLEPTICS
- ANTIPSYCHOTICS
Synthesis Plan
FORMULA:C21H26N10O2

SMILES: COc1cccc(Nc2ncnc3c2[C@@]2(N)C(=CC3)NN=C2C(N)=O)c1N1CCNC[C@H]1N

BIRTHDAY: 2018-11-30T17:23:33.268252
ATC: D11A
- DERMATOLOGICALS
- OTHER DERMATOLOGICAL PREPARATIONS
- OTHER DERMATOLOGICAL PREPARATIONS
Synthesis Plan
FORMULA:C25H28N6O2

SMILES: COc1c(Nc2nc(-c3ccc(C(C)C)cc3)nc3[nH]cnc23)cccc1N1CCOCC1

BIRTHDAY: 2018-11-30T17:23:33.288810
ATC: P01B
- ANTIPARASITIC PRODUCTS, INSECTICIDES AND REPELLENTS
- ANTIPROTOZOALS
- ANTIMALARIALS
Synthesis Plan
FORMULA:C18H23N5O

SMILES: CC(C)Cc1ccc(-c2cc(C(=O)NC3=NCCN3)nn2C)cc1

BIRTHDAY: 2018-11-30T17:23:33.318893
ATC: N04A
- NERVOUS SYSTEM
- ANTI-PARKINSON DRUGS
- ANTICHOLINERGIC AGENTS
Synthesis Plan
FORMULA:C34H31N7O2

SMILES: CC(C)c1cccc(NC(=O)c2cccc([C@]3(N)C(c4ccncc4)=NC(=O)[C@@]4(Nc5ccccc5)N=CC=CN43)c2)c1

BIRTHDAY: 2018-11-30T17:23:33.333587
ATC: C10A
- CARDIOVASCULAR SYSTEM
- LIPID MODIFYING AGENTS
- LIPID MODIFYING AGENTS, PLAIN
Synthesis Plan
FORMULA:C22H22N10O2S

SMILES: COc1ccc(N2CCNc3nsnc32)cc1Nc1ncc2c(n1)-c1c(c(C(N)=O)nn1C)CC2

BIRTHDAY: 2018-12-02T16:06:41.115180
ATC: V04C
- VARIOUS
- DIAGNOSTIC AGENTS
- OTHER DIAGNOSTIC AGENTS
Synthesis Plan
FORMULA:C26H30N6O2

SMILES: COc1c(Nc2nc(-c3ccccc3C(C)(C)C)nc3nc[nH]c23)cccc1N1CCOCC1

BIRTHDAY: 2018-12-02T16:06:41.136010
ATC: P01B
- ANTIPARASITIC PRODUCTS, INSECTICIDES AND REPELLENTS
- ANTIPROTOZOALS
- ANTIMALARIALS
Synthesis Plan
FORMULA:C21H25N7O2

SMILES: CN(C)CCCNC(=O)c1ccc2c(c1)-c1nc(-c3cnc(N)cn3)cn1CCO2

BIRTHDAY: 2018-12-02T16:06:41.157041
ATC: A07A
- ALIMENTARY TRACT AND METABOLISM
- ANTIDIARRHEALS, INTESTINAL ANTIINFLAMMATORY/ANTIINFECTIVE AGENTS
- INTESTINAL ANTIINFECTIVES
Synthesis Plan
FORMULA:C22H23N3O4

SMILES: CC(C)c1ccc(NC(=O)c2ccc(CN3CC(C(=O)O)=NCC3=O)cc2)cc1

BIRTHDAY: 2018-12-02T16:06:41.180784
ATC: D01A
- DERMATOLOGICALS
- ANTIFUNGALS FOR DERMATOLOGICAL USE
- ANTIFUNGALS FOR TOPICAL USE
Synthesis Plan
FORMULA:C30H28N6O4

SMILES: CC(C)c1ccccc1NC(=O)c1ccccc1[C@]1(N)C(=O)N=C[C@@]2(C(=O)O)C=CN=C(Nc3ccccc3)N21

BIRTHDAY: 2018-12-02T16:06:41.212633
ATC: D07A
- DERMATOLOGICALS
- CORTICOSTEROIDS, DERMATOLOGICAL PREPARATIONS
- CORTICOSTEROIDS, PLAIN
Synthesis Plan
FORMULA:C23H23FN4O

SMILES: N[C@]12C=NC=CN1C(c1ccccc1OCc1cccc(F)c1)=C(C1CCC1)N2

BIRTHDAY: 2018-12-02T16:06:41.238468
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C17H17N5O2S

SMILES: COc1cccc(Nc2ncnc3c2C=C[C@@H]2SC=N[C@]32N)c1OC

BIRTHDAY: 2018-12-02T16:06:41.250828
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C26H25FN4O2

SMILES: CC(C)c1cccc(NC(=O)c2cccc([C@]3(N)NC(=O)CN=C3c3cccc(F)c3)c2)c1

BIRTHDAY: 2018-12-02T16:06:41.264572
ATC: N05C
- NERVOUS SYSTEM
- PSYCHOLEPTICS
- HYPNOTICS AND SEDATIVES
Synthesis Plan
FORMULA:C19H25Cl2N7

SMILES: CC(C)n1cnc2nc(Nc3c(Cl)cccc3Cl)nc(NC(C)(C)N(C)C)c21

BIRTHDAY: 2018-12-02T16:06:41.278097
ATC: N06A
- NERVOUS SYSTEM
- PSYCHOANALEPTICS
- ANTIDEPRESSANTS
Synthesis Plan
FORMULA:C21H19F3N4O

SMILES: CC(=O)NCc1ccccc1-c1ncc(Nc2c(C)cccc2C(F)(F)F)cn1

BIRTHDAY: 2018-12-02T16:06:41.291052
ATC: P02D
- ANTIPARASITIC PRODUCTS, INSECTICIDES AND REPELLENTS
- ANTHELMINTICS
- ANTICESTODALS
Synthesis Plan
FORMULA:C20H25ClN6

SMILES: CC(C)Cc1cn[nH]c1Nc1c(Cl)ncnc1Nc1ccccc1C(C)C

BIRTHDAY: 2018-12-02T16:06:41.303475
ATC: C09C
- CARDIOVASCULAR SYSTEM
- AGENTS ACTING ON THE RENIN-ANGIOTENSIN SYSTEM
- ANGIOTENSIN II ANTAGONISTS, PLAIN
Synthesis Plan
FORMULA:C21H28N10O2

SMILES: COc1cccc(Nc2ncnc3c2C[C@H]2C(C(N)=O)=NN[C@@]2(N)C3)c1N1CCNC[C@H]1N

BIRTHDAY: 2018-12-02T16:06:41.319523
ATC: B06A
- BLOOD AND BLOOD FORMING ORGANS
- OTHER HEMATOLOGICAL AGENTS
- OTHER HEMATOLOGICAL AGENTS
Synthesis Plan
FORMULA:C15H18N8O

SMILES: CC(C)c1cc(Nc2nccc(-c3cnn(C)c3C(N)=O)n2)n[nH]1

BIRTHDAY: 2018-12-02T16:06:41.331848
ATC: C03A
- CARDIOVASCULAR SYSTEM
- DIURETICS
- LOW-CEILING DIURETICS, THIAZIDES
Synthesis Plan
FORMULA:C25H21FN6O2S

SMILES: Cc1nc2c(NCc3cccnc3)nccn2c1-c1ccc(S(=O)(=O)Nc2ccccc2F)cc1

BIRTHDAY: 2018-12-03T10:43:03.035315
ATC: J01G
- ANTIINFECTIVES FOR SYSTEMIC USE
- ANTIBACTERIALS FOR SYSTEMIC USE
- AMINOGLYCOSIDE ANTIBACTERIALS
Synthesis Plan
FORMULA:C27H25N5O

SMILES: C1=CCNCc2cc(cc(-c3ccccn3)c2)Nc2nccc(n2)-c2cccc(c2)OCC1

BIRTHDAY: 2018-12-03T10:43:03.054965
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C30H28N6O4

SMILES: CC(C)c1ccccc1NC(=O)c1ccccc1[C@]1(N)C(C(=O)O)=NC(=O)[C@]2(Nc3ccccc3)C=CN=CN21

BIRTHDAY: 2018-12-03T10:43:03.082626
ATC: S01X
- SENSORY ORGANS
- OPHTHALMOLOGICALS
- OTHER OPHTHALMOLOGICALS
Synthesis Plan
FORMULA:C26H21F3N6O2S

SMILES: Cc1nc2c(NCc3ccccn3)nccn2c1-c1ccc(S(=O)(=O)Nc2ccc(C(F)(F)F)cc2)cc1

BIRTHDAY: 2018-12-03T10:43:03.104320
ATC: A10B
- ALIMENTARY TRACT AND METABOLISM
- DRUGS USED IN DIABETES
- BLOOD GLUCOSE LOWERING DRUGS, EXCL. INSULINS
Synthesis Plan
FORMULA:C19H17F3N6O2

SMILES: COC1=CCNn2nc(-c3ncncc3Nc3c(OC)cccc3C(F)(F)F)cc21

BIRTHDAY: 2018-12-03T10:43:03.125426
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C27H32N6

SMILES: CN(C)Cc1ccc(Nc2nccc(-c3cc(-c4ccc(C(C)(C)C)cc4)nn3C)n2)cc1

BIRTHDAY: 2018-12-03T10:43:03.144305
ATC: L04A
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- IMMUNOSUPPRESSANTS
- IMMUNOSUPPRESSANTS
Synthesis Plan
FORMULA:C20H21ClFN5O

SMILES: CN(C)CCCNC(=O)c1ccc2ncnc(Nc3ccc(F)c(Cl)c3)c2c1

BIRTHDAY: 2018-12-03T10:43:03.153697
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C21H22N4O4

SMILES: CC(C)c1ccccc1NC(=O)c1ccccc1[C@]1(N)N=CC(=O)N[C@H]1C(=O)O

BIRTHDAY: 2018-12-03T10:43:03.173206
ATC: D11A
- DERMATOLOGICALS
- OTHER DERMATOLOGICAL PREPARATIONS
- OTHER DERMATOLOGICAL PREPARATIONS
Synthesis Plan
FORMULA:C17H19N5O2S

SMILES: COc1cccc(Nc2ncc3c(n2)C[C@@H]2SC=N[C@]2(N)C3)c1OC

BIRTHDAY: 2018-12-03T10:43:03.182417
ATC: M01A
- MUSCULO-SKELETAL SYSTEM
- ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS
- ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS
Synthesis Plan
FORMULA:C27H27ClN2O

SMILES: N[C@@]1(c2ccccc2)[C@@H]2CCC[C@@H]3[C@@]2(O)N[C@@H]1[C@@]3(c1ccccc1)c1cccc(Cl)c1

BIRTHDAY: 2018-12-03T10:43:03.201426
ATC: A02A
- ALIMENTARY TRACT AND METABOLISM
- DRUGS FOR ACID RELATED DISORDERS
- ANTACIDS
Synthesis Plan
FORMULA:C20H25N7O4

SMILES: CNC(=O)[C@]12C=NN[C@]1(N)Cc1ncnc(Nc3c(OC)ccc(OC)c3OC)c1C2

BIRTHDAY: 2018-12-03T19:11:27.904111
ATC: C03C
- CARDIOVASCULAR SYSTEM
- DIURETICS
- HIGH-CEILING DIURETICS
Synthesis Plan
FORMULA:C23H24N6O

SMILES: COc1ccc(Nc2ncnc3c2[C@@]2(N)NN=C[C@@]2(Cc2ccccc2)CC3)cc1

BIRTHDAY: 2018-12-03T19:11:27.914032
ATC: N05B
- NERVOUS SYSTEM
- PSYCHOLEPTICS
- ANXIOLYTICS
Synthesis Plan
FORMULA:C25H24N6

SMILES: Cc1cccc(-c2cc(Nc3cc(CC(C)C)n(-c4ccccc4)n3)nc(C#N)n2)c1

BIRTHDAY: 2018-12-03T19:11:27.965248
ATC: C05B
- CARDIOVASCULAR SYSTEM
- VASOPROTECTIVES
- ANTIVARICOSE THERAPY
Synthesis Plan
FORMULA:C26H27F3N6

SMILES: CC(C)c1ccc(Nc2cc(C(F)(F)F)nc(Nc3cc(-c4ccc(C(C)C)cc4)[nH]n3)n2)cc1

BIRTHDAY: 2018-12-03T19:11:27.985449
ATC: N05A
- NERVOUS SYSTEM
- PSYCHOLEPTICS
- ANTIPSYCHOTICS
Synthesis Plan
FORMULA:C29H27N7O4

SMILES: CC(C)c1ccccc1NC(=O)c1ccccc1[C@]1(N)N[C@@]2(C(=O)O)N=C(Nc3ccccc3)N=CC2=NC1=O

BIRTHDAY: 2018-12-03T19:11:27.998145
ATC: D11A
- DERMATOLOGICALS
- OTHER DERMATOLOGICAL PREPARATIONS
- OTHER DERMATOLOGICAL PREPARATIONS
Synthesis Plan
FORMULA:C21H28N10O2

SMILES: COc1cccc(Nc2ncnc3c2C[C@H]2C(C(N)=O)=NN[C@]2(N)C3)c1N1CCNC[C@@H]1N

BIRTHDAY: 2018-12-03T19:11:28.010056
ATC: B06A
- BLOOD AND BLOOD FORMING ORGANS
- OTHER HEMATOLOGICAL AGENTS
- OTHER HEMATOLOGICAL AGENTS
Synthesis Plan
FORMULA:C27H32N4O4

SMILES: COc1cc(Nc2nccc(-c3cc(NC(C)=O)cc(C4CC(C)(C)C4)c3)n2)cc(OC)c1OC

BIRTHDAY: 2018-12-03T19:11:28.042306
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C25H28N6O2

SMILES: C[C@H](CO)Nc1cnccc1-n1c(=O)ccc2ncnc(Nc3cccc(C(C)(C)C)c3)c21

BIRTHDAY: 2018-12-03T19:11:28.077432
ATC: N02A
- NERVOUS SYSTEM
- ANALGESICS
- OPIOIDS
Synthesis Plan
FORMULA:C19H16F4N6O

SMILES: CNc1cnc(C(F)(F)F)nc1Nc1ccncc1CNC(=O)c1cccc(F)c1

BIRTHDAY: 2018-12-01T22:30:33.062153
ATC: B05X
- BLOOD AND BLOOD FORMING ORGANS
- BLOOD SUBSTITUTES AND PERFUSION SOLUTIONS
- I.V. SOLUTION ADDITIVES
Synthesis Plan
FORMULA:C19H18FN5O2S

SMILES: CC1=NC2=NC=CN(C)[C@@]2(c2ccc(S(=O)(=O)Nc3ccccc3F)cc2)N1

BIRTHDAY: 2018-12-01T22:30:33.072839
ATC: A02B
- ALIMENTARY TRACT AND METABOLISM
- DRUGS FOR ACID RELATED DISORDERS
- DRUGS FOR PEPTIC ULCER AND GASTRO-OESOPHAGEAL REFLUX DISEASE (GORD)
Synthesis Plan
FORMULA:C21H26N10O2

SMILES: COc1cccc(N2CCNC[C@H]2N)c1Nc1ncnc2c1C=C1C(C(N)=O)=NN[C@@]1(N)C2

BIRTHDAY: 2018-12-01T22:30:33.085031
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C27H29F3N6

SMILES: CC(C)Cc1ccc(-c2cc(Nc3nc(Nc4cccc(C(C)C)c4)ncc3C(F)(F)F)n[nH]2)cc1

BIRTHDAY: 2018-12-01T22:30:33.118341
ATC: H01C
- SYSTEMIC HORMONAL PREPARATIONS, EXCL. SEX HORMONES AND INSULINS
- PITUITARY AND HYPOTHALAMIC HORMONES AND ANALOGUES
- HYPOTHALAMIC HORMONES
Synthesis Plan
FORMULA:C18H18ClF3N6

SMILES: CC(C)Cc1cn[nH]c1Nc1c(Cl)ncnc1Nc1ccccc1C(F)(F)F

BIRTHDAY: 2018-12-01T22:30:33.128656
ATC: L01B
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- ANTIMETABOLITES
Synthesis Plan
FORMULA:C26H26ClN3O2

SMILES: CC(C)c1c(NC(=O)c2ccccc2C2CCC2)cccc1C(=O)Nc1ccncc1Cl

BIRTHDAY: 2018-12-01T22:30:33.137978
ATC: S01J
- SENSORY ORGANS
- OPHTHALMOLOGICALS
- DIAGNOSTIC AGENTS
Synthesis Plan
FORMULA:C17H17N5O2S

SMILES: COc1cccc(Nc2ncnc3c2C=C2SC=N[C@]2(N)C3)c1OC

BIRTHDAY: 2018-12-01T22:30:33.147331
ATC: N05A
- NERVOUS SYSTEM
- PSYCHOLEPTICS
- ANTIPSYCHOTICS
Synthesis Plan
FORMULA:C23H28N6O2

SMILES: COc1cccc(Nc2ncnc3ccc(=O)n(C(C)(C)[C@H]4N[C@@H]5CCN[C@H]4C5)c23)c1

BIRTHDAY: 2018-12-01T22:30:33.157868
ATC: D11A
- DERMATOLOGICALS
- OTHER DERMATOLOGICAL PREPARATIONS
- OTHER DERMATOLOGICAL PREPARATIONS
Synthesis Plan
FORMULA:C23H20F3N5O2S

SMILES: Nc1nccn2c(C3CCC3)nc(-c3ccc(S(=O)(=O)Nc4ccccc4C(F)(F)F)cc3)c12

BIRTHDAY: 2018-12-01T22:30:33.169545
ATC: D06B
- DERMATOLOGICALS
- ANTIBIOTICS AND CHEMOTHERAPEUTICS FOR DERMATOLOGICAL USE
- CHEMOTHERAPEUTICS FOR TOPICAL USE
Synthesis Plan
FORMULA:C24H25F3N8O

SMILES: CN(C)C(C)(C)Nc1nc(Nc2ccccc2C(=O)Nc2ccccc2C(F)(F)F)c2nc[nH]c2n1

BIRTHDAY: 2018-12-01T22:30:33.182267
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C23H24N6O2S

SMILES: C[C@H](O)CCNc1cccc(-c2c[nH]c3ccc(-c4nnc(NC(=O)C5CC5)s4)cc23)n1

BIRTHDAY: 2018-12-01T22:30:33.192663
ATC: G02C
- GENITO URINARY SYSTEM AND SEX HORMONES
- OTHER GYNECOLOGICALS
- OTHER GYNECOLOGICALS
Synthesis Plan
FORMULA:C21H28N10O2

SMILES: COc1cccc(Nc2ncnc3c2[C@H]2C(N)=NN[C@@]2(C(N)=O)CC3)c1N1CCNC[C@@H]1N

BIRTHDAY: 2018-12-01T22:30:33.214116
ATC: R06A
- RESPIRATORY SYSTEM
- ANTIHISTAMINES FOR SYSTEMIC USE
- ANTIHISTAMINES FOR SYSTEMIC USE
Synthesis Plan
FORMULA:C32H33FN6O2

SMILES: CC(C)NC1=C[C@@]2(c3cccc(F)c3)N(C=N1)C(=O)C=N[C@]2(N)c1ccccc1C(=O)Nc1ccccc1C(C)C

BIRTHDAY: 2018-12-01T22:30:33.227100
ATC: G03B
- GENITO URINARY SYSTEM AND SEX HORMONES
- SEX HORMONES AND MODULATORS OF THE GENITAL SYSTEM
- ANDROGENS
Synthesis Plan