matter.farm

Computer-generated molecule database for public drug discovery. About this project.

These compounds may interact with:

Mitogen-activated protein kinase kinase kinase 8

Potentially involved in: lung cancer; cancer; carcinoma; crohn's disease; ameloblastoma; bronchioloalveolar adenocarcinoma; liver cirrhosis, experimental; lung neoplasms; myocardial ischemia; autosomal recessive predisposition; active crohn's disease; active ulcerative colitis; acute myeloid leukemia; adrenocortical carcinoma; astrocytoma, pilocytic; chronic rhinosinusitis; cystic fibrosis; gastric carcinoma; interstitial cystitis; interstitial lung disease

Disease data sourced from Pharos.

Unknown Action

FORMULA:C22H18N2O5

SMILES: COc1ccccc1C(=O)Nc1cccc(C(=O)Nc2ccc(C(=O)O)cc2)c1

BIRTHDAY: 2018-12-01T14:10:52.852365
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C22H29N5O2

SMILES: CN1N=N[C@@](C)(c2ccc(Nc3ccc(C(C)(C)C)cc3)c(C(=O)O)c2)C[C@H]1N

BIRTHDAY: 2018-12-01T14:10:52.861709
ATC: N05A
- NERVOUS SYSTEM
- PSYCHOLEPTICS
- ANTIPSYCHOTICS
Synthesis Plan
FORMULA:C19H19F2N5O

SMILES: CC(C)[C@H](Nc1cc(F)cc(F)c1)C(=O)N[C@@]1(C#N)NN=C2C=CC=C[C@H]21

BIRTHDAY: 2018-12-01T14:10:52.870981
ATC: J01D
- ANTIINFECTIVES FOR SYSTEMIC USE
- ANTIBACTERIALS FOR SYSTEMIC USE
- OTHER BETA-LACTAM ANTIBACTERIALS
Synthesis Plan
FORMULA:C18H18F3NO2

SMILES: CC(C)(C)c1cccc(Nc2ccc(C(F)(F)F)cc2C(=O)O)c1

BIRTHDAY: 2018-12-01T14:10:52.879302
ATC: M01A
- MUSCULO-SKELETAL SYSTEM
- ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS
- ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS
Synthesis Plan
FORMULA:C23H18F4N2O3

SMILES: O=C(Nc1ccccc1C(=O)NC[C@@H](O)C(F)(F)F)c1ccc(-c2ccccc2F)cc1

BIRTHDAY: 2018-12-01T14:10:52.889536
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C18H11ClF3N3O

SMILES: O=C(Nc1c(F)cccc1F)c1cccnc1Nc1cccc(Cl)c1F

BIRTHDAY: 2018-12-01T14:10:52.898862
ATC: D10A
- DERMATOLOGICALS
- ANTI-ACNE PREPARATIONS
- ANTI-ACNE PREPARATIONS FOR TOPICAL USE
Synthesis Plan
FORMULA:C18H14F6N2O3

SMILES: CN(C)C(=O)c1cc(C(F)(F)F)ccc1Nc1ccc(C(F)(F)F)cc1C(=O)O

BIRTHDAY: 2018-12-01T14:10:52.909258
ATC: M01A
- MUSCULO-SKELETAL SYSTEM
- ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS
- ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS
Synthesis Plan
FORMULA:C22H18N2O5

SMILES: COc1ccccc1C(=O)Nc1ccc(C(=O)Nc2ccc(C(=O)O)cc2)cc1

BIRTHDAY: 2018-12-01T14:10:52.918167
ATC: L04A
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- IMMUNOSUPPRESSANTS
- IMMUNOSUPPRESSANTS
Synthesis Plan
FORMULA:C23H20N2O5

SMILES: COc1cccc(-c2ccc(C(=O)Nc3ccccc3C(=O)NCC(=O)O)cc2)c1

BIRTHDAY: 2018-12-01T14:10:52.927647
ATC: C03B
- CARDIOVASCULAR SYSTEM
- DIURETICS
- LOW-CEILING DIURETICS, EXCL. THIAZIDES
Synthesis Plan
FORMULA:C25H21FN4O2

SMILES: C[C@@H](NC(=O)c1ccccc1NC(=O)c1ccccc1-c1cccc(F)c1)c1cn[nH]c1

BIRTHDAY: 2018-12-01T14:10:52.937576
ATC: C03B
- CARDIOVASCULAR SYSTEM
- DIURETICS
- LOW-CEILING DIURETICS, EXCL. THIAZIDES
Synthesis Plan
FORMULA:C28H30N4O5S

SMILES: COc1cccc(C(=O)Nc2cccc(C(=O)N3Sc4ncn(C(C)(C)C(=O)O)c4C(C)=C3C(C)C)c2)c1

BIRTHDAY: 2018-12-01T14:10:52.949049
ATC: J01F
- ANTIINFECTIVES FOR SYSTEMIC USE
- ANTIBACTERIALS FOR SYSTEMIC USE
- MACROLIDES, LINCOSAMIDES AND STREPTOGRAMINS
Synthesis Plan
FORMULA:C17H15F3N2O3

SMILES: CN(C)C(=O)c1ccc(C(F)(F)F)cc1Nc1ccccc1C(=O)O

BIRTHDAY: 2018-12-01T14:10:52.968904
ATC: M01A
- MUSCULO-SKELETAL SYSTEM
- ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS
- ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS
Synthesis Plan
FORMULA:C28H28F3N3O3

SMILES: CN(C)C(=O)c1c(Nc2cccc(C(=O)O)c2C(F)(F)F)cccc1[C@@]12C=C[C@H]3C[C@H]1C=CCCN2C3

BIRTHDAY: 2018-12-01T14:10:52.981786
ATC: M04A
- MUSCULO-SKELETAL SYSTEM
- ANTIGOUT PREPARATIONS
- ANTIGOUT PREPARATIONS
Synthesis Plan
FORMULA:C16H14F5N

SMILES: CC(C)[C@@H](Nc1ccc(F)cc1F)c1cc(F)c(F)cc1F

BIRTHDAY: 2018-12-25T02:02:55.942185
ATC: A10B
- ALIMENTARY TRACT AND METABOLISM
- DRUGS USED IN DIABETES
- BLOOD GLUCOSE LOWERING DRUGS, EXCL. INSULINS
Synthesis Plan
FORMULA:C21H19F4N5O

SMILES: CC(C)[C@H](Nc1cc(F)cc(F)c1)C(=O)N[C@H]1C=NN(c2cccc(F)c2F)[C@@H]1C#N

BIRTHDAY: 2018-12-25T02:02:55.952996
ATC: N05A
- NERVOUS SYSTEM
- PSYCHOLEPTICS
- ANTIPSYCHOTICS
Synthesis Plan
FORMULA:C23H18F4N2O3

SMILES: O=C(Nc1ccccc1C(=O)NC[C@H](O)C(F)(F)F)c1ccc(-c2ccccc2F)cc1

BIRTHDAY: 2018-12-25T02:02:55.963391
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C20H24N6O2

SMILES: CC(C)Cn1ccc(-c2c[nH]c3c(C#N)c(N[C@@H](C(=O)O)C(C)C)cnc23)n1

BIRTHDAY: 2018-12-25T02:02:55.972812
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C24H22FN3O

SMILES: CC(C)(C)c1cccc(Nc2ccccc2-c2nc(-c3ccc(F)cc3)[n-][o+]2)c1

BIRTHDAY: 2018-12-25T02:02:55.981653
ATC: C08D
- CARDIOVASCULAR SYSTEM
- CALCIUM CHANNEL BLOCKERS
- SELECTIVE CALCIUM CHANNEL BLOCKERS WITH DIRECT CARDIAC EFFECTS
Synthesis Plan
FORMULA:C22H15ClFN5

SMILES: N#Cc1cnc2ccc(NCc3cccnc3)cc2c1Nc1ccc(Cl)c(F)c1

BIRTHDAY: 2018-12-25T02:02:55.991233
ATC: B01A
- BLOOD AND BLOOD FORMING ORGANS
- ANTITHROMBOTIC AGENTS
- ANTITHROMBOTIC AGENTS
Synthesis Plan
FORMULA:C18H14F6N2O3

SMILES: CN(C)C(=O)c1cccc(Nc2cccc(C(=O)O)c2C(F)(F)F)c1C(F)(F)F

BIRTHDAY: 2018-12-25T02:02:56.001470
ATC: N02B
- NERVOUS SYSTEM
- ANALGESICS
- OTHER ANALGESICS AND ANTIPYRETICS
Synthesis Plan
FORMULA:C23H20N2O5

SMILES: COc1ccc(-c2ccccc2C(=O)Nc2cccc(C(=O)NCC(=O)O)c2)cc1

BIRTHDAY: 2018-12-25T02:02:56.010926
ATC: C10A
- CARDIOVASCULAR SYSTEM
- LIPID MODIFYING AGENTS
- LIPID MODIFYING AGENTS, PLAIN
Synthesis Plan
FORMULA:C18H18F3NO2

SMILES: CC(C)(C)c1ccccc1Nc1cccc(C(=O)O)c1C(F)(F)F

BIRTHDAY: 2018-12-25T02:02:56.019195
ATC: C02K
- CARDIOVASCULAR SYSTEM
- ANTIHYPERTENSIVES
- OTHER ANTIHYPERTENSIVES
Synthesis Plan
FORMULA:C17H13F5N2O3

SMILES: CN(C)C(=O)c1cc(F)cc(Nc2cccc(C(=O)O)c2C(F)(F)F)c1F

BIRTHDAY: 2018-12-25T02:02:56.028915
ATC: M01A
- MUSCULO-SKELETAL SYSTEM
- ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS
- ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS
Synthesis Plan
FORMULA:C23H18F4N2O3

SMILES: O=C(NC[C@H](O)C(F)(F)F)c1cccc(NC(=O)c2cccc(-c3ccc(F)cc3)c2)c1

BIRTHDAY: 2018-12-25T02:02:56.039122
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C24H21ClF3N3O3

SMILES: CC(C)(C)c1c(Nc2cccc(C(=O)O)c2C(F)(F)F)cccc1C(=O)Nc1cnccc1Cl

BIRTHDAY: 2018-12-25T02:02:56.049717
ATC: C03B
- CARDIOVASCULAR SYSTEM
- DIURETICS
- LOW-CEILING DIURETICS, EXCL. THIAZIDES
Synthesis Plan
FORMULA:C22H13F6N3O

SMILES: N#Cc1ccc(Nc2ccccc2C(=O)Nc2ccc(C(F)(F)F)cc2)cc1C(F)(F)F

BIRTHDAY: 2018-12-25T02:02:56.060172
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C17H15F3N2O3

SMILES: CN(C)C(=O)c1cccc(Nc2ccc(C(=O)O)cc2)c1C(F)(F)F

BIRTHDAY: 2018-12-25T02:02:56.069064
ATC: D01A
- DERMATOLOGICALS
- ANTIFUNGALS FOR DERMATOLOGICAL USE
- ANTIFUNGALS FOR TOPICAL USE
Synthesis Plan
FORMULA:C35H41N5

SMILES: CCCc1ccc2cc1-c1ccnc(n1)Nc1cccc(c1)CN(c1ccc(C(C)(C)C)cc1)CC=CCNC2

BIRTHDAY: 2018-12-25T02:02:56.079574
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C18H18F3NO2

SMILES: CC(C)(C)c1ccc(Nc2ccc(C(F)(F)F)c(C(=O)O)c2)cc1

BIRTHDAY: 2018-12-03T02:38:59.716898
ATC: G01A
- GENITO URINARY SYSTEM AND SEX HORMONES
- GYNECOLOGICAL ANTIINFECTIVES AND ANTISEPTICS
- ANTIINFECTIVES AND ANTISEPTICS, EXCL. COMBINATIONS WITH CORTICOSTEROIDS
Synthesis Plan
FORMULA:C22H13F6N3O

SMILES: N#Cc1ccc(C(F)(F)F)c(Nc2ccc(C(=O)Nc3ccccc3C(F)(F)F)cc2)c1

BIRTHDAY: 2018-12-03T02:38:59.727725
ATC: N06A
- NERVOUS SYSTEM
- PSYCHOANALEPTICS
- ANTIDEPRESSANTS
Synthesis Plan
FORMULA:C42H53FN4O4

SMILES: O=C(Nc1ccc([C@]2(CCCCCCNCc3ccccc3)COCCNCCOCCNCCO2)cc1)c1ccc(-c2ccc(F)cc2)cc1

BIRTHDAY: 2018-12-03T02:38:59.741561
ATC: N02B
- NERVOUS SYSTEM
- ANALGESICS
- OTHER ANALGESICS AND ANTIPYRETICS
Synthesis Plan
FORMULA:C24H24N2O5

SMILES: Cc1cccc(C(=O)O)c1Nc1cccc(C(C)(C)C)c1[C@@H]1CN=CC(=O)C(=O)C1=O

BIRTHDAY: 2018-12-03T02:38:59.751565
ATC: M01A
- MUSCULO-SKELETAL SYSTEM
- ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS
- ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS
Synthesis Plan
FORMULA:C16H20N4

SMILES: CN(Cc1ccncc1C#N)[C@]12C=CC[C@@H](CCC1)N2

BIRTHDAY: 2018-12-03T02:38:59.759071
ATC: A05B
- ALIMENTARY TRACT AND METABOLISM
- BILE AND LIVER THERAPY
- LIVER THERAPY, LIPOTROPICS
Synthesis Plan
FORMULA:C27H18F4N2O2

SMILES: O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)c1ccccc1-c1ccccc1F

BIRTHDAY: 2018-12-03T02:38:59.769707
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C27H18F4N2O2

SMILES: O=C(Nc1ccc(C(F)(F)F)cc1)c1ccccc1NC(=O)c1ccccc1-c1ccccc1F

BIRTHDAY: 2018-12-03T02:38:59.780244
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C21H18FN5O

SMILES: N#C[C@H]1CC=Cc2ncnc(N3C(=O)[C@H]4CC[C@@]3(c3cccc(F)c3)CN4)c21

BIRTHDAY: 2018-12-03T02:38:59.790307
ATC: J05A
- ANTIINFECTIVES FOR SYSTEMIC USE
- ANTIVIRALS FOR SYSTEMIC USE
- DIRECT ACTING ANTIVIRALS
Synthesis Plan
FORMULA:C23H19ClFN3O2

SMILES: COc1ccccc1-c1c(C(N)=O)ccc2c1CC(Nc1cccc(F)c1Cl)=NC2

BIRTHDAY: 2018-12-03T02:38:59.800047
ATC: J01F
- ANTIINFECTIVES FOR SYSTEMIC USE
- ANTIBACTERIALS FOR SYSTEMIC USE
- MACROLIDES, LINCOSAMIDES AND STREPTOGRAMINS
Synthesis Plan
FORMULA:C18H18F3NO2

SMILES: CC(C)(C)c1ccc(Nc2ccc(C(=O)O)cc2C(F)(F)F)cc1

BIRTHDAY: 2018-12-03T02:38:59.827902
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C21H27NO2

SMILES: Cc1c(Nc2cccc(C(C)C)c2C(C)(C)C)cccc1C(=O)O

BIRTHDAY: 2018-12-03T02:38:59.854856
ATC: C10A
- CARDIOVASCULAR SYSTEM
- LIPID MODIFYING AGENTS
- LIPID MODIFYING AGENTS, PLAIN
Synthesis Plan
FORMULA:C27H28N4O2

SMILES: CN(C)C(=O)c1cc(C(C)(C)C)ccc1-c1ccc(Nc2ccc(C#N)cc2)c(C(N)=O)c1

BIRTHDAY: 2018-12-03T02:38:59.874605
ATC: N02B
- NERVOUS SYSTEM
- ANALGESICS
- OTHER ANALGESICS AND ANTIPYRETICS
Synthesis Plan
FORMULA:C28H23FN2O3

SMILES: O=C(NC[C@@H](O)c1ccccc1)c1cccc(NC(=O)c2ccccc2-c2cccc(F)c2)c1

BIRTHDAY: 2018-11-30T03:40:56.969737
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C25H24N2O4

SMILES: CC(C)(C)c1ccccc1C(=O)Nc1ccc(C(=O)Nc2ccc(C(=O)O)cc2)cc1

BIRTHDAY: 2018-11-30T03:40:56.978882
ATC: N07C
- NERVOUS SYSTEM
- OTHER NERVOUS SYSTEM DRUGS
- ANTIVERTIGO PREPARATIONS
Synthesis Plan
FORMULA:C16H15F4N

SMILES: CC(C)[C@@H](Nc1cc(F)ccc1F)c1c(F)cccc1F

BIRTHDAY: 2018-11-30T03:40:56.986895
ATC: A03F
- ALIMENTARY TRACT AND METABOLISM
- DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS
- PROPULSIVES
Synthesis Plan
FORMULA:C17H19NO2

SMILES: CC(C)(C)c1cccc(Nc2cccc(C(=O)O)c2)c1

BIRTHDAY: 2018-11-30T03:40:57.001903
ATC: J04B
- ANTIINFECTIVES FOR SYSTEMIC USE
- ANTIMYCOBACTERIALS
- DRUGS FOR TREATMENT OF LEPRA
Synthesis Plan
FORMULA:C21H14F2N2

SMILES: Fc1ccc(-c2cccc(C3=NN=CCc4ccc(F)cc43)c2)cc1

BIRTHDAY: 2018-11-30T03:40:57.009843
ATC: N05A
- NERVOUS SYSTEM
- PSYCHOLEPTICS
- ANTIPSYCHOTICS
Synthesis Plan
FORMULA:C19H17F6NO2

SMILES: CC(C)(C)c1cccc(C(F)(F)F)c1Nc1c(C(=O)O)cccc1C(F)(F)F

BIRTHDAY: 2018-11-30T03:40:57.020645
ATC: D11A
- DERMATOLOGICALS
- OTHER DERMATOLOGICAL PREPARATIONS
- OTHER DERMATOLOGICAL PREPARATIONS
Synthesis Plan
FORMULA:C15H10F3NO4

SMILES: O=C(O)c1ccc(Nc2cccc(C(=O)O)c2C(F)(F)F)cc1

BIRTHDAY: 2018-11-30T03:40:57.029184
ATC: N03A
- NERVOUS SYSTEM
- ANTIEPILEPTICS
- ANTIEPILEPTICS
Synthesis Plan
FORMULA:C25H24F2N2O3

SMILES: C[C@@H](Oc1ccccc1-c1ccc(-c2cc(F)ccc2F)cc1C(N)=O)N1CCOCC1

BIRTHDAY: 2018-11-30T03:40:57.047425
ATC: M01A
- MUSCULO-SKELETAL SYSTEM
- ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS
- ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS
Synthesis Plan
FORMULA:C19H21NO4

SMILES: Cc1cc(Nc2cccc(C(C)(C)C)c2C(=O)O)ccc1C(=O)O

BIRTHDAY: 2018-11-30T03:40:57.055166
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C24H21ClF3N3O3

SMILES: CC(C)(C)c1ccc(Nc2ccc(C(=O)O)cc2C(F)(F)F)c(C(=O)Nc2ncccc2Cl)c1

BIRTHDAY: 2018-11-30T03:40:57.074348
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C24H20F4N2O

SMILES: O=C(Nc1cc(F)cc(F)c1)C1=C[C@@H]2C[C@]3(Nc4cc(F)cc(F)c4)CC[C@]2(C=C1)C3

BIRTHDAY: 2018-11-30T03:40:57.084133
ATC: A11H
- ALIMENTARY TRACT AND METABOLISM
- VITAMINS
- OTHER PLAIN VITAMIN PREPARATIONS
Synthesis Plan
FORMULA:C28H26N6O2

SMILES: CN(C)C(=O)c1ccc2c(c1)Oc1cc(ccn1)-c1ccnc(n1)Nc1cccc(c1)CNCC=C2

BIRTHDAY: 2018-11-30T03:40:57.095065
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C19H17F6NO2

SMILES: CC(C)(C)c1ccc(Nc2ccc(C(F)(F)F)cc2C(=O)O)cc1C(F)(F)F

BIRTHDAY: 2018-11-30T03:40:57.105328
ATC: M01A
- MUSCULO-SKELETAL SYSTEM
- ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS
- ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS
Synthesis Plan
FORMULA:C18H11ClF3N3O

SMILES: O=C(Nc1ccc(F)cc1F)c1cccnc1Nc1ccc(F)c(Cl)c1

BIRTHDAY: 2018-11-30T03:40:57.114445
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C20H20F3N5O4

SMILES: CN(C)C(=O)c1cc([C@H]2NCNC(=O)N2)ccc1Nc1cc(C(=O)O)cc(C(F)(F)F)c1

BIRTHDAY: 2018-11-19T08:17:04.577660
ATC: M01A
- MUSCULO-SKELETAL SYSTEM
- ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS
- ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS
Synthesis Plan
FORMULA:C23H18F4N2O3

SMILES: O=C(NC[C@@H](O)C(F)(F)F)c1cccc(NC(=O)c2ccccc2-c2ccc(F)cc2)c1

BIRTHDAY: 2018-11-19T08:17:04.588016
ATC: G01A
- GENITO URINARY SYSTEM AND SEX HORMONES
- GYNECOLOGICAL ANTIINFECTIVES AND ANTISEPTICS
- ANTIINFECTIVES AND ANTISEPTICS, EXCL. COMBINATIONS WITH CORTICOSTEROIDS
Synthesis Plan
FORMULA:C27H31N5O3S2

SMILES: COc1cccc(C(=O)Nc2ccccc2[C@H]2CNCc3nc(cs3)C3=N[C@H](CNCCOC2)CS3)c1

BIRTHDAY: 2018-11-19T08:17:04.599788
ATC: J01F
- ANTIINFECTIVES FOR SYSTEMIC USE
- ANTIBACTERIALS FOR SYSTEMIC USE
- MACROLIDES, LINCOSAMIDES AND STREPTOGRAMINS
Synthesis Plan
FORMULA:C26H24N4O3

SMILES: COc1cccc(-c2ccc(C(=O)Nc3ccc(C(=O)NCCc4ccn[nH]4)cc3)cc2)c1

BIRTHDAY: 2018-11-19T08:17:04.618452
ATC: G04C
- GENITO URINARY SYSTEM AND SEX HORMONES
- UROLOGICALS
- DRUGS USED IN BENIGN PROSTATIC HYPERTROPHY
Synthesis Plan
FORMULA:C24H18F3N3O3

SMILES: O=C(Cn1ccc(-c2cc3c(cc2F)[C@H]2CC[C@H]3NC2=O)cc1=O)Nc1c(F)cccc1F

BIRTHDAY: 2018-11-19T08:17:04.629315
ATC: J04A
- ANTIINFECTIVES FOR SYSTEMIC USE
- ANTIMYCOBACTERIALS
- DRUGS FOR TREATMENT OF TUBERCULOSIS
Synthesis Plan
FORMULA:C21H13F5N2O3

SMILES: CN(C(=O)c1cc(F)cc(Nc2cc(F)c(F)c(C(=O)O)c2)c1F)c1cccc(F)c1

BIRTHDAY: 2018-11-19T08:17:04.639972
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C25H21FN4O2

SMILES: C[C@@H](NC(=O)c1ccccc1NC(=O)c1ccccc1-c1cccc(F)c1)c1cc[nH]n1

BIRTHDAY: 2018-11-19T08:17:04.650029
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C19H17FN4O2

SMILES: CC(C)[C@@H](Nc1c(C#N)ncc2c(-c3cccc(F)c3)c[nH]c12)C(=O)O

BIRTHDAY: 2018-11-19T08:17:04.660177
ATC: N05A
- NERVOUS SYSTEM
- PSYCHOLEPTICS
- ANTIPSYCHOTICS
Synthesis Plan
FORMULA:C18H18F3NO2

SMILES: CC(C)(C)c1c(Nc2cccc(C(=O)O)c2)cccc1C(F)(F)F

BIRTHDAY: 2018-11-19T08:17:04.668762
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C27H24F5NO2

SMILES: COc1cc(-c2cc(C(N)=O)ccc2-c2ccc(F)c(F)c2)ccc1C1(C(F)(F)F)CCCCC1

BIRTHDAY: 2018-11-19T08:17:04.680343
ATC: N05A
- NERVOUS SYSTEM
- PSYCHOLEPTICS
- ANTIPSYCHOTICS
Synthesis Plan
FORMULA:C28H40N2O2

SMILES: CC(C)(C)c1ccccc1Nc1ccc([C@@]2(C)OCCCCOC[C@@H]3CCC[C@@H]2N3)cc1

BIRTHDAY: 2018-11-19T08:17:04.689278
ATC: N05A
- NERVOUS SYSTEM
- PSYCHOLEPTICS
- ANTIPSYCHOTICS
Synthesis Plan
FORMULA:C21H23N3O2

SMILES: CN(C)C(=O)c1ccccc1-c1c(C(N)=O)ccc2c1CC(C)(C)N=C2

BIRTHDAY: 2018-11-19T08:17:04.698694
ATC: R07A
- RESPIRATORY SYSTEM
- OTHER RESPIRATORY SYSTEM PRODUCTS
- OTHER RESPIRATORY SYSTEM PRODUCTS
Synthesis Plan
FORMULA:C22H21FN2O2

SMILES: CC(C)[C@H](Nc1c(C(=O)O)ccnc1-c1ccccc1F)c1ccccc1

BIRTHDAY: 2018-11-19T08:17:04.708161
ATC: C10A
- CARDIOVASCULAR SYSTEM
- LIPID MODIFYING AGENTS
- LIPID MODIFYING AGENTS, PLAIN
Synthesis Plan
FORMULA:C25H21FN4O2

SMILES: C[C@H](NC(=O)c1ccccc1NC(=O)c1ccccc1-c1cccc(F)c1)c1cc[nH]n1

BIRTHDAY: 2018-11-19T08:17:04.718259
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C20H26N4O3

SMILES: CC(C)(C)c1cccc2c1CC(=O)OCCNCNc1cncc(n1)OC2

BIRTHDAY: 2018-11-19T08:17:04.742602
ATC: G03B
- GENITO URINARY SYSTEM AND SEX HORMONES
- SEX HORMONES AND MODULATORS OF THE GENITAL SYSTEM
- ANDROGENS
Synthesis Plan
FORMULA:C22H21FN2O2

SMILES: CC(C)[C@H](Nc1cnc(C(=O)O)c(-c2ccccc2F)c1)c1ccccc1

BIRTHDAY: 2018-11-19T08:17:04.751371
ATC: J05A
- ANTIINFECTIVES FOR SYSTEMIC USE
- ANTIVIRALS FOR SYSTEMIC USE
- DIRECT ACTING ANTIVIRALS
Synthesis Plan
FORMULA:C18H14F6N2O3

SMILES: CN(C)C(=O)c1cccc(Nc2cc(C(=O)O)ccc2C(F)(F)F)c1C(F)(F)F

BIRTHDAY: 2018-11-19T08:17:04.761922
ATC: N02B
- NERVOUS SYSTEM
- ANALGESICS
- OTHER ANALGESICS AND ANTIPYRETICS
Synthesis Plan
FORMULA:C21H14F3N3O

SMILES: N#Cc1ccc(Nc2ccc(C(=O)Nc3ccccc3C(F)(F)F)cc2)cc1

BIRTHDAY: 2018-11-19T08:17:04.771214
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C29H29N3O2

SMILES: COc1ccc([C@@H]2C=CCNCCCNc3cc4ccccc4nc3-c3ccc(cc3)O2)cc1

BIRTHDAY: 2018-11-19T08:17:04.800096
ATC: J01F
- ANTIINFECTIVES FOR SYSTEMIC USE
- ANTIBACTERIALS FOR SYSTEMIC USE
- MACROLIDES, LINCOSAMIDES AND STREPTOGRAMINS
Synthesis Plan
FORMULA:C18H13F9N2O

SMILES: CN(C)C(=O)c1cccc(Nc2cc(C(F)(F)F)ccc2C(F)(F)F)c1C(F)(F)F

BIRTHDAY: 2018-11-19T08:17:04.811162
ATC: N02B
- NERVOUS SYSTEM
- ANALGESICS
- OTHER ANALGESICS AND ANTIPYRETICS
Synthesis Plan
FORMULA:C20H27N5O2

SMILES: CC(C)[C@@H](Nc1cnc2[nH]cc(-c3ccn(CC(C)(C)C)n3)c2c1)C(=O)O

BIRTHDAY: 2018-11-19T08:17:04.820516
ATC: N05A
- NERVOUS SYSTEM
- PSYCHOLEPTICS
- ANTIPSYCHOTICS
Synthesis Plan
FORMULA:C23H26N4O3

SMILES: CN(C)c1ccc(C(=O)Nc2ccc(-c3ccc(NC[C@@H](O)CO)nc3)cc2)cc1

BIRTHDAY: 2018-11-19T08:17:04.829624
ATC: P03B
- ANTIPARASITIC PRODUCTS, INSECTICIDES AND REPELLENTS
- ECTOPARASITICIDES, INCL. SCABICIDES, INSECTICIDES AND REPELLENTS
- INSECTICIDES AND REPELLENTS
Synthesis Plan
FORMULA:C22H19F2N3O2

SMILES: CN(C)C(=O)c1ccc(-c2ccc(Nc3c(F)cccc3F)c(C(N)=O)c2)cc1

BIRTHDAY: 2018-11-19T08:17:04.838803
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C19H19N3O2S

SMILES: CC(C)(C)c1ccccc1Nc1cc(C(=O)O)cc(-c2cnns2)c1

BIRTHDAY: 2018-11-19T08:17:04.847534
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C24H28F3NO3

SMILES: CC(C)(C)[C@]12OCC(=O)CNCCc3cccc(c3)OCC=C1C=CC=C2C(F)(F)F

BIRTHDAY: 2018-11-19T08:17:04.857729
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C22H13F6N3O

SMILES: N#Cc1cc(Nc2ccc(C(=O)Nc3ccccc3C(F)(F)F)cc2)cc(C(F)(F)F)c1

BIRTHDAY: 2018-11-19T08:17:04.868553
ATC: N02B
- NERVOUS SYSTEM
- ANALGESICS
- OTHER ANALGESICS AND ANTIPYRETICS
Synthesis Plan
FORMULA:C16H15F4N

SMILES: CC(C)[C@H](Nc1cc(F)ccc1F)c1c(F)cccc1F

BIRTHDAY: 2018-11-19T08:17:04.876523
ATC: A03F
- ALIMENTARY TRACT AND METABOLISM
- DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS
- PROPULSIVES
Synthesis Plan
FORMULA:C25H21FN2O3

SMILES: O=C(Nc1ccccc1C(=O)NC[C@@H]1CC=CO1)c1ccc(-c2ccccc2F)cc1

BIRTHDAY: 2018-11-19T08:17:04.885990
ATC: C10A
- CARDIOVASCULAR SYSTEM
- LIPID MODIFYING AGENTS
- LIPID MODIFYING AGENTS, PLAIN
Synthesis Plan
FORMULA:C23H18F4N2O3

SMILES: O=C(NC[C@@H](O)C(F)(F)F)c1cccc(NC(=O)c2cccc(-c3cccc(F)c3)c2)c1

BIRTHDAY: 2018-11-19T08:17:04.903316
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C23H18F4N2O3

SMILES: O=C(NC[C@@H](O)C(F)(F)F)c1cccc(NC(=O)c2ccccc2-c2cccc(F)c2)c1

BIRTHDAY: 2018-11-19T08:17:04.913628
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C19H21NO4

SMILES: Cc1ccc(Nc2ccc(C(C)(C)C)cc2C(=O)O)c(C(=O)O)c1

BIRTHDAY: 2018-11-19T08:17:04.921813
ATC: M01A
- MUSCULO-SKELETAL SYSTEM
- ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS
- ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS
Synthesis Plan
FORMULA:C25H21N3O3

SMILES: CN(C)C(=O)c1cccc(Nc2ccc(-c3ccc4ccccc4n3)cc2C(=O)O)c1

BIRTHDAY: 2018-11-19T08:17:04.931241
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C28H20F3N3O

SMILES: N#Cc1ccccc1-c1cccc(CNc2cccc(C(=O)Nc3cccc(C(F)(F)F)c3)c2)c1

BIRTHDAY: 2018-11-19T08:17:04.959237
ATC: R07A
- RESPIRATORY SYSTEM
- OTHER RESPIRATORY SYSTEM PRODUCTS
- OTHER RESPIRATORY SYSTEM PRODUCTS
Synthesis Plan
FORMULA:C25H21FN4O2

SMILES: O=C(NCCc1ccn[nH]1)c1cccc(NC(=O)c2ccc(-c3ccccc3F)cc2)c1

BIRTHDAY: 2018-11-19T08:17:04.968945
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C24H23N7O4

SMILES: CN(C)CC(=O)Nc1ccccc1-c1c(Nc2cccc3c2OCO3)cnc2c(=O)[nH]c(N)nc12

BIRTHDAY: 2018-11-19T08:17:04.980841
ATC: V04C
- VARIOUS
- DIAGNOSTIC AGENTS
- OTHER DIAGNOSTIC AGENTS
Synthesis Plan
FORMULA:C23H18F4N2O3

SMILES: O=C(NC[C@@H](O)C(F)(F)F)c1cccc(NC(=O)c2cccc(-c3ccc(F)cc3)c2)c1

BIRTHDAY: 2018-11-19T08:17:05.002284
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C24H32N2

SMILES: CC(C)(C)c1cccc(Nc2ccc([C@@]3(C)CCN4CC[C@@H]3C4)cc2)c1

BIRTHDAY: 2018-11-19T08:17:05.009669
ATC: S01F
- SENSORY ORGANS
- OPHTHALMOLOGICALS
- MYDRIATICS AND CYCLOPLEGICS
Synthesis Plan
FORMULA:C24H21FN4

SMILES: CC(C)[C@H](Nc1c(C#N)cnc2[nH]c(-c3ccc(F)cc3)cc12)c1ccccc1

BIRTHDAY: 2018-11-19T08:17:05.020032
ATC: N05A
- NERVOUS SYSTEM
- PSYCHOLEPTICS
- ANTIPSYCHOTICS
Synthesis Plan
FORMULA:C18H18F3NO2

SMILES: CC(C)(C)c1cccc(Nc2cc(C(F)(F)F)ccc2C(=O)O)c1

BIRTHDAY: 2018-11-19T08:17:05.038831
ATC: C02B
- CARDIOVASCULAR SYSTEM
- ANTIHYPERTENSIVES
- ANTIADRENERGIC AGENTS, GANGLION-BLOCKING
Synthesis Plan
FORMULA:C29H42FN5O2

SMILES: CC(C)(C)c1ccccc1Nc1cccc(C(=O)O)c1[C@@]1(F)CNC[C@H]2CC[C@@H](C2)NCCNCCN1

BIRTHDAY: 2018-11-19T08:17:05.050179
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C33H49N5O3S2

SMILES: CC(C)(C)c1ccc(Nc2ccc([C@@H]3C[C@H]4C=CCCSSC[C@@H](CNCCNCCO4)NCCN3)cc2C(=O)O)cc1

BIRTHDAY: 2018-11-19T08:17:05.062812
ATC: C02B
- CARDIOVASCULAR SYSTEM
- ANTIHYPERTENSIVES
- ANTIADRENERGIC AGENTS, GANGLION-BLOCKING
Synthesis Plan
FORMULA:C27H20N2O5

SMILES: O=C(O)c1ccc(NC(=O)c2ccc(NC(=O)c3ccccc3Oc3ccccc3)cc2)cc1

BIRTHDAY: 2018-11-19T08:17:05.072836
ATC: D11A
- DERMATOLOGICALS
- OTHER DERMATOLOGICAL PREPARATIONS
- OTHER DERMATOLOGICAL PREPARATIONS
Synthesis Plan
FORMULA:C18H25NO2

SMILES: C[C@@]12C=CC=C[C@@]1(C#N)CCCCCCCC(=O)COC2

BIRTHDAY: 2018-11-19T08:17:05.080088
ATC: G03B
- GENITO URINARY SYSTEM AND SEX HORMONES
- SEX HORMONES AND MODULATORS OF THE GENITAL SYSTEM
- ANDROGENS
Synthesis Plan
FORMULA:C23H18F4N2O3

SMILES: O=C(NC[C@H](O)C(F)(F)F)c1cccc(NC(=O)c2ccccc2-c2ccc(F)cc2)c1

BIRTHDAY: 2018-11-19T08:17:05.090368
ATC: G01A
- GENITO URINARY SYSTEM AND SEX HORMONES
- GYNECOLOGICAL ANTIINFECTIVES AND ANTISEPTICS
- ANTIINFECTIVES AND ANTISEPTICS, EXCL. COMBINATIONS WITH CORTICOSTEROIDS
Synthesis Plan
FORMULA:C27H20N2O5

SMILES: O=C(O)c1cccc(NC(=O)c2ccccc2NC(=O)c2ccc(Oc3ccccc3)cc2)c1

BIRTHDAY: 2018-11-19T08:17:05.100587
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C26H26N2O4S

SMILES: COc1ccc(C(=O)Nc2cccc(C(=O)Nc3cccc(C4(O)CCSCC4)c3)c2)cc1

BIRTHDAY: 2018-11-19T08:17:05.110398
ATC: D11A
- DERMATOLOGICALS
- OTHER DERMATOLOGICAL PREPARATIONS
- OTHER DERMATOLOGICAL PREPARATIONS
Synthesis Plan
FORMULA:C24H22Cl2N6O2

SMILES: CN(C)CC(=O)Nc1ccc(-c2cc3ncn(C)c(=O)c3c(Nc3ccc(Cl)cc3Cl)n2)cc1

BIRTHDAY: 2018-11-19T08:17:05.121513
ATC: H02A
- SYSTEMIC HORMONAL PREPARATIONS, EXCL. SEX HORMONES AND INSULINS
- CORTICOSTEROIDS FOR SYSTEMIC USE
- CORTICOSTEROIDS FOR SYSTEMIC USE, PLAIN
Synthesis Plan
FORMULA:C18H18F3NO2

SMILES: CC(C)(C)c1ccc(Nc2ccc(C(F)(F)F)cc2C(=O)O)cc1

BIRTHDAY: 2018-11-19T08:17:05.129655
ATC: M01A
- MUSCULO-SKELETAL SYSTEM
- ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS
- ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS
Synthesis Plan
FORMULA:C23H19F4N3O2

SMILES: O=C(Nc1ccccc1-c1ccncc1N1CCOCC1)c1cccc(F)c1C(F)(F)F

BIRTHDAY: 2018-11-19T08:17:05.140095
ATC: P01C
- ANTIPARASITIC PRODUCTS, INSECTICIDES AND REPELLENTS
- ANTIPROTOZOALS
- AGENTS AGAINST LEISHMANIASIS AND TRYPANOSOMIASIS
Synthesis Plan
FORMULA:C21H14F3N3O

SMILES: N#Cc1cccc(Nc2cccc(C(=O)Nc3ccc(C(F)(F)F)cc3)c2)c1

BIRTHDAY: 2018-11-19T08:17:05.149055
ATC: J01F
- ANTIINFECTIVES FOR SYSTEMIC USE
- ANTIBACTERIALS FOR SYSTEMIC USE
- MACROLIDES, LINCOSAMIDES AND STREPTOGRAMINS
Synthesis Plan
FORMULA:C18H14F6N2O3

SMILES: CN(C)C(=O)c1cc(Nc2ccc(C(=O)O)c(C(F)(F)F)c2)ccc1C(F)(F)F

BIRTHDAY: 2018-11-19T08:17:05.159275
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C18H18F3NO2

SMILES: CC(C)(C)c1ccccc1Nc1ccc(C(=O)O)c(C(F)(F)F)c1

BIRTHDAY: 2018-11-30T17:23:18.617378
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C28H27N3O2S

SMILES: CC(C)(C)c1ccc(Nc2ccc([C@H]3Nc4cc5ccccc5nc4CS3)cc2C(=O)O)cc1

BIRTHDAY: 2018-11-30T17:23:18.627696
ATC: R03D
- RESPIRATORY SYSTEM
- DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES
- OTHER SYSTEMIC DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES
Synthesis Plan
FORMULA:C27H16F2N6O2S

SMILES: NC(=O)c1cc(-c2ccc(Oc3cc4sc(-c5nnn[nH]5)cc4cn3)cc2)cc(-c2ccc(F)cc2F)c1

BIRTHDAY: 2018-11-30T17:23:18.639598
ATC: A10X
- ALIMENTARY TRACT AND METABOLISM
- DRUGS USED IN DIABETES
- OTHER DRUGS USED IN DIABETES
Synthesis Plan
FORMULA:C29H30N4O

SMILES: CC(C)(C)c1ccc(N2CCc3cccc(c3)OCc3cccc(c3)Nc3nccc2n3)cc1

BIRTHDAY: 2018-11-30T17:23:18.649109
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C18H18FNO3

SMILES: CC(C)(C)c1ccccc1C(=O)Nc1c(F)cccc1C(=O)O

BIRTHDAY: 2018-11-30T17:23:18.702012
ATC: P03B
- ANTIPARASITIC PRODUCTS, INSECTICIDES AND REPELLENTS
- ECTOPARASITICIDES, INCL. SCABICIDES, INSECTICIDES AND REPELLENTS
- INSECTICIDES AND REPELLENTS
Synthesis Plan
FORMULA:C25H21FN4O2

SMILES: C[C@@H](NC(=O)c1ccc(NC(=O)c2ccccc2-c2cccc(F)c2)cc1)c1ccn[nH]1

BIRTHDAY: 2018-11-30T17:23:18.711725
ATC: N02B
- NERVOUS SYSTEM
- ANALGESICS
- OTHER ANALGESICS AND ANTIPYRETICS
Synthesis Plan
FORMULA:C18H18F3NO2

SMILES: CC(C)(C)c1cccc(Nc2cccc(C(=O)O)c2C(F)(F)F)c1

BIRTHDAY: 2018-11-30T17:23:18.737396
ATC: C05A
- CARDIOVASCULAR SYSTEM
- VASOPROTECTIVES
- AGENTS FOR TREATMENT OF HEMORRHOIDS AND ANAL FISSURES FOR TOPICAL USE
Synthesis Plan
FORMULA:C23H19F4N3O2

SMILES: O=C(Nc1cccc(-c2cncc(N3CCOCC3)c2)c1)c1ccc(F)c(C(F)(F)F)c1

BIRTHDAY: 2018-11-30T17:23:18.747578
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C18H18F3NO2

SMILES: CC(C)(C)c1ccccc1Nc1cc(C(=O)O)cc(C(F)(F)F)c1

BIRTHDAY: 2018-11-30T17:23:18.755844
ATC: C02K
- CARDIOVASCULAR SYSTEM
- ANTIHYPERTENSIVES
- OTHER ANTIHYPERTENSIVES
Synthesis Plan
FORMULA:C21H14FNO5

SMILES: O=C(O)c1ccc(-c2ccccc2C(=O)Nc2cc(F)cc(C(=O)O)c2)cc1

BIRTHDAY: 2018-11-30T17:23:18.765319
ATC: V09C
- VARIOUS
- DIAGNOSTIC RADIOPHARMACEUTICALS
- RENAL SYSTEM
Synthesis Plan
FORMULA:C17H15F3N2O3

SMILES: CN(C)C(=O)c1ccc(C(F)(F)F)c(Nc2ccc(C(=O)O)cc2)c1

BIRTHDAY: 2018-12-02T16:06:26.827033
ATC: M01A
- MUSCULO-SKELETAL SYSTEM
- ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS
- ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS
Synthesis Plan
FORMULA:C24H22FNO3

SMILES: CC(C)(C)c1ccc(Nc2ccccc2C(=O)O)c(C(=O)c2ccc(F)cc2)c1

BIRTHDAY: 2018-12-02T16:06:26.836043
ATC: N05A
- NERVOUS SYSTEM
- PSYCHOLEPTICS
- ANTIPSYCHOTICS
Synthesis Plan
FORMULA:C21H16N2O2

SMILES: COc1ccc(-c2cc3c(cc2C(N)=O)ncc2ccccc23)cc1

BIRTHDAY: 2018-12-02T16:06:26.871167
ATC: C10A
- CARDIOVASCULAR SYSTEM
- LIPID MODIFYING AGENTS
- LIPID MODIFYING AGENTS, PLAIN
Synthesis Plan
FORMULA:C27H23FN4O2

SMILES: O=C(Nc1cc(-c2cccnc2)cc(-c2cccc(N3CCOCC3)n2)c1)c1ccc(F)cc1

BIRTHDAY: 2018-12-02T16:06:26.911018
ATC: C03X
- CARDIOVASCULAR SYSTEM
- DIURETICS
- OTHER DIURETICS
Synthesis Plan
FORMULA:C24H19F2NO4

SMILES: COc1ccc(C2(C(=O)O)CC2)cc1-c1ccc(C(N)=O)cc1-c1ccc(F)c(F)c1

BIRTHDAY: 2018-12-02T16:06:26.929863
ATC: C08D
- CARDIOVASCULAR SYSTEM
- CALCIUM CHANNEL BLOCKERS
- SELECTIVE CALCIUM CHANNEL BLOCKERS WITH DIRECT CARDIAC EFFECTS
Synthesis Plan
FORMULA:C27H27FN4O3

SMILES: C[C@]1([C@H](O)CNC(=O)c2ccccc2NC(=O)c2ccccc2-c2cccc(F)c2)CC[CH+][N-]N1

BIRTHDAY: 2018-12-02T16:06:26.941195
ATC: C05B
- CARDIOVASCULAR SYSTEM
- VASOPROTECTIVES
- ANTIVARICOSE THERAPY
Synthesis Plan
FORMULA:C27H18F4N2O2

SMILES: O=C(Nc1ccc(C(=O)Nc2ccccc2C(F)(F)F)cc1)c1cccc(-c2cccc(F)c2)c1

BIRTHDAY: 2018-12-02T16:06:26.951834
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C23H16F4N2O2

SMILES: O=C(Nc1ccccc1[C@H]1C=NO[C@@H]1C(F)(F)F)c1cccc(-c2cccc(F)c2)c1

BIRTHDAY: 2018-12-02T16:06:26.970010
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C18H21NO2

SMILES: Cc1c(Nc2ccccc2C(C)(C)C)cccc1C(=O)O

BIRTHDAY: 2018-12-03T10:42:48.517852
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C15H9F4NO4

SMILES: COC(=O)c1c(F)cc(F)cc1Nc1ccc(C(=O)O)c(F)c1F

BIRTHDAY: 2018-12-03T10:42:48.536237
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C25H24FN3O

SMILES: O=C(Nc1ccc([C@H]2N[C@H]3CNC[C@H]2C3)cc1)c1ccc(-c2ccc(F)cc2)cc1

BIRTHDAY: 2018-12-03T10:42:48.562663
ATC: C07A
- CARDIOVASCULAR SYSTEM
- BETA BLOCKING AGENTS
- BETA BLOCKING AGENTS
Synthesis Plan
FORMULA:C23H20N2O5

SMILES: COc1ccccc1-c1ccccc1C(=O)Nc1cccc(C(=O)NCC(=O)O)c1

BIRTHDAY: 2018-12-03T10:42:48.571979
ATC: V03A
- VARIOUS
- ALL OTHER THERAPEUTIC PRODUCTS
- ALL OTHER THERAPEUTIC PRODUCTS
Synthesis Plan
FORMULA:C28H32N2O2

SMILES: COc1ccc(-c2cccc(C(=O)N[C@H]3CCCCNCCc4cccc(c4)C3)c2)cc1

BIRTHDAY: 2018-12-03T10:42:48.590494
ATC: H01B
- SYSTEMIC HORMONAL PREPARATIONS, EXCL. SEX HORMONES AND INSULINS
- PITUITARY AND HYPOTHALAMIC HORMONES AND ANALOGUES
- POSTERIOR PITUITARY LOBE HORMONES
Synthesis Plan
FORMULA:C21H15FN2O4

SMILES: O=C(O)c1ccc(NC(=O)c2ccc(NC(=O)c3cccc(F)c3)cc2)cc1

BIRTHDAY: 2018-12-03T10:42:48.599365
ATC: C10A
- CARDIOVASCULAR SYSTEM
- LIPID MODIFYING AGENTS
- LIPID MODIFYING AGENTS, PLAIN
Synthesis Plan
FORMULA:C17H15F3N2O3

SMILES: CN(C)C(=O)c1ccc(C(F)(F)F)c(Nc2cccc(C(=O)O)c2)c1

BIRTHDAY: 2018-12-03T10:42:48.616581
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C21H14FNO5

SMILES: O=C(O)c1ccc(-c2ccccc2C(=O)Nc2c(F)cccc2C(=O)O)cc1

BIRTHDAY: 2018-12-03T10:42:48.680311
ATC: G01A
- GENITO URINARY SYSTEM AND SEX HORMONES
- GYNECOLOGICAL ANTIINFECTIVES AND ANTISEPTICS
- ANTIINFECTIVES AND ANTISEPTICS, EXCL. COMBINATIONS WITH CORTICOSTEROIDS
Synthesis Plan
FORMULA:C25H21FN4O2

SMILES: O=C(NCCc1ccn[nH]1)c1ccc(NC(=O)c2ccc(-c3ccccc3F)cc2)cc1

BIRTHDAY: 2018-12-03T19:11:13.664952
ATC: G04C
- GENITO URINARY SYSTEM AND SEX HORMONES
- UROLOGICALS
- DRUGS USED IN BENIGN PROSTATIC HYPERTROPHY
Synthesis Plan
FORMULA:C28H22FN5O

SMILES: N#Cc1c(Nc2cc(F)cc3c2CCC=C3)cncc1C(=O)Nc1cccc2c1[C@@H]1C=CC[C@@H]2N1

BIRTHDAY: 2018-12-03T19:11:13.675488
ATC: S01E
- SENSORY ORGANS
- OPHTHALMOLOGICALS
- ANTIGLAUCOMA PREPARATIONS AND MIOTICS
Synthesis Plan
FORMULA:C17H15F6N

SMILES: CC(C)(C)[C@H](Nc1ccc(F)cc1F)c1cc(F)c(F)c(F)c1F

BIRTHDAY: 2018-12-03T19:11:13.684166
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C16H11N5O3S

SMILES: CN(C(=O)C=O)c1ccccc1Nc1nc2scc(C#N)c2c(=O)[nH]1

BIRTHDAY: 2018-12-03T19:11:13.693460
ATC: D11A
- DERMATOLOGICALS
- OTHER DERMATOLOGICAL PREPARATIONS
- OTHER DERMATOLOGICAL PREPARATIONS
Synthesis Plan
FORMULA:C18H18F3NO2

SMILES: CC(C)(C)c1cccc(Nc2ccc(C(=O)O)cc2C(F)(F)F)c1

BIRTHDAY: 2018-12-03T19:11:13.712528
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C38H40F3N7O4

SMILES: CN(C)C(=O)c1cc(-c2c3cccc2Nc2nccc(n2)N2CCC[C@H](COCC=CCNC3)C2)ccc1Nc1ccc(C(F)(F)F)c(C(=O)O)c1

BIRTHDAY: 2018-12-03T19:11:13.728273
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C33H31FN2O3

SMILES: C[C@H]1Cc2cccc(c2)OCC=CCOc2cccc(c2-c2ccccc2NC(=O)c2ccc(F)cc2)CN1

BIRTHDAY: 2018-12-03T19:11:13.768309
ATC: N05A
- NERVOUS SYSTEM
- PSYCHOLEPTICS
- ANTIPSYCHOTICS
Synthesis Plan
FORMULA:C21H17BrN2O3

SMILES: O=C(NBr)c1cccc(NC(=O)c2ccc(OCc3ccccc3)cc2)c1

BIRTHDAY: 2018-12-03T19:11:13.776663
ATC: D10A
- DERMATOLOGICALS
- ANTI-ACNE PREPARATIONS
- ANTI-ACNE PREPARATIONS FOR TOPICAL USE
Synthesis Plan
FORMULA:C25H24FN3O3

SMILES: O=C(Nc1ccc(C(=O)N[C@H]2CNCCOC2)cc1)c1ccc(-c2ccccc2F)cc1

BIRTHDAY: 2018-12-03T19:11:13.786097
ATC: N02B
- NERVOUS SYSTEM
- ANALGESICS
- OTHER ANALGESICS AND ANTIPYRETICS
Synthesis Plan
FORMULA:C18H18F3NO2

SMILES: CC(C)(C)c1ccc(Nc2ccccc2C(=O)O)cc1C(F)(F)F

BIRTHDAY: 2018-12-01T22:30:18.640814
ATC: M01A
- MUSCULO-SKELETAL SYSTEM
- ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS
- ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS
Synthesis Plan
FORMULA:C19H20F3N5O3S

SMILES: CN(C)C(=O)c1c(Nc2cccc(C(=O)O)c2C(F)(F)F)cccc1[C@@H]1NS[C@H](N)N1

BIRTHDAY: 2018-12-01T22:30:18.661323
ATC: C08C
- CARDIOVASCULAR SYSTEM
- CALCIUM CHANNEL BLOCKERS
- SELECTIVE CALCIUM CHANNEL BLOCKERS WITH MAINLY VASCULAR EFFECTS
Synthesis Plan
FORMULA:C21H27NO2

SMILES: Cc1ccc(Nc2ccc(C(C)(C)C)cc2C(C)C)c(C(=O)O)c1

BIRTHDAY: 2018-12-01T22:30:18.668787
ATC: C02A
- CARDIOVASCULAR SYSTEM
- ANTIHYPERTENSIVES
- ANTIADRENERGIC AGENTS, CENTRALLY ACTING
Synthesis Plan
FORMULA:C24H24N2O2S2

SMILES: COc1ccc(C(=O)Nc2ccc([C@@]3(NCc4ccccc4)CCSS3)cc2)cc1

BIRTHDAY: 2018-12-01T22:30:18.688887
ATC: B01A
- BLOOD AND BLOOD FORMING ORGANS
- ANTITHROMBOTIC AGENTS
- ANTITHROMBOTIC AGENTS
Synthesis Plan
FORMULA:C35H32N6O2S

SMILES: CN(C)C(=O)c1cc(C#N)ccc1Nc1ccc(-c2ccc3c4c2C2=Nc5c(cccc5OCCCCN(C3)S4)NC2)cc1

BIRTHDAY: 2018-12-01T22:30:18.712572
ATC: A02B
- ALIMENTARY TRACT AND METABOLISM
- DRUGS FOR ACID RELATED DISORDERS
- DRUGS FOR PEPTIC ULCER AND GASTRO-OESOPHAGEAL REFLUX DISEASE (GORD)
Synthesis Plan
FORMULA:C23H20N2O5

SMILES: COc1cccc(-c2ccc(C(=O)Nc3ccc(C(=O)NCC(=O)O)cc3)cc2)c1

BIRTHDAY: 2018-12-01T22:30:18.747171
ATC: J01M
- ANTIINFECTIVES FOR SYSTEMIC USE
- ANTIBACTERIALS FOR SYSTEMIC USE
- QUINOLONE ANTIBACTERIALS
Synthesis Plan
FORMULA:C22H13F4NO

SMILES: Fc1ccc(-c2ccc(-c3cc(-c4ccc(C(F)(F)F)cc4)[n-][o+]3)cc2)cc1

BIRTHDAY: 2018-12-01T22:30:18.765715
ATC: A10B
- ALIMENTARY TRACT AND METABOLISM
- DRUGS USED IN DIABETES
- BLOOD GLUCOSE LOWERING DRUGS, EXCL. INSULINS
Synthesis Plan
FORMULA:C27H27FN2O3

SMILES: O=C(Nc1ccccc1C(=O)NCC1(O)CCCCC1)c1ccc(-c2ccccc2F)cc1

BIRTHDAY: 2018-12-01T22:30:18.783969
ATC: N01B
- NERVOUS SYSTEM
- ANESTHETICS
- ANESTHETICS, LOCAL
Synthesis Plan