matter.farm

Computer-generated molecule database for public drug discovery. About this project.

These compounds may interact with:

Beta-secretase 1

Potentially involved in: cardiovascular system disease; carcinoma; alzheimer's disease; dementia; amyloidosis; toxic encephalopathy; autosomal recessive nonsyndromic deafness 74; achromatopsia; down syndrome; cancer; schizophrenia; active crohn's disease; atypical teratoid / rhabdoid tumor; ependymoma; interstitial lung disease; intraductal papillary-mucinous adenoma (ipma); intraductal papillary-mucinous carcinoma (ipmc); intraductal papillary-mucinous neoplasm (ipmn); lung cancer; malignant mesothelioma

Disease data sourced from Pharos.

Inhibitor

FORMULA:C25H22FNO

SMILES: COc1ccc(-c2ccccc2[C@@]2(c3ccc(F)cc3)C3[C@@H]4CN2C[C@@H]34)cc1

BIRTHDAY: 2018-12-01T14:10:58.894366
ATC: A08A
- ALIMENTARY TRACT AND METABOLISM
- ANTIOBESITY PREPARATIONS, EXCL. DIET PRODUCTS
- ANTIOBESITY PREPARATIONS, EXCL. DIET PRODUCTS
Synthesis Plan
FORMULA:C25H24FNO2

SMILES: COc1ccccc1-c1cccc([C@]2(c3ccc(F)cc3)C[C@@H]3C[C@@H]2[C@H](N)O3)c1

BIRTHDAY: 2018-12-01T14:10:58.903309
ATC: N05A
- NERVOUS SYSTEM
- PSYCHOLEPTICS
- ANTIPSYCHOTICS
Synthesis Plan
FORMULA:C16H13FN4O3

SMILES: FC[C@@]12CN=CO[C@@]1(n1ccnc1-c1ccnc3c1OC=CO3)C2

BIRTHDAY: 2018-12-01T14:10:58.912842
ATC: J05A
- ANTIINFECTIVES FOR SYSTEMIC USE
- ANTIVIRALS FOR SYSTEMIC USE
- DIRECT ACTING ANTIVIRALS
Synthesis Plan
FORMULA:C24H28F2N4O

SMILES: FCC1=NC[C@H](n2ccc(C3(c4cccc(F)c4)C[C@@H]4CNC[C@H](C4)C3)n2)C2(CC2)O1

BIRTHDAY: 2018-12-01T14:10:58.922682
ATC: N02B
- NERVOUS SYSTEM
- ANALGESICS
- OTHER ANALGESICS AND ANTIPYRETICS
Synthesis Plan
FORMULA:C16H13F5N2O2

SMILES: O=C(Nc1c(F)cccc1CC(F)F)c1cnccc1OCC(F)F

BIRTHDAY: 2018-12-01T14:10:58.931889
ATC: V08A
- VARIOUS
- CONTRAST MEDIA
- X-RAY CONTRAST MEDIA, IODINATED
Synthesis Plan
FORMULA:C29H31F2N3O3

SMILES: COc1ccc([C@]2(c3ccc(F)cc3)CN(CCCCCC(=O)NCc3ccc(F)cc3)C(=O)N2)cc1

BIRTHDAY: 2018-12-01T14:10:58.942412
ATC: N03A
- NERVOUS SYSTEM
- ANTIEPILEPTICS
- ANTIEPILEPTICS
Synthesis Plan
FORMULA:C25H25ClFN5O

SMILES: C[C@@]1(c2cc(F)ccc2NC(=O)c2ccc(Cl)nc2)C[C@H]2CC[C@@H](CN2c2ccccn2)N1

BIRTHDAY: 2018-12-01T14:10:58.953249
ATC: N05A
- NERVOUS SYSTEM
- PSYCHOLEPTICS
- ANTIPSYCHOTICS
Synthesis Plan
FORMULA:C14H12F2N4O

SMILES: FCC1=NC[C@]2(n3ccnc3-c3ccncc3F)C[C@H]2O1

BIRTHDAY: 2018-12-01T14:10:58.961792
ATC: B03B
- BLOOD AND BLOOD FORMING ORGANS
- ANTIANEMIC PREPARATIONS
- VITAMIN B12 AND FOLIC ACID
Synthesis Plan
FORMULA:C15H14F2N4O

SMILES: FC[C@H]1COC(n2cnc(-c3ccnc(F)c3)c2)=NC12CC2

BIRTHDAY: 2018-12-01T14:10:58.970184
ATC: M09A
- MUSCULO-SKELETAL SYSTEM
- OTHER DRUGS FOR DISORDERS OF THE MUSCULO-SKELETAL SYSTEM
- OTHER DRUGS FOR DISORDERS OF THE MUSCULO-SKELETAL SYSTEM
Synthesis Plan
FORMULA:C15H14F2N4O

SMILES: FC[C@@H]1COC(n2cnc(-c3cccnc3F)c2)=NC12CC2

BIRTHDAY: 2018-12-01T14:10:58.978576
ATC: C01B
- CARDIOVASCULAR SYSTEM
- CARDIAC THERAPY
- ANTIARRHYTHMICS, CLASS I AND III
Synthesis Plan
FORMULA:C14H12F2N4O

SMILES: FCC1=NC[C@@]2(n3ccnc3-c3ccncc3F)C[C@@H]2O1

BIRTHDAY: 2018-12-01T14:10:58.987209
ATC: B03B
- BLOOD AND BLOOD FORMING ORGANS
- ANTIANEMIC PREPARATIONS
- VITAMIN B12 AND FOLIC ACID
Synthesis Plan
FORMULA:C26H27F2N3O6

SMILES: COc1cccc(C(=O)Nc2ccc(F)c([C@]3(CF)C[C@H]4[C@@H]5CC[C@]6(OC(=O)O3)[C@@H]4[C@@H](CN6C)O5)c2)n1

BIRTHDAY: 2018-12-01T14:10:58.999445
ATC: V08C
- VARIOUS
- CONTRAST MEDIA
- MAGNETIC RESONANCE IMAGING CONTRAST MEDIA
Synthesis Plan
FORMULA:C14H12F2N4O

SMILES: FCC1=NC[C@@]2(n3ccnc3-c3ccncc3F)C[C@H]2O1

BIRTHDAY: 2018-12-01T14:10:59.008028
ATC: B03B
- BLOOD AND BLOOD FORMING ORGANS
- ANTIANEMIC PREPARATIONS
- VITAMIN B12 AND FOLIC ACID
Synthesis Plan
FORMULA:C18H14ClFN2O3

SMILES: C[C@@]1(c2c(F)cccc2NC(=O)c2cnccc2Cl)OOC23CC21C3

BIRTHDAY: 2018-12-01T14:10:59.017181
ATC: C08C
- CARDIOVASCULAR SYSTEM
- CALCIUM CHANNEL BLOCKERS
- SELECTIVE CALCIUM CHANNEL BLOCKERS WITH MAINLY VASCULAR EFFECTS
Synthesis Plan
FORMULA:C14H11ClF2N2O

SMILES: O=C(Nc1ccc(F)c(CCF)c1)c1cccnc1Cl

BIRTHDAY: 2018-12-01T14:10:59.024962
ATC: C03X
- CARDIOVASCULAR SYSTEM
- DIURETICS
- OTHER DIURETICS
Synthesis Plan
FORMULA:C29H33ClF2N6O

SMILES: CC(C)[C@]1(N)C[C@H]2NC[C@H](N[C@]2(C)c2c(F)cccc2NC(=O)c2cnccc2Cl)[C@]1(N)c1cccc(F)c1

BIRTHDAY: 2018-12-01T14:10:59.037439
ATC: B03X
- BLOOD AND BLOOD FORMING ORGANS
- ANTIANEMIC PREPARATIONS
- OTHER ANTIANEMIC PREPARATIONS
Synthesis Plan
FORMULA:C22H24ClFN2O

SMILES: CC(C)C12CC(C1)C[C@@]2(C)c1c(F)cccc1NC(=O)c1ccnc(Cl)c1

BIRTHDAY: 2018-12-01T14:10:59.046988
ATC: C10A
- CARDIOVASCULAR SYSTEM
- LIPID MODIFYING AGENTS
- LIPID MODIFYING AGENTS, PLAIN
Synthesis Plan
FORMULA:C17H14F3N5O

SMILES: Fc1ncccc1C1=Cc2c(ncn2[C@@]23CN=CO[C@@]2(C(F)F)C3)CN1

BIRTHDAY: 2018-12-01T14:10:59.057394
ATC: D01A
- DERMATOLOGICALS
- ANTIFUNGALS FOR DERMATOLOGICAL USE
- ANTIFUNGALS FOR TOPICAL USE
Synthesis Plan
FORMULA:C20H16ClFN4O3

SMILES: C[C@@]1(c2c(F)cccc2NC(=O)c2ccncc2Cl)NNC2(C=CC(=O)C=C2)O1

BIRTHDAY: 2018-12-01T14:10:59.067494
ATC: J01F
- ANTIINFECTIVES FOR SYSTEMIC USE
- ANTIBACTERIALS FOR SYSTEMIC USE
- MACROLIDES, LINCOSAMIDES AND STREPTOGRAMINS
Synthesis Plan
FORMULA:C18H17F2N5O

SMILES: FC(F)[C@@H]1COC(n2cnc3c2CNC(c2cccnc2)=C3)=NC12CC2

BIRTHDAY: 2018-12-25T02:03:01.892372
ATC: N03A
- NERVOUS SYSTEM
- ANTIEPILEPTICS
- ANTIEPILEPTICS
Synthesis Plan
FORMULA:C25H31ClFN3O2

SMILES: C[C@H]1[C@@H]2CC[C@@H](O[C@@]2(C)c2ccc(NC(=O)c3ccc(Cl)cn3)c(F)c2)[C@@H]1NC(C)(C)C

BIRTHDAY: 2018-12-25T02:03:01.902621
ATC: J05A
- ANTIINFECTIVES FOR SYSTEMIC USE
- ANTIVIRALS FOR SYSTEMIC USE
- DIRECT ACTING ANTIVIRALS
Synthesis Plan
FORMULA:C17H20FN3O2

SMILES: CC(C)(C)c1cocc1-c1cncn1[C@@]12CN=C(CF)O[C@@H]1C2

BIRTHDAY: 2018-12-25T02:03:01.911258
ATC: M04A
- MUSCULO-SKELETAL SYSTEM
- ANTIGOUT PREPARATIONS
- ANTIGOUT PREPARATIONS
Synthesis Plan
FORMULA:C14H12F2N4O

SMILES: FCC1=NC[C@]2(n3ccnc3-c3ccnc(F)c3)C[C@@H]2O1

BIRTHDAY: 2018-12-25T02:03:01.919770
ATC: J04A
- ANTIINFECTIVES FOR SYSTEMIC USE
- ANTIMYCOBACTERIALS
- DRUGS FOR TREATMENT OF TUBERCULOSIS
Synthesis Plan
FORMULA:C14H12F2N4O

SMILES: FCC1=NC[C@@H]2C[C@@]2(n2ccnc2-c2ccncc2F)O1

BIRTHDAY: 2018-12-25T02:03:01.928862
ATC: J05A
- ANTIINFECTIVES FOR SYSTEMIC USE
- ANTIVIRALS FOR SYSTEMIC USE
- DIRECT ACTING ANTIVIRALS
Synthesis Plan
FORMULA:C24H28F3N3O3

SMILES: COc1cnc(C(=O)Nc2cccc(F)c2[C@]2(CF)[C@H]3O[C@@](C)(F)C[C@]2(C)[C@H](C)[C@H]3C)cn1

BIRTHDAY: 2018-12-25T02:03:01.939752
ATC: N06D
- NERVOUS SYSTEM
- PSYCHOANALEPTICS
- ANTI-DEMENTIA DRUGS
Synthesis Plan
FORMULA:C14H11ClF2N2O

SMILES: O=C(Nc1ccc(CCF)cc1F)c1cccnc1Cl

BIRTHDAY: 2018-12-25T02:03:01.947314
ATC: N02B
- NERVOUS SYSTEM
- ANALGESICS
- OTHER ANALGESICS AND ANTIPYRETICS
Synthesis Plan
FORMULA:C24H28ClF3N4O2

SMILES: C[C@H]([C@H](O)C(F)F)[C@]1(N)[C@H]2CC[C@@H]1[C@](C)(c1cccc(NC(=O)c3ccncc3Cl)c1F)NC2

BIRTHDAY: 2018-12-25T02:03:01.958613
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C21H19ClFN3O3

SMILES: C[C@]12OCC[C@H](CO1)[C@]2(C)c1c(F)cccc1NC(=O)c1c(Cl)cncc1C#N

BIRTHDAY: 2018-12-25T02:03:01.968860
ATC: R07A
- RESPIRATORY SYSTEM
- OTHER RESPIRATORY SYSTEM PRODUCTS
- OTHER RESPIRATORY SYSTEM PRODUCTS
Synthesis Plan
FORMULA:C23H21FN2O4S

SMILES: COc1ccccc1[C@]1(c2ccccc2-c2cncc(F)c2)CCCC(=O)S(=O)(=O)N1

BIRTHDAY: 2018-12-25T02:03:01.980243
ATC: N05B
- NERVOUS SYSTEM
- PSYCHOLEPTICS
- ANXIOLYTICS
Synthesis Plan
FORMULA:C25H34N2O3

SMILES: COc1cccc(C(=O)Nc2ccccc2[C@@H](CC(C)C)C(=O)NCC(C)(C)C)c1

BIRTHDAY: 2018-12-25T02:03:01.989207
ATC: G03D
- GENITO URINARY SYSTEM AND SEX HORMONES
- SEX HORMONES AND MODULATORS OF THE GENITAL SYSTEM
- PROGESTOGENS
Synthesis Plan
FORMULA:C23H27ClFN5O

SMILES: CN1C[C@@]2(CC(C)(C)[C@@](C)(c3cc(NC(=O)c4ccc(Cl)cn4)ccc3F)C2)N=C1N

BIRTHDAY: 2018-12-25T02:03:01.999416
ATC: D07A
- DERMATOLOGICALS
- CORTICOSTEROIDS, DERMATOLOGICAL PREPARATIONS
- CORTICOSTEROIDS, PLAIN
Synthesis Plan
FORMULA:C25H26N2O2S

SMILES: COc1ccccc1-c1ccccc1[C@@]1(c2ccccc2)N(C)C(=O)SN1C(C)C

BIRTHDAY: 2018-12-25T02:03:02.009048
ATC: J01X
- ANTIINFECTIVES FOR SYSTEMIC USE
- ANTIBACTERIALS FOR SYSTEMIC USE
- OTHER ANTIBACTERIALS
Synthesis Plan
FORMULA:C20H20ClFN4O5S

SMILES: C[C@@]1(c2cc(NC(=O)c3ccc(Cl)cn3)ccc2F)OC(=N)NS(=O)(=O)[C@@]12CCCCO2

BIRTHDAY: 2018-12-25T02:03:02.020542
ATC: L02B
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ENDOCRINE THERAPY
- HORMONE ANTAGONISTS AND RELATED AGENTS
Synthesis Plan
FORMULA:C16H12ClF5N4OS

SMILES: C[C@]1(c2cccc(F)c2NC(=O)c2cncc(Cl)c2)[SH]=NC(F)(F)NC1(F)F

BIRTHDAY: 2018-12-25T02:03:02.031651
ATC: G03A
- GENITO URINARY SYSTEM AND SEX HORMONES
- SEX HORMONES AND MODULATORS OF THE GENITAL SYSTEM
- HORMONAL CONTRACEPTIVES FOR SYSTEMIC USE
Synthesis Plan
FORMULA:C28H27ClFN3O2

SMILES: C[C@]1(c2cc(F)cc(NC(=O)c3ccnc(Cl)c3)c2)C[C@H]2CC[C@H]1[C@H]([C@@]13C=CC=C[C@H]1OC=N3)C2

BIRTHDAY: 2018-12-25T02:03:02.051432
ATC: J05A
- ANTIINFECTIVES FOR SYSTEMIC USE
- ANTIVIRALS FOR SYSTEMIC USE
- DIRECT ACTING ANTIVIRALS
Synthesis Plan
FORMULA:C18H17F2N5O

SMILES: FC(F)[C@H]1N=COC2(CC2)[C@@H]1n1cnc2c1CNC(c1cccnc1)=C2

BIRTHDAY: 2018-12-25T02:03:02.060904
ATC: N05C
- NERVOUS SYSTEM
- PSYCHOLEPTICS
- HYPNOTICS AND SEDATIVES
Synthesis Plan
FORMULA:C17H15F2N5O

SMILES: FC(F)C1=N[C@@]2(n3cnc4c3N[C@H](c3ccccn3)C=C4)C[C@@H]2CO1

BIRTHDAY: 2018-12-25T02:03:02.070285
ATC: N05A
- NERVOUS SYSTEM
- PSYCHOLEPTICS
- ANTIPSYCHOTICS
Synthesis Plan
FORMULA:C26H30ClFN6O2

SMILES: CO/N=C(/N)[C@]12CC[C@@H]3N[C@@H]1[C@H]1CC[C@@H]2N[C@H]1[C@@]3(C)c1c(F)cccc1NC(=O)c1cnccc1Cl

BIRTHDAY: 2018-12-03T02:39:05.800013
ATC: M03A
- MUSCULO-SKELETAL SYSTEM
- MUSCLE RELAXANTS
- MUSCLE RELAXANTS, PERIPHERALLY ACTING AGENTS
Synthesis Plan
FORMULA:C18H17F2N5O

SMILES: FC(F)[C@H]1CC2(CC2)N=C(n2cnc3c2N[C@@H](c2ccccn2)C=C3)O1

BIRTHDAY: 2018-12-03T02:39:05.809809
ATC: L04A
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- IMMUNOSUPPRESSANTS
- IMMUNOSUPPRESSANTS
Synthesis Plan
FORMULA:C17H15F2N5O

SMILES: FC(F)[C@@H]1N=C(n2cnc3c2CNC(c2ccncc2)=C3)O[C@@H]2C[C@@H]21

BIRTHDAY: 2018-12-03T02:39:05.828555
ATC: N05C
- NERVOUS SYSTEM
- PSYCHOLEPTICS
- HYPNOTICS AND SEDATIVES
Synthesis Plan
FORMULA:C14H10ClF3N2O

SMILES: O=C(Nc1c(F)cccc1CC(F)F)c1ccncc1Cl

BIRTHDAY: 2018-12-03T02:39:05.845351
ATC: N07C
- NERVOUS SYSTEM
- OTHER NERVOUS SYSTEM DRUGS
- ANTIVERTIGO PREPARATIONS
Synthesis Plan
FORMULA:C15H14F2N4O

SMILES: FC[C@H]1COC(n2cnc(-c3cccnc3F)c2)=NC12CC2

BIRTHDAY: 2018-12-03T02:39:05.853763
ATC: C01B
- CARDIOVASCULAR SYSTEM
- CARDIAC THERAPY
- ANTIARRHYTHMICS, CLASS I AND III
Synthesis Plan
FORMULA:C21H23F2N3O4S

SMILES: COc1ccc(C(=O)Nc2cccc([C@]3(C(F)F)CS(=O)(=O)C(C)(C)C(=N)N3)c2)cc1

BIRTHDAY: 2018-12-03T02:39:05.864144
ATC: J05A
- ANTIINFECTIVES FOR SYSTEMIC USE
- ANTIVIRALS FOR SYSTEMIC USE
- DIRECT ACTING ANTIVIRALS
Synthesis Plan
FORMULA:C29H31F2N3O3

SMILES: COc1ccccc1[C@@]1(c2cccc(F)c2)NCC(=O)N1C(C)(C)[C@@H](C)C(=O)NCc1cccc(F)c1

BIRTHDAY: 2018-12-03T02:39:05.876002
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C15H9ClF4N2O

SMILES: C=C(c1cc(NC(=O)c2cccnc2Cl)ccc1F)C(F)(F)F

BIRTHDAY: 2018-12-03T02:39:05.884536
ATC: C03X
- CARDIOVASCULAR SYSTEM
- DIURETICS
- OTHER DIURETICS
Synthesis Plan
FORMULA:C30H25F3N4O

SMILES: COc1cccc([C@]2(c3ccc(-c4cccnc4F)cc3)[C@@H]3CN4CN2CN(C3)c2c4ccc(F)c2F)c1

BIRTHDAY: 2018-12-03T02:39:05.896374
ATC: A07A
- ALIMENTARY TRACT AND METABOLISM
- ANTIDIARRHEALS, INTESTINAL ANTIINFLAMMATORY/ANTIINFECTIVE AGENTS
- INTESTINAL ANTIINFECTIVES
Synthesis Plan
FORMULA:C18H16ClF3N2O2S

SMILES: CC1(C)SO[C@](C)(c2cc(NC(=O)c3ccc(Cl)cn3)ccc2F)C1(F)F

BIRTHDAY: 2018-12-03T02:39:05.906322
ATC: L01A
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- ALKYLATING AGENTS
Synthesis Plan
FORMULA:C17H16ClFN2O3S

SMILES: C[C@@]1(c2cccc(F)c2NC(=O)c2cccc(Cl)n2)CCCS1(=O)=O

BIRTHDAY: 2018-12-03T02:39:05.915856
ATC: R06A
- RESPIRATORY SYSTEM
- ANTIHISTAMINES FOR SYSTEMIC USE
- ANTIHISTAMINES FOR SYSTEMIC USE
Synthesis Plan
FORMULA:C18H17F2N5O

SMILES: FC(F)[C@H]1COC(n2cnc3c2CNC(c2cccnc2)=C3)=NC12CC2

BIRTHDAY: 2018-12-03T02:39:05.925200
ATC: N03A
- NERVOUS SYSTEM
- ANTIEPILEPTICS
- ANTIEPILEPTICS
Synthesis Plan
FORMULA:C26H23ClF2N2OS

SMILES: C[C@@]1(c2c(F)cccc2NC(=O)c2ncccc2Cl)C[C@@H]2CCC[C@@]1(c1ccccc1F)S2

BIRTHDAY: 2018-12-03T02:39:05.943971
ATC: N02B
- NERVOUS SYSTEM
- ANALGESICS
- OTHER ANALGESICS AND ANTIPYRETICS
Synthesis Plan
FORMULA:C22H23ClFN3O

SMILES: CC1(c2cc(NC(=O)c3cncc(Cl)c3)ccc2F)[C@@H]2CC3C[C@@H]1CN(C3)C2

BIRTHDAY: 2018-11-30T03:41:02.881981
ATC: G03X
- GENITO URINARY SYSTEM AND SEX HORMONES
- SEX HORMONES AND MODULATORS OF THE GENITAL SYSTEM
- OTHER SEX HORMONES AND MODULATORS OF THE GENITAL SYSTEM
Synthesis Plan
FORMULA:C20H15F3O

SMILES: FC(F)(F)Oc1ccc(-c2ccc(Cc3ccccc3)cc2)cc1

BIRTHDAY: 2018-11-30T03:41:02.889427
ATC: N07C
- NERVOUS SYSTEM
- OTHER NERVOUS SYSTEM DRUGS
- ANTIVERTIGO PREPARATIONS
Synthesis Plan
FORMULA:C14H11ClF2N2O

SMILES: O=C(Nc1cc(CCF)ccc1F)c1ncccc1Cl

BIRTHDAY: 2018-11-30T03:41:02.897141
ATC: B01A
- BLOOD AND BLOOD FORMING ORGANS
- ANTITHROMBOTIC AGENTS
- ANTITHROMBOTIC AGENTS
Synthesis Plan
FORMULA:C17H16ClFN2O3

SMILES: C[C@@]1(c2cccc(F)c2NC(=O)c2ccncc2Cl)COCCO1

BIRTHDAY: 2018-11-30T03:41:02.906039
ATC: J01F
- ANTIINFECTIVES FOR SYSTEMIC USE
- ANTIBACTERIALS FOR SYSTEMIC USE
- MACROLIDES, LINCOSAMIDES AND STREPTOGRAMINS
Synthesis Plan
FORMULA:C25H21F3N2O3

SMILES: COc1ccc([C@@]2(c3ccccc3-c3cnccc3F)O[C@]3(N)C[C@H](C2=O)C(F)(F)C3)cc1

BIRTHDAY: 2018-11-30T03:41:02.925307
ATC: J04A
- ANTIINFECTIVES FOR SYSTEMIC USE
- ANTIMYCOBACTERIALS
- DRUGS FOR TREATMENT OF TUBERCULOSIS
Synthesis Plan
FORMULA:C17H15F2N5O

SMILES: FC(F)C1=N[C@]2(n3cnc4c3N[C@@H](c3ccccn3)C=C4)C[C@@H]2CO1

BIRTHDAY: 2018-11-30T03:41:02.934593
ATC: N05A
- NERVOUS SYSTEM
- PSYCHOLEPTICS
- ANTIPSYCHOTICS
Synthesis Plan
FORMULA:C20H22ClFN4O

SMILES: C[C@]1(c2cc(NC(=O)c3ncccc3Cl)ccc2F)C[C@H]2CN(CCN2)C1

BIRTHDAY: 2018-11-30T03:41:02.951994
ATC: P03B
- ANTIPARASITIC PRODUCTS, INSECTICIDES AND REPELLENTS
- ECTOPARASITICIDES, INCL. SCABICIDES, INSECTICIDES AND REPELLENTS
- INSECTICIDES AND REPELLENTS
Synthesis Plan
FORMULA:C28H33ClFN3O3

SMILES: C[C@]1(c2cc(F)cc(NC(=O)c3ccncc3Cl)c2)CCCCO[C@H]2C=CC=C[C@H]2NCCOCC1

BIRTHDAY: 2018-11-30T03:41:02.962383
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C17H14F3N5O

SMILES: Fc1cc([C@H]2C=Cc3ncn([C@H]4N=C(C(F)F)O[C@@H]5C[C@@H]54)c3N2)ccn1

BIRTHDAY: 2018-11-30T03:41:02.972542
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C30H38FN5O2

SMILES: COc1ccccc1[C@@]1(c2ccc(-c3ccnc(F)c3)cc2)CCNCCNCCNCCCNC(=O)C1

BIRTHDAY: 2018-11-30T03:41:02.985084
ATC: C10A
- CARDIOVASCULAR SYSTEM
- LIPID MODIFYING AGENTS
- LIPID MODIFYING AGENTS, PLAIN
Synthesis Plan
FORMULA:C14H12F2N4O

SMILES: FCC1=NC[C@@]2(n3cncc3-c3ccncc3F)C[C@@H]2O1

BIRTHDAY: 2018-11-30T03:41:02.993677
ATC: B03B
- BLOOD AND BLOOD FORMING ORGANS
- ANTIANEMIC PREPARATIONS
- VITAMIN B12 AND FOLIC ACID
Synthesis Plan
FORMULA:C19H14F3NO

SMILES: Fc1cc(-c2ccccc2Cc2ccccc2OC(F)F)ccn1

BIRTHDAY: 2018-11-30T03:41:03.028022
ATC: N02C
- NERVOUS SYSTEM
- ANALGESICS
- ANTIMIGRAINE PREPARATIONS
Synthesis Plan
FORMULA:C22H24F2N2O2S2

SMILES: COc1ccc(C(=O)Nc2cccc([C@@]3(C(F)F)SC4(CC4)NSC3(C)C)c2)cc1

BIRTHDAY: 2018-11-19T08:15:53.318603
ATC: N03A
- NERVOUS SYSTEM
- ANTIEPILEPTICS
- ANTIEPILEPTICS
Synthesis Plan
FORMULA:C18H17F2N5O

SMILES: FC(F)[C@@H]1[C@@H](n2cnc3c2C=CN[C@H]3c2ccncc2)N=COC12CC2

BIRTHDAY: 2018-11-19T08:15:53.328223
ATC: C10A
- CARDIOVASCULAR SYSTEM
- LIPID MODIFYING AGENTS
- LIPID MODIFYING AGENTS, PLAIN
Synthesis Plan
FORMULA:C14H11ClF2N2O

SMILES: O=C(Nc1cc(F)cc(CCF)c1)c1ccncc1Cl

BIRTHDAY: 2018-11-19T08:15:53.335926
ATC: C02A
- CARDIOVASCULAR SYSTEM
- ANTIHYPERTENSIVES
- ANTIADRENERGIC AGENTS, CENTRALLY ACTING
Synthesis Plan
FORMULA:C17H15ClF3N3O2S

SMILES: C[C@]1(c2cc(NC(=O)c3ccc(Cl)cn3)ccc2F)CSNCC(F)(F)O1

BIRTHDAY: 2018-11-19T08:15:53.345906
ATC: N03A
- NERVOUS SYSTEM
- ANTIEPILEPTICS
- ANTIEPILEPTICS
Synthesis Plan
FORMULA:C19H17Cl2NO5

SMILES: CC1=CC(=O)C2=C3NCCOC(O)(O)C=C3O[C@@]2(c2ccc(Cl)cc2Cl)C1

BIRTHDAY: 2018-11-19T08:15:53.355944
ATC: A11D
- ALIMENTARY TRACT AND METABOLISM
- VITAMINS
- VITAMIN B1, PLAIN AND IN COMBINATION WITH VITAMIN B6 AND B12
Synthesis Plan
FORMULA:C29H31F2N3O3

SMILES: COc1ccccc1[C@]1(c2cccc(F)c2)NCC(=O)N1C(C)(C)[C@H](C)C(=O)NCc1ccccc1F

BIRTHDAY: 2018-11-19T08:15:53.368017
ATC: N07B
- NERVOUS SYSTEM
- OTHER NERVOUS SYSTEM DRUGS
- DRUGS USED IN ADDICTIVE DISORDERS
Synthesis Plan
FORMULA:C19H10ClF3N2O2

SMILES: O=C(c1ccc(F)cc1F)c1cc(F)ccc1NC(=O)c1cccnc1Cl

BIRTHDAY: 2018-11-19T08:15:53.377491
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C24H20ClF3N2O2S

SMILES: C[C@@H]1CC[C@](c2cc(F)ccc2F)(c2c(F)cccc2NC(=O)c2ccncc2Cl)C[S@@+]1[O-]

BIRTHDAY: 2018-11-19T08:15:53.389165
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C31H37FN2O3

SMILES: COc1ccccc1-c1ccccc1[C@@]1(c2ccccc2F)COCCCN(C)CCCCNC(=O)C1

BIRTHDAY: 2018-11-19T08:15:53.400821
ATC: N05C
- NERVOUS SYSTEM
- PSYCHOLEPTICS
- HYPNOTICS AND SEDATIVES
Synthesis Plan
FORMULA:C27H20F2N2O3

SMILES: COc1ccc([C@@]2(c3ccc(-c4ccc(F)cn4)cc3)OC(=O)CNc3ccc(F)cc32)cc1

BIRTHDAY: 2018-11-19T08:15:53.412235
ATC: S01B
- SENSORY ORGANS
- OPHTHALMOLOGICALS
- ANTIINFLAMMATORY AGENTS
Synthesis Plan
FORMULA:C22H21ClF4N4O2

SMILES: C[C@@]1(c2c(F)cccc2NC(=O)c2ccncc2Cl)[C@@H](C(F)(F)F)C[C@@H]2CN[C@]1(N)C(=O)C2

BIRTHDAY: 2018-11-19T08:15:53.424783
ATC: N07B
- NERVOUS SYSTEM
- OTHER NERVOUS SYSTEM DRUGS
- DRUGS USED IN ADDICTIVE DISORDERS
Synthesis Plan
FORMULA:C6H9FN2O

SMILES: N[C@@H]1N=CO[C@@H]2C[C@@]12CF

BIRTHDAY: 2018-11-19T08:15:53.431011
ATC: N05C
- NERVOUS SYSTEM
- PSYCHOLEPTICS
- HYPNOTICS AND SEDATIVES
Synthesis Plan
FORMULA:C15H24F4N2O2

SMILES: CC(C)C[C@@H](NC(=O)C(C)(C)C)C(=O)N1C(F)(F)CCC1(F)F

BIRTHDAY: 2018-11-19T08:15:53.440120
ATC: J05A
- ANTIINFECTIVES FOR SYSTEMIC USE
- ANTIVIRALS FOR SYSTEMIC USE
- DIRECT ACTING ANTIVIRALS
Synthesis Plan
FORMULA:C29H28F3N3O2

SMILES: O=C(Nc1ccccc1C(=O)Nc1ccccc1[C@]1(C(F)(F)F)C[C@H]2CCC[C@H]1CC2)c1ccccn1

BIRTHDAY: 2018-11-19T08:15:53.462062
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C33H34N2O2

SMILES: COc1ccc(-c2ccc([C@@]3(c4ccccc4)CCCCC(=O)N(Cc4cccnc4)CC3)cc2)cc1

BIRTHDAY: 2018-11-19T08:15:53.473388
ATC: N06B
- NERVOUS SYSTEM
- PSYCHOANALEPTICS
- PSYCHOSTIMULANTS, AGENTS USED FOR ADHD AND NOOTROPICS
Synthesis Plan
FORMULA:C17H15F2N5O

SMILES: FC(F)C1=N[C@@]2(n3cnc4c3N[C@@H](c3ccccn3)C=C4)C[C@H]2CO1

BIRTHDAY: 2018-11-19T08:15:53.482864
ATC: N05A
- NERVOUS SYSTEM
- PSYCHOLEPTICS
- ANTIPSYCHOTICS
Synthesis Plan
FORMULA:C14H12F2N4O

SMILES: FCC1=NC[C@]2(n3ccnc3-c3ccnc(F)c3)C[C@H]2O1

BIRTHDAY: 2018-11-19T08:15:53.491333
ATC: J04A
- ANTIINFECTIVES FOR SYSTEMIC USE
- ANTIMYCOBACTERIALS
- DRUGS FOR TREATMENT OF TUBERCULOSIS
Synthesis Plan
FORMULA:C24H20F5NOS2

SMILES: Fc1cccnc1-c1cccc([C@@]2(c3ccc(OC(F)F)cc3)CCSC(F)(F)CCS2)c1

BIRTHDAY: 2018-11-19T08:15:53.503375
ATC: A03A
- ALIMENTARY TRACT AND METABOLISM
- DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS
- DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS
Synthesis Plan
FORMULA:C22H25ClFN3O

SMILES: C[C@@]1(c2cc(F)cc(NC(=O)c3ccncc3Cl)c2)CC[C@H]2CCC[C@@H]1NC2

BIRTHDAY: 2018-11-19T08:15:53.512418
ATC: P02D
- ANTIPARASITIC PRODUCTS, INSECTICIDES AND REPELLENTS
- ANTHELMINTICS
- ANTICESTODALS
Synthesis Plan
FORMULA:C24H20ClF3N2O

SMILES: C[C@]1(c2ccc(NC(=O)c3ccc(Cl)cn3)c(F)c2)[C@H]2[C@@H]3[C@@H]4C[C@@H]2[C@@H]2[C@@H]4[C@H]([C@@H]21)C3(F)F

BIRTHDAY: 2018-11-19T08:15:53.522809
ATC: C01D
- CARDIOVASCULAR SYSTEM
- CARDIAC THERAPY
- VASODILATORS USED IN CARDIAC DISEASES
Synthesis Plan
FORMULA:C14H10ClF3N2O

SMILES: O=C(Nc1ccc(F)c(CC(F)F)c1)c1ccc(Cl)nc1

BIRTHDAY: 2018-11-19T08:15:53.539465
ATC: M04A
- MUSCULO-SKELETAL SYSTEM
- ANTIGOUT PREPARATIONS
- ANTIGOUT PREPARATIONS
Synthesis Plan
FORMULA:C17H12ClF5N2O

SMILES: CC1(c2cccc(F)c2NC(=O)c2ccncc2Cl)C(F)(F)CC1(F)F

BIRTHDAY: 2018-11-19T08:15:53.549367
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C25H24FNO3

SMILES: COc1ccccc1[C@@]1(c2ccccc2-c2cnccc2F)CO[C@H]2CCC[C@H]1O2

BIRTHDAY: 2018-11-19T08:15:53.559621
ATC: L01D
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- CYTOTOXIC ANTIBIOTICS AND RELATED SUBSTANCES
Synthesis Plan
FORMULA:C24H36N4O6

SMILES: C[C@H](C(=O)NCCCCCCCCCC[C@H]1C[C@H]2O[C@H](O1)O[C@@H]2NC(=O)c1ccco1)C1N=N1

BIRTHDAY: 2018-11-19T08:15:53.570327
ATC: C02C
- CARDIOVASCULAR SYSTEM
- ANTIHYPERTENSIVES
- ANTIADRENERGIC AGENTS, PERIPHERALLY ACTING
Synthesis Plan
FORMULA:C22H23ClFN3O

SMILES: C[C@]1(c2c(F)cccc2NC(=O)c2ccnc(Cl)c2)[C@@H]2CC[C@H]3CN1CC[C@H]32

BIRTHDAY: 2018-11-19T08:15:53.590025
ATC: N02B
- NERVOUS SYSTEM
- ANALGESICS
- OTHER ANALGESICS AND ANTIPYRETICS
Synthesis Plan
FORMULA:C44H54F2N6O7S

SMILES: COc1ccc(C(=O)Nc2ccc([C@]3(C(F)F)C[C@@H](N4CCNCCCNCc5cccc(n5)C5=N[C@@H](CS5)C4)OC(=O)C[C@@H]4CCC[C@@]5(C[C@H](CCO5)O3)O4)cc2)cc1

BIRTHDAY: 2018-11-19T08:15:53.612176
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C20H16ClFN4O3

SMILES: C[C@]1(c2ccc(NC(=O)c3cccnc3Cl)c(F)c2)NNC2(C=CC(=O)C=C2)O1

BIRTHDAY: 2018-11-19T08:15:53.622125
ATC: V03A
- VARIOUS
- ALL OTHER THERAPEUTIC PRODUCTS
- ALL OTHER THERAPEUTIC PRODUCTS
Synthesis Plan
FORMULA:C20H21ClFN3O

SMILES: C[C@@]1(c2c(F)cccc2NC(=O)c2cnccc2Cl)CC2CCN1CC2

BIRTHDAY: 2018-11-19T08:15:53.631343
ATC: P03B
- ANTIPARASITIC PRODUCTS, INSECTICIDES AND REPELLENTS
- ECTOPARASITICIDES, INCL. SCABICIDES, INSECTICIDES AND REPELLENTS
- INSECTICIDES AND REPELLENTS
Synthesis Plan
FORMULA:C22H25ClFN3O2S

SMILES: CC1(C)N[C@@]2(CCO2)SCC[C@@]1(C)c1c(F)cccc1NC(=O)c1cnccc1Cl

BIRTHDAY: 2018-11-19T08:15:53.641596
ATC: N02B
- NERVOUS SYSTEM
- ANALGESICS
- OTHER ANALGESICS AND ANTIPYRETICS
Synthesis Plan
FORMULA:C26H36ClFN6O

SMILES: C[C@]1(c2cc(NC(=O)c3cccnc3Cl)ccc2F)CNCCNCCNC[C@H]2C[C@H]2CCNC1

BIRTHDAY: 2018-11-19T08:15:53.652541
ATC: P01C
- ANTIPARASITIC PRODUCTS, INSECTICIDES AND REPELLENTS
- ANTIPROTOZOALS
- AGENTS AGAINST LEISHMANIASIS AND TRYPANOSOMIASIS
Synthesis Plan
FORMULA:C25H22ClFN2O2

SMILES: C[C@@]1(c2cc(NC(=O)c3ccc(Cl)cn3)ccc2F)O[C@]23C=CC=C[C@]24C[C@H](C[C@H]41)C3

BIRTHDAY: 2018-11-19T08:15:53.662402
ATC: C01D
- CARDIOVASCULAR SYSTEM
- CARDIAC THERAPY
- VASODILATORS USED IN CARDIAC DISEASES
Synthesis Plan
FORMULA:C22H26ClFN4O2

SMILES: CCCC[C@@H]1CCN[C@@](C)(c2cc(NC(=O)c3ccc(Cl)cn3)ccc2F)NC1=O

BIRTHDAY: 2018-11-19T08:15:53.672062
ATC: N05C
- NERVOUS SYSTEM
- PSYCHOLEPTICS
- HYPNOTICS AND SEDATIVES
Synthesis Plan
FORMULA:C25H19ClF4N2O2

SMILES: C[C@@]1(c2cccc(F)c2NC(=O)c2ccnc(Cl)c2)[C@H]2[C@H]3[C@H]4[C@@H]5O[C@H]3[C@H]3[C@H]2[C@H]([C@H]41)[C@]53C(F)(F)F

BIRTHDAY: 2018-11-19T08:15:53.684306
ATC: A10B
- ALIMENTARY TRACT AND METABOLISM
- DRUGS USED IN DIABETES
- BLOOD GLUCOSE LOWERING DRUGS, EXCL. INSULINS
Synthesis Plan
FORMULA:C14H10ClF3N2O

SMILES: O=C(Nc1ccc(F)c(CC(F)F)c1)c1cccnc1Cl

BIRTHDAY: 2018-11-19T08:15:53.692628
ATC: A07A
- ALIMENTARY TRACT AND METABOLISM
- ANTIDIARRHEALS, INTESTINAL ANTIINFLAMMATORY/ANTIINFECTIVE AGENTS
- INTESTINAL ANTIINFECTIVES
Synthesis Plan
FORMULA:C14H10ClF3N2O

SMILES: O=C(Nc1cc(F)ccc1CC(F)F)c1ccncc1Cl

BIRTHDAY: 2018-11-19T08:15:53.701009
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C27H28ClFN4O

SMILES: C[C@]1(c2cccc(F)c2NC(=O)c2ccncc2Cl)CC[C@@H]2CC[C@](N)(c3ccccc3)[C@H]1N2

BIRTHDAY: 2018-11-19T08:15:53.712976
ATC: C10A
- CARDIOVASCULAR SYSTEM
- LIPID MODIFYING AGENTS
- LIPID MODIFYING AGENTS, PLAIN
Synthesis Plan
FORMULA:C30H30O2

SMILES: COc1ccc(-c2ccc([C@]3(c4ccccc4)C[C@@H]4C(=O)[C@@H]5C[C@@H]3[C@H]4C5(C)C)cc2)cc1

BIRTHDAY: 2018-11-19T08:15:53.721777
ATC: A05A
- ALIMENTARY TRACT AND METABOLISM
- BILE AND LIVER THERAPY
- BILE THERAPY
Synthesis Plan
FORMULA:C33H40N4O3

SMILES: Cc1ccc2cc1CNCCN[C@]1(C(=O)Nc3ccccc3C(C)C)CN(CC1=O)C(C)(C)c1cccc(c1)O2

BIRTHDAY: 2018-11-19T08:15:53.734637
ATC: N06B
- NERVOUS SYSTEM
- PSYCHOANALEPTICS
- PSYCHOSTIMULANTS, AGENTS USED FOR ADHD AND NOOTROPICS
Synthesis Plan
FORMULA:C24H30ClFN4O2

SMILES: CC1(C)CN(C2CCOCC2)C[C@@](C)(c2cc(NC(=O)c3ncccc3Cl)ccc2F)N1

BIRTHDAY: 2018-11-19T08:15:53.744775
ATC: C10A
- CARDIOVASCULAR SYSTEM
- LIPID MODIFYING AGENTS
- LIPID MODIFYING AGENTS, PLAIN
Synthesis Plan
FORMULA:C14H12F2N4O

SMILES: FCC1=NC[C@H]2C[C@]2(n2ccnc2-c2ccncc2F)O1

BIRTHDAY: 2018-11-19T08:15:53.753388
ATC: J05A
- ANTIINFECTIVES FOR SYSTEMIC USE
- ANTIVIRALS FOR SYSTEMIC USE
- DIRECT ACTING ANTIVIRALS
Synthesis Plan
FORMULA:C22H27N7O2

SMILES: N#CC[C@H](C#N)c1ccc(Nc2ncc3nc2OCCCCCOCCNCN3)cc1

BIRTHDAY: 2018-11-19T08:15:53.763466
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C29H32FNO2

SMILES: COc1cccc([C@@H](c2cccc(F)c2)c2c3cccc2CCNCC(=O)CCCCC3)c1

BIRTHDAY: 2018-11-19T08:15:53.774211
ATC: N02B
- NERVOUS SYSTEM
- ANALGESICS
- OTHER ANALGESICS AND ANTIPYRETICS
Synthesis Plan
FORMULA:C16H14ClFN2O2

SMILES: C[C@]1(c2cccc(F)c2NC(=O)c2ccncc2Cl)CCO1

BIRTHDAY: 2018-11-19T08:15:53.782632
ATC: C10A
- CARDIOVASCULAR SYSTEM
- LIPID MODIFYING AGENTS
- LIPID MODIFYING AGENTS, PLAIN
Synthesis Plan
FORMULA:C23H27ClFN3O

SMILES: CN1C[C@H]2C[C@@H]1C[C@](C)(c1ccc(NC(=O)c3ccc(Cl)cn3)cc1F)C2(C)C

BIRTHDAY: 2018-11-19T08:15:53.791692
ATC: M01A
- MUSCULO-SKELETAL SYSTEM
- ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS
- ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS
Synthesis Plan
FORMULA:C22H23ClF3N3O

SMILES: C[C@@]1(c2ccc(F)cc2NC(=O)c2ccnc(Cl)c2)[C@@H]2CCCN1C(F)(F)CCC2

BIRTHDAY: 2018-11-19T08:15:53.802053
ATC: A03F
- ALIMENTARY TRACT AND METABOLISM
- DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS
- PROPULSIVES
Synthesis Plan
FORMULA:C26H30ClF2N3O

SMILES: CC(C)[C@@H](F)[C@@]1(c2cc(NC(=O)c3ccncc3Cl)ccc2F)CC[C@@H]2C[C@@H]3CCN2C[C@H]31

BIRTHDAY: 2018-11-19T08:15:53.813172
ATC: J05A
- ANTIINFECTIVES FOR SYSTEMIC USE
- ANTIVIRALS FOR SYSTEMIC USE
- DIRECT ACTING ANTIVIRALS
Synthesis Plan
FORMULA:C35H39ClFN3O4

SMILES: C[C@@H]1[C@H]2O[C@@H](C[C@]2(C)c2c(F)cccc2NC(=O)c2ccnc(Cl)c2)[C@@]12CCCCC(=O)CNCCc1ccc(cc1)OC2

BIRTHDAY: 2018-11-19T08:15:53.826042
ATC: C02D
- CARDIOVASCULAR SYSTEM
- ANTIHYPERTENSIVES
- ARTERIOLAR SMOOTH MUSCLE, AGENTS ACTING ON
Synthesis Plan
FORMULA:C21H17FO2

SMILES: COc1ccc(-c2cccc([C@@]3(c4cccc(F)c4)CO3)c2)cc1

BIRTHDAY: 2018-11-19T08:15:53.833879
ATC: N04B
- NERVOUS SYSTEM
- ANTI-PARKINSON DRUGS
- DOPAMINERGIC AGENTS
Synthesis Plan
FORMULA:C17H15F2N5O

SMILES: FC(F)C1=N[C@H](n2cnc3c2C=C[C@@H](c2ccccn2)N3)[C@H]2C[C@@H]2O1

BIRTHDAY: 2018-11-19T08:15:53.851944
ATC: R03D
- RESPIRATORY SYSTEM
- DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES
- OTHER SYSTEMIC DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES
Synthesis Plan
FORMULA:C19H19ClFN3O

SMILES: [CH2-][C@@H]1C[CH+][C@](C)(c2cc(F)cc(NC(=O)c3ccncc3Cl)c2)CN1

BIRTHDAY: 2018-11-19T08:15:53.861028
ATC: N05A
- NERVOUS SYSTEM
- PSYCHOLEPTICS
- ANTIPSYCHOTICS
Synthesis Plan
FORMULA:C7H11FN2O

SMILES: N[C@H]1OC(CF)=NCC12CC2

BIRTHDAY: 2018-11-19T08:15:53.867199
ATC: J05A
- ANTIINFECTIVES FOR SYSTEMIC USE
- ANTIVIRALS FOR SYSTEMIC USE
- DIRECT ACTING ANTIVIRALS
Synthesis Plan
FORMULA:C22H23ClF3N3O2S2

SMILES: C[C@@H]1C[C@@]2(CCO1)S[C@@](C)(c1ccc(NC(=O)c3ccc(Cl)cn3)cc1F)NS[C@@H]2C(F)F

BIRTHDAY: 2018-11-19T08:15:53.878356
ATC: M04A
- MUSCULO-SKELETAL SYSTEM
- ANTIGOUT PREPARATIONS
- ANTIGOUT PREPARATIONS
Synthesis Plan
FORMULA:C21H22N4O3S

SMILES: CC(C)c1ccccc1NC(=O)c1nccc2c1S(=O)(=O)N[C@@]1(N)C=CC=C[C@@H]21

BIRTHDAY: 2018-11-19T08:15:53.897895
ATC: N06D
- NERVOUS SYSTEM
- PSYCHOANALEPTICS
- ANTI-DEMENTIA DRUGS
Synthesis Plan
FORMULA:C14H11ClF2N2O

SMILES: O=C(Nc1ccc(F)c(CCF)c1)c1ncccc1Cl

BIRTHDAY: 2018-11-19T08:15:53.905751
ATC: V03A
- VARIOUS
- ALL OTHER THERAPEUTIC PRODUCTS
- ALL OTHER THERAPEUTIC PRODUCTS
Synthesis Plan
FORMULA:C24H33F2N7O3

SMILES: CC(C)(NC(=O)[C@]1(C(=O)c2cccc(F)c2F)[C@H]2CN[C@@H](N)N1CNC2=O)N1CC=CNCCCC1

BIRTHDAY: 2018-11-19T08:15:53.919541
ATC: M01A
- MUSCULO-SKELETAL SYSTEM
- ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS
- ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS
Synthesis Plan
FORMULA:C17H15F2N5O

SMILES: FC(F)C1=N[C@H](n2cnc3c2N[C@@H](c2ccccn2)C=C3)[C@H]2C[C@@H]2O1

BIRTHDAY: 2018-11-19T08:15:53.929433
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C20H22N2O

SMILES: CC(C)c1ccc(NC(=O)c2nccc3c2CC2CC3C2)cc1

BIRTHDAY: 2018-11-19T08:15:53.936833
ATC: A10X
- ALIMENTARY TRACT AND METABOLISM
- DRUGS USED IN DIABETES
- OTHER DRUGS USED IN DIABETES
Synthesis Plan
FORMULA:C24H30ClFN6O3

SMILES: C[C@H]1CNCCNC(=O)[C@H](C)NC(=O)C[C@@](C)(c2cc(NC(=O)c3cncc(Cl)c3)ccc2F)N1

BIRTHDAY: 2018-11-19T08:15:53.948312
ATC: G03X
- GENITO URINARY SYSTEM AND SEX HORMONES
- SEX HORMONES AND MODULATORS OF THE GENITAL SYSTEM
- OTHER SEX HORMONES AND MODULATORS OF THE GENITAL SYSTEM
Synthesis Plan
FORMULA:C31H36FN5O2

SMILES: COc1ccccc1[C@]1(c2ccccc2-c2ccncc2F)N(CC(C)C)C(=O)N1C[C@]1(C)C2CNC1NC2

BIRTHDAY: 2018-11-19T08:15:53.962287
ATC: H03A
- SYSTEMIC HORMONAL PREPARATIONS, EXCL. SEX HORMONES AND INSULINS
- THYROID THERAPY
- THYROID PREPARATIONS
Synthesis Plan
FORMULA:C17H15F2N5O

SMILES: FC(F)C1=N[C@H](n2cnc3c2N[C@@H](c2ccccn2)C=C3)[C@H]2C[C@H]2O1

BIRTHDAY: 2018-11-19T08:15:53.972227
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C18H17ClFN3O3S

SMILES: CN1[C@@H]2C[C@@H]2[C@@](C)(c2c(F)cccc2NC(=O)c2ccncc2Cl)S1(=O)=O

BIRTHDAY: 2018-11-19T08:15:53.982493
ATC: G03B
- GENITO URINARY SYSTEM AND SEX HORMONES
- SEX HORMONES AND MODULATORS OF THE GENITAL SYSTEM
- ANDROGENS
Synthesis Plan
FORMULA:C15H18N2O2

SMILES: CC(C)(C)c1ccccc1NC(=O)[C@H]1C=NC=CO1

BIRTHDAY: 2018-11-19T08:15:53.989753
ATC: N02B
- NERVOUS SYSTEM
- ANALGESICS
- OTHER ANALGESICS AND ANTIPYRETICS
Synthesis Plan
FORMULA:C17H17ClFN5O2

SMILES: CN1CC(=O)NN[C@]1(C)c1cc(NC(=O)c2ccc(Cl)cn2)ccc1F

BIRTHDAY: 2018-11-19T08:15:53.999306
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C20H22ClFN4OS

SMILES: C[C@]1(c2ccc(F)cc2NC(=O)c2ccncc2Cl)CCCC2(CC2)N(N)S1

BIRTHDAY: 2018-11-19T08:15:54.009325
ATC: A11H
- ALIMENTARY TRACT AND METABOLISM
- VITAMINS
- OTHER PLAIN VITAMIN PREPARATIONS
Synthesis Plan
FORMULA:C22H26ClFN4O

SMILES: CC1(C)CC[C@H]2NC[C@@]1(N)[C@@]2(C)c1cccc(F)c1NC(=O)c1ccncc1Cl

BIRTHDAY: 2018-11-19T08:15:54.019264
ATC: N05B
- NERVOUS SYSTEM
- PSYCHOLEPTICS
- ANXIOLYTICS
Synthesis Plan
FORMULA:C17H15F2N5O

SMILES: FC(F)[C@@]12C[C@H]1COC(n1cnc3c1CNC=C3c1cccnc1)=N2

BIRTHDAY: 2018-11-19T08:15:54.028730
ATC: S01E
- SENSORY ORGANS
- OPHTHALMOLOGICALS
- ANTIGLAUCOMA PREPARATIONS AND MIOTICS
Synthesis Plan
FORMULA:C15H13ClFN3O

SMILES: C[C@@]1(c2ccc(NC(=O)c3cccnc3Cl)c(F)c2)CN1

BIRTHDAY: 2018-11-19T08:15:54.036658
ATC: M01A
- MUSCULO-SKELETAL SYSTEM
- ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS
- ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS
Synthesis Plan
FORMULA:C14H12F2N4O

SMILES: FCC1=NC[C@@]2(n3ccnc3-c3cnccc3F)C[C@H]2O1

BIRTHDAY: 2018-11-19T08:15:54.045369
ATC: J04A
- ANTIINFECTIVES FOR SYSTEMIC USE
- ANTIMYCOBACTERIALS
- DRUGS FOR TREATMENT OF TUBERCULOSIS
Synthesis Plan
FORMULA:C18H17F2N5O

SMILES: FC(F)[C@H]1COC(n2cnc3c2C=C(c2cccnc2)NC3)=NC12CC2

BIRTHDAY: 2018-11-19T08:15:54.054968
ATC: V08A
- VARIOUS
- CONTRAST MEDIA
- X-RAY CONTRAST MEDIA, IODINATED
Synthesis Plan
FORMULA:C28H25ClFN5O2

SMILES: C[C@@]1(c2cccc(F)c2NC(=O)c2ccnc(Cl)c2)C2CCC(CC2)[C@@H]1c1nnc(-c2ccncc2)o1

BIRTHDAY: 2018-11-19T08:15:54.066784
ATC: C01D
- CARDIOVASCULAR SYSTEM
- CARDIAC THERAPY
- VASODILATORS USED IN CARDIAC DISEASES
Synthesis Plan
FORMULA:C17H14F3N5O

SMILES: Fc1cnccc1[C@@H]1C=Cc2c(ncn2[C@@H]2N=CO[C@H]3C[C@]32C(F)F)N1

BIRTHDAY: 2018-11-19T08:15:54.077520
ATC: A11H
- ALIMENTARY TRACT AND METABOLISM
- VITAMINS
- OTHER PLAIN VITAMIN PREPARATIONS
Synthesis Plan
FORMULA:C30H28F2N2O

SMILES: COc1ccc(-c2ccccc2[C@@]2(c3ccccc3F)Cc3cccc(F)c3[C@H](N)CCN2)cc1

BIRTHDAY: 2018-11-19T08:15:54.088498
ATC: A02B
- ALIMENTARY TRACT AND METABOLISM
- DRUGS FOR ACID RELATED DISORDERS
- DRUGS FOR PEPTIC ULCER AND GASTRO-OESOPHAGEAL REFLUX DISEASE (GORD)
Synthesis Plan
FORMULA:C18H15F3N4O

SMILES: Fc1cccc([C@@H]2C=Cc3ncn([C@@H]4N=C(C(F)F)O[C@@H]5C[C@@H]45)c3N2)c1

BIRTHDAY: 2018-11-19T08:15:54.098274
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C21H24ClFN4O

SMILES: CC(C)C12CNC(NC1)[C@@]2(C)c1c(F)cccc1NC(=O)c1ccncc1Cl

BIRTHDAY: 2018-11-19T08:15:54.107841
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C18H14ClFN6O

SMILES: C[C@]1(c2c(F)cccc2NC(=O)c2ccnc(Cl)c2)CN=Nc2cncn21

BIRTHDAY: 2018-11-19T08:15:54.118291
ATC: D08A
- DERMATOLOGICALS
- ANTISEPTICS AND DISINFECTANTS
- ANTISEPTICS AND DISINFECTANTS
Synthesis Plan
FORMULA:C17H17ClN4OS

SMILES: CC(C)c1ccc(NC(=O)c2ccncc2Cl)c2c1C=NSN2C

BIRTHDAY: 2018-11-19T08:15:54.135414
ATC: C10A
- CARDIOVASCULAR SYSTEM
- LIPID MODIFYING AGENTS
- LIPID MODIFYING AGENTS, PLAIN
Synthesis Plan
FORMULA:C20H22ClFN4OS

SMILES: C[C@]1(c2cccc(F)c2NC(=O)c2cnccc2Cl)CCC2(CC2)[C@@H](N)NS1

BIRTHDAY: 2018-11-19T08:15:54.145751
ATC: C03X
- CARDIOVASCULAR SYSTEM
- DIURETICS
- OTHER DIURETICS
Synthesis Plan
FORMULA:C16H20FNO

SMILES: CC1(C)CC2CC1(C(=O)NCc1ccccc1F)C2

BIRTHDAY: 2018-11-19T08:15:54.152563
ATC: C08C
- CARDIOVASCULAR SYSTEM
- CALCIUM CHANNEL BLOCKERS
- SELECTIVE CALCIUM CHANNEL BLOCKERS WITH MAINLY VASCULAR EFFECTS
Synthesis Plan
FORMULA:C17H15F2N5O

SMILES: FC(F)[C@@]12CN=CO[C@@]1(n1cnc3c1C=C(c1cccnc1)CN3)C2

BIRTHDAY: 2018-11-30T17:23:24.749707
ATC: R06A
- RESPIRATORY SYSTEM
- ANTIHISTAMINES FOR SYSTEMIC USE
- ANTIHISTAMINES FOR SYSTEMIC USE
Synthesis Plan
FORMULA:C27H29ClFN3O

SMILES: CN1CCCCc2ccccc2[C@](C)(c2cc(NC(=O)c3ccc(Cl)cn3)ccc2F)CC1

BIRTHDAY: 2018-11-30T17:23:24.777070
ATC: R03D
- RESPIRATORY SYSTEM
- DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES
- OTHER SYSTEMIC DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES
Synthesis Plan
FORMULA:C28H35ClF2N2O2

SMILES: C[C@]1(F)CCCCCCCC[C@](C)(c2cc(NC(=O)c3ccc(Cl)nc3)ccc2F)OC[C@H]2C[C@@H]21

BIRTHDAY: 2018-11-30T17:23:24.795830
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C33H36FNO5

SMILES: COc1ccccc1[C@@]1(c2ccccc2-c2cc(F)ccn2)CCCC(=O)C(C)(C)CCC(=O)CC(=O)COC1

BIRTHDAY: 2018-11-30T17:23:24.832771
ATC: N05A
- NERVOUS SYSTEM
- PSYCHOLEPTICS
- ANTIPSYCHOTICS
Synthesis Plan
FORMULA:C20H20ClFN4O5S

SMILES: C[C@@]1(c2ccc(NC(=O)c3cc(Cl)ccn3)cc2F)NS(=O)(=O)C(=N)[C@]2(CCCCO2)O1

BIRTHDAY: 2018-11-30T17:23:24.844055
ATC: A07A
- ALIMENTARY TRACT AND METABOLISM
- ANTIDIARRHEALS, INTESTINAL ANTIINFLAMMATORY/ANTIINFECTIVE AGENTS
- INTESTINAL ANTIINFECTIVES
Synthesis Plan
FORMULA:C18H19ClFN3OS2

SMILES: CN1S[C@@](C)(c2ccc(F)cc2NC(=O)c2ccncc2Cl)SC1(C)C

BIRTHDAY: 2018-11-30T17:23:24.853523
ATC: N05A
- NERVOUS SYSTEM
- PSYCHOLEPTICS
- ANTIPSYCHOTICS
Synthesis Plan
FORMULA:C28H38FN5O4

SMILES: CNC(=O)CC(C)(C)NC(=O)CC(C)(C)[C@@]1(N)N[C@@](c2ccccc2F)(c2ccccc2OC)N(C)C1=O

BIRTHDAY: 2018-11-30T17:23:24.864999
ATC: J05A
- ANTIINFECTIVES FOR SYSTEMIC USE
- ANTIVIRALS FOR SYSTEMIC USE
- DIRECT ACTING ANTIVIRALS
Synthesis Plan
FORMULA:C29H31F2N3O3

SMILES: COc1ccc([C@@]2(c3ccc(F)cc3)CN(CCCCCC(=O)NCc3ccc(F)cc3)C(=O)N2)cc1

BIRTHDAY: 2018-12-02T16:06:32.935649
ATC: N03A
- NERVOUS SYSTEM
- ANTIEPILEPTICS
- ANTIEPILEPTICS
Synthesis Plan
FORMULA:C7H11FN2O

SMILES: NC1=NC2(CC2)[C@H](CF)CO1

BIRTHDAY: 2018-12-02T16:06:32.950534
ATC: N07C
- NERVOUS SYSTEM
- OTHER NERVOUS SYSTEM DRUGS
- ANTIVERTIGO PREPARATIONS
Synthesis Plan
FORMULA:C26H23ClF2N2OS

SMILES: C[C@@]1(c2ccc(NC(=O)c3cncc(Cl)c3)c(F)c2)C[C@H]2CC[C@@](c3ccc(F)cc3)(C1)S2

BIRTHDAY: 2018-12-02T16:06:32.969392
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C28H30ClFN2O3

SMILES: C[C@]1(c2ccc(NC(=O)c3ccc(Cl)cn3)cc2F)CCCCCC[C@@H]2C(=O)C=CC(=O)[C@@H]2CC1

BIRTHDAY: 2018-12-02T16:06:32.988892
ATC: C03C
- CARDIOVASCULAR SYSTEM
- DIURETICS
- HIGH-CEILING DIURETICS
Synthesis Plan
FORMULA:C20H23F3N2

SMILES: C[C@]1(c2cc(F)ccc2F)CC[C@H](N)CCc2c(F)cccc2NC1

BIRTHDAY: 2018-12-02T16:06:32.997375
ATC: A10B
- ALIMENTARY TRACT AND METABOLISM
- DRUGS USED IN DIABETES
- BLOOD GLUCOSE LOWERING DRUGS, EXCL. INSULINS
Synthesis Plan
FORMULA:C33H35FO6

SMILES: COc1ccccc1-c1ccccc1[C@]1(c2ccccc2F)[C@@H]2CCO[C@@]13CCC[C@@H](O3)C(=O)COCCCO2

BIRTHDAY: 2018-12-02T16:06:33.010687
ATC: A02B
- ALIMENTARY TRACT AND METABOLISM
- DRUGS FOR ACID RELATED DISORDERS
- DRUGS FOR PEPTIC ULCER AND GASTRO-OESOPHAGEAL REFLUX DISEASE (GORD)
Synthesis Plan
FORMULA:C23H21ClFN5O4

SMILES: C[C@]1(c2ccc(NC(=O)c3ccc(Cl)cn3)cc2F)[C@@H]2CNC[C@@H]1N(c1coc(=O)nc1O)C2

BIRTHDAY: 2018-12-02T16:06:33.030546
ATC: C01C
- CARDIOVASCULAR SYSTEM
- CARDIAC THERAPY
- CARDIAC STIMULANTS EXCL. CARDIAC GLYCOSIDES
Synthesis Plan
FORMULA:C25H32ClF3N4O

SMILES: C[C@@]1(c2ccc(NC(=O)c3ccc(Cl)cn3)cc2F)CCCCCCCCCNCC(F)(F)N1

BIRTHDAY: 2018-12-02T16:06:33.056995
ATC: M01A
- MUSCULO-SKELETAL SYSTEM
- ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS
- ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS
Synthesis Plan
FORMULA:C17H15ClFN3O2

SMILES: C[C+]1C[C@@](C)(c2cc(NC(=O)c3ccc(Cl)cn3)ccc2F)O[N-]1

BIRTHDAY: 2018-12-02T16:06:33.065809
ATC: N05B
- NERVOUS SYSTEM
- PSYCHOLEPTICS
- ANXIOLYTICS
Synthesis Plan
FORMULA:C24H27ClFN3O

SMILES: CC(C)[C@]1(c2c(F)cccc2NC(=O)c2ccncc2Cl)[C@H]2CCN3[C@H](CC[C@@H]31)C2

BIRTHDAY: 2018-12-02T16:06:33.093741
ATC: V09X
- VARIOUS
- DIAGNOSTIC RADIOPHARMACEUTICALS
- OTHER DIAGNOSTIC RADIOPHARMACEUTICALS
Synthesis Plan
FORMULA:C14H12F2N4O

SMILES: FCC1=NC[C@@H]2C[C@]2(n2ccnc2-c2ccncc2F)O1

BIRTHDAY: 2018-12-02T16:06:33.102289
ATC: J05A
- ANTIINFECTIVES FOR SYSTEMIC USE
- ANTIVIRALS FOR SYSTEMIC USE
- DIRECT ACTING ANTIVIRALS
Synthesis Plan
FORMULA:C14H10ClF3N2O

SMILES: O=C(Nc1c(F)cccc1CC(F)F)c1ccnc(Cl)c1

BIRTHDAY: 2018-12-03T10:42:54.750379
ATC: N07C
- NERVOUS SYSTEM
- OTHER NERVOUS SYSTEM DRUGS
- ANTIVERTIGO PREPARATIONS
Synthesis Plan
FORMULA:C27H37ClFN5O2

SMILES: C[C@]1(c2c(F)cccc2NC(=O)c2ccnc(Cl)c2)CNCCCCNCCOCCCC2(CC2)N1

BIRTHDAY: 2018-12-03T10:42:54.762431
ATC: P03B
- ANTIPARASITIC PRODUCTS, INSECTICIDES AND REPELLENTS
- ECTOPARASITICIDES, INCL. SCABICIDES, INSECTICIDES AND REPELLENTS
- INSECTICIDES AND REPELLENTS
Synthesis Plan
FORMULA:C18H17F2N5O

SMILES: FC(F)C1=N[C@@H](n2cnc3c2C=C[C@H](c2ccccn2)N3)C2(CC2)CO1

BIRTHDAY: 2018-12-03T10:42:54.771923
ATC: L01D
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- CYTOTOXIC ANTIBIOTICS AND RELATED SUBSTANCES
Synthesis Plan
FORMULA:C21H21ClFN3OS

SMILES: C[C@@]1(c2cccc(F)c2NC(=O)c2ccncc2Cl)[C@H]2CN[C@H]1C1(CC1)SC2

BIRTHDAY: 2018-12-03T10:42:54.799203
ATC: C10A
- CARDIOVASCULAR SYSTEM
- LIPID MODIFYING AGENTS
- LIPID MODIFYING AGENTS, PLAIN
Synthesis Plan
FORMULA:C17H15F2N5O

SMILES: FC(F)[C@]12C[C@]1(n1cnc3c1CNC(c1cccnc1)=C3)COC=N2

BIRTHDAY: 2018-12-03T10:42:54.808890
ATC: C01B
- CARDIOVASCULAR SYSTEM
- CARDIAC THERAPY
- ANTIARRHYTHMICS, CLASS I AND III
Synthesis Plan
FORMULA:C26H23ClF2N2O2

SMILES: C[C@@]1(c2c(F)cccc2NC(=O)c2ccncc2Cl)[C@H]2CCC[C@@]1(c1cccc(F)c1)OC2

BIRTHDAY: 2018-12-03T10:42:54.820076
ATC: C10A
- CARDIOVASCULAR SYSTEM
- LIPID MODIFYING AGENTS
- LIPID MODIFYING AGENTS, PLAIN
Synthesis Plan
FORMULA:C29H22F3NO3

SMILES: COc1ccccc1-c1ccc([C@@]2(c3ccc(F)cc3)OCN(Cc3ccc(F)c(F)c3)C2=O)cc1

BIRTHDAY: 2018-12-03T10:42:54.847092
ATC: A10B
- ALIMENTARY TRACT AND METABOLISM
- DRUGS USED IN DIABETES
- BLOOD GLUCOSE LOWERING DRUGS, EXCL. INSULINS
Synthesis Plan
FORMULA:C25H34ClF3N6OS

SMILES: CC1(C)CNCC(F)(F)NCCNCCN[C@@](C)(c2cc(NC(=O)c3ccc(Cl)cn3)ccc2F)CS1

BIRTHDAY: 2018-12-03T10:42:54.858955
ATC: P02C
- ANTIPARASITIC PRODUCTS, INSECTICIDES AND REPELLENTS
- ANTHELMINTICS
- ANTINEMATODAL AGENTS
Synthesis Plan
FORMULA:C29H38ClFN6O3

SMILES: C[C@@]1(c2ccc(NC(=O)c3ccc(Cl)cn3)c(F)c2)C[C@H]2C[C@H](C1)[C@@]1(O)NC3(CNCCNCCN[C@@H]21)COC3

BIRTHDAY: 2018-12-03T10:42:54.871199
ATC: M01A
- MUSCULO-SKELETAL SYSTEM
- ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS
- ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS
Synthesis Plan
FORMULA:C28H32FN3O2S2

SMILES: COc1ccccc1-c1ccccc1[C@]1(c2cccc(F)c2)CCCNCCNCC(=O)[C@@H](N)SS1

BIRTHDAY: 2018-12-03T10:42:54.893076
ATC: P01B
- ANTIPARASITIC PRODUCTS, INSECTICIDES AND REPELLENTS
- ANTIPROTOZOALS
- ANTIMALARIALS
Synthesis Plan
FORMULA:C25H34ClFN4O

SMILES: C[C@]1(c2c(F)cccc2NC(=O)c2ccnc(Cl)c2)CNCCCCCCCCCCN1

BIRTHDAY: 2018-12-03T10:42:54.902832
ATC: C02D
- CARDIOVASCULAR SYSTEM
- ANTIHYPERTENSIVES
- ARTERIOLAR SMOOTH MUSCLE, AGENTS ACTING ON
Synthesis Plan
FORMULA:C18H20F2NO5P

SMILES: CO[PH]1(=O)(OCC(c2cccc(F)c2)c2cccc(F)c2)OC=C(N)CO1

BIRTHDAY: 2018-12-03T10:42:54.912658
ATC: G02A
- GENITO URINARY SYSTEM AND SEX HORMONES
- OTHER GYNECOLOGICALS
- UTEROTONICS
Synthesis Plan
FORMULA:C27H29ClFN3O2

SMILES: CN1CCCC[C@](C)(c2cc(NC(=O)c3cccnc3Cl)ccc2F)CCc2ccc(O)cc21

BIRTHDAY: 2018-12-03T10:42:54.922588
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C26H27NO2

SMILES: COc1cccc(C(=O)Nc2ccccc2C2(c3ccccc3)CCCCC2)c1

BIRTHDAY: 2018-12-03T10:42:54.930994
ATC: D07A
- DERMATOLOGICALS
- CORTICOSTEROIDS, DERMATOLOGICAL PREPARATIONS
- CORTICOSTEROIDS, PLAIN
Synthesis Plan
FORMULA:C20H28N2O6S

SMILES: CC(C)C[C@@H](NC(=O)c1cccc([C@]2(C)OCCS(=O)(=O)[C@]3(N)C[C@H]23)c1)C(=O)O

BIRTHDAY: 2018-12-03T19:11:19.690817
ATC: N07C
- NERVOUS SYSTEM
- OTHER NERVOUS SYSTEM DRUGS
- ANTIVERTIGO PREPARATIONS
Synthesis Plan
FORMULA:C17H15ClF3N5OS

SMILES: C[C@H]1NNC(=N)S[C@@]1(c1cc(NC(=O)c2ncccc2Cl)ccc1F)C(F)F

BIRTHDAY: 2018-12-03T19:11:19.709463
ATC: A03F
- ALIMENTARY TRACT AND METABOLISM
- DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS
- PROPULSIVES
Synthesis Plan
FORMULA:C25H24F2N2O3

SMILES: COc1cccc(C(=O)Nc2ccccc2[C@@H](C(=O)Nc2c(F)cccc2F)C(C)C)c1

BIRTHDAY: 2018-12-03T19:11:19.719393
ATC: C08C
- CARDIOVASCULAR SYSTEM
- CALCIUM CHANNEL BLOCKERS
- SELECTIVE CALCIUM CHANNEL BLOCKERS WITH MAINLY VASCULAR EFFECTS
Synthesis Plan
FORMULA:C41H73F3N14O2S2

SMILES: COc1ccncc1C(=O)Nc1c(F)cccc1[C@]1(CF)CNCCNCCNCCNCCNCCNCCNCCNCCNCCNCCN[C@](N)(F)C2(CC2)CSS1

BIRTHDAY: 2018-12-03T19:11:19.738947
ATC: A07X
- ALIMENTARY TRACT AND METABOLISM
- ANTIDIARRHEALS, INTESTINAL ANTIINFLAMMATORY/ANTIINFECTIVE AGENTS
- OTHER ANTIDIARRHEALS
Synthesis Plan
FORMULA:C19H13F4NO

SMILES: Fc1cccnc1-c1ccc(Cc2ccc(OC(F)(F)F)cc2)cc1

BIRTHDAY: 2018-12-03T19:11:19.747185
ATC: M01A
- MUSCULO-SKELETAL SYSTEM
- ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS
- ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS
Synthesis Plan
FORMULA:C28H19F3N2O4

SMILES: COc1ccccc1[C@@]1(c2ccccc2-c2ccncc2F)C(=O)OC(=O)N1Cc1c(F)cccc1F

BIRTHDAY: 2018-12-03T19:11:19.759061
ATC: V09G
- VARIOUS
- DIAGNOSTIC RADIOPHARMACEUTICALS
- CARDIOVASCULAR SYSTEM
Synthesis Plan
FORMULA:C20H21ClFN3O

SMILES: [CH2-][C@H]1C[C@@H]2C[N@H+]1C[C@@]2(C)c1c(F)cccc1NC(=O)c1ccnc(Cl)c1

BIRTHDAY: 2018-12-03T19:11:19.768403
ATC: P03B
- ANTIPARASITIC PRODUCTS, INSECTICIDES AND REPELLENTS
- ECTOPARASITICIDES, INCL. SCABICIDES, INSECTICIDES AND REPELLENTS
- INSECTICIDES AND REPELLENTS
Synthesis Plan
FORMULA:C29H32FNO3

SMILES: COc1ccccc1[C@@]1(c2ccccc2-c2cc(F)ccn2)CCCCCC(=O)CCCCO1

BIRTHDAY: 2018-12-03T19:11:19.779070
ATC: L02B
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ENDOCRINE THERAPY
- HORMONE ANTAGONISTS AND RELATED AGENTS
Synthesis Plan
FORMULA:C17H15F2N5O

SMILES: FC(F)[C@]12C[C@H]1COC(n1cnc3c1CNC=C3c1cccnc1)=N2

BIRTHDAY: 2018-12-03T19:11:19.788305
ATC: S01E
- SENSORY ORGANS
- OPHTHALMOLOGICALS
- ANTIGLAUCOMA PREPARATIONS AND MIOTICS
Synthesis Plan
FORMULA:C22H24ClFN2O2

SMILES: C[C@@]12COC[C@@H](C1)C[C@@](C)(c1cc(NC(=O)c3ncccc3Cl)ccc1F)C2

BIRTHDAY: 2018-12-03T19:11:19.816232
ATC: C09A
- CARDIOVASCULAR SYSTEM
- AGENTS ACTING ON THE RENIN-ANGIOTENSIN SYSTEM
- ACE INHIBITORS, PLAIN
Synthesis Plan
FORMULA:C25H24ClFN2O3S

SMILES: CC(C)c1cccc2c1S(=O)(=O)[C@](C)(c1cccc(F)c1NC(=O)c1ccncc1Cl)CC2

BIRTHDAY: 2018-12-03T19:11:19.842601
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C22H28ClFN6O

SMILES: C[C@@]1(c2cccc(NC(=O)c3ccncc3Cl)c2F)CNCCN[C@@H]2C[C@H]2NCCN1

BIRTHDAY: 2018-12-01T22:30:24.695543
ATC: P02C
- ANTIPARASITIC PRODUCTS, INSECTICIDES AND REPELLENTS
- ANTHELMINTICS
- ANTINEMATODAL AGENTS
Synthesis Plan
FORMULA:C32H28FN5O2

SMILES: COc1ccc([C@]2(c3ccc(-c4cccnc4F)cc3)C[C@@H]3CN[C@@H]2CN3C(=O)c2ccc(C#N)c(C)n2)cc1

BIRTHDAY: 2018-12-01T22:30:24.707534
ATC: C01B
- CARDIOVASCULAR SYSTEM
- CARDIAC THERAPY
- ANTIARRHYTHMICS, CLASS I AND III
Synthesis Plan
FORMULA:C20H13F4N5O2

SMILES: N=c1c(C(=O)NCc2ccc(F)c(F)c2)cc2c(=O)n3ccccc3nc2n1C(F)F

BIRTHDAY: 2018-12-01T22:30:24.726039
ATC: C02D
- CARDIOVASCULAR SYSTEM
- ANTIHYPERTENSIVES
- ARTERIOLAR SMOOTH MUSCLE, AGENTS ACTING ON
Synthesis Plan
FORMULA:C26H33ClF4N4O2

SMILES: C[C@]1(c2cccc(NC(=O)c3cnccc3Cl)c2F)CNCCCCNCC[C@@](C)(C(F)(F)F)COC1

BIRTHDAY: 2018-12-01T22:30:24.737556
ATC: C03X
- CARDIOVASCULAR SYSTEM
- DIURETICS
- OTHER DIURETICS
Synthesis Plan
FORMULA:C17H15F2N5O

SMILES: FC(F)[C@]12C[C@H]1OC=N[C@H]2n1cnc2c1NCC=C2c1ccncc1

BIRTHDAY: 2018-12-01T22:30:24.747921
ATC: A10B
- ALIMENTARY TRACT AND METABOLISM
- DRUGS USED IN DIABETES
- BLOOD GLUCOSE LOWERING DRUGS, EXCL. INSULINS
Synthesis Plan
FORMULA:C39H43F2NO2

SMILES: COc1ccc([C@@]2(c3ccc(-c4ccc(F)cn4)cc3)C[C@H]3C[C@H](C(C)(C)C)[C@@H]2C[C@@]3(c2ccc(F)cc2)C(C)(C)O)cc1

BIRTHDAY: 2018-12-01T22:30:24.759328
ATC: N06B
- NERVOUS SYSTEM
- PSYCHOANALEPTICS
- PSYCHOSTIMULANTS, AGENTS USED FOR ADHD AND NOOTROPICS
Synthesis Plan
FORMULA:C22H24ClN5O2S

SMILES: CC1(C)NC(C)(C)[C@@](C)(c2c(NC(=O)c3cnccc3Cl)ccc3c2NC3=O)SC1=N

BIRTHDAY: 2018-12-01T22:30:24.770047
ATC: V09G
- VARIOUS
- DIAGNOSTIC RADIOPHARMACEUTICALS
- CARDIOVASCULAR SYSTEM
Synthesis Plan
FORMULA:C18H17F2N5O

SMILES: FC(F)[C@@H]1COC(n2cnc3c2C=C(c2cccnc2)NC3)=NC12CC2

BIRTHDAY: 2018-12-01T22:30:24.788409
ATC: V08A
- VARIOUS
- CONTRAST MEDIA
- X-RAY CONTRAST MEDIA, IODINATED
Synthesis Plan
FORMULA:C17H15F2N5O

SMILES: FC(F)[C@]12C[C@H]1OC=N[C@H]2n1cnc2c1N[C@@H](c1ccccn1)C=C2

BIRTHDAY: 2018-12-01T22:30:24.798895
ATC: L01X
- ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
- ANTINEOPLASTIC AGENTS
- OTHER ANTINEOPLASTIC AGENTS
Synthesis Plan
FORMULA:C29H34FN3O4

SMILES: COc1ccc([C@]2(c3ccc(F)cc3)CN(CCCCCCC(=O)NCc3ccco3)C(=O)N2C)cc1

BIRTHDAY: 2018-12-01T22:30:24.817639
ATC: H05B
- SYSTEMIC HORMONAL PREPARATIONS, EXCL. SEX HORMONES AND INSULINS
- CALCIUM HOMEOSTASIS
- ANTI-PARATHYROID AGENTS
Synthesis Plan
FORMULA:C8H14N2O3S

SMILES: C[C@H]1C(=O)NC(C(C)(C)C)=NS1(=O)=O

BIRTHDAY: 2018-12-01T22:30:24.824678
ATC: S01L
- SENSORY ORGANS
- OPHTHALMOLOGICALS
- OCULAR VASCULAR DISORDER AGENTS
Synthesis Plan
FORMULA:C17H24FN5O

SMILES: CC1=C(c2cn(C3=NC4(CC4)[C@H](CF)CO3)cn2)CCNCCN1

BIRTHDAY: 2018-12-01T22:30:24.833263
ATC: C04A
- CARDIOVASCULAR SYSTEM
- PERIPHERAL VASODILATORS
- PERIPHERAL VASODILATORS
Synthesis Plan
FORMULA:C24H23FN6O

SMILES: COc1cccc(-c2ccccc2[C@]2(c3cccc(F)c3)N=N[C@]3(C)NC=NN3N2C)c1

BIRTHDAY: 2018-12-01T22:30:24.844692
ATC: C08E
- CARDIOVASCULAR SYSTEM
- CALCIUM CHANNEL BLOCKERS
- NON-SELECTIVE CALCIUM CHANNEL BLOCKERS
Synthesis Plan
FORMULA:C30H32FNO2

SMILES: COc1ccc(-c2ccc([C@@]3(c4ccc(F)cc4)C[C@H]4CCCC[C@@H](N)[C@@H](C3)C4=O)cc2)cc1

BIRTHDAY: 2018-12-01T22:30:24.854182
ATC: V09A
- VARIOUS
- DIAGNOSTIC RADIOPHARMACEUTICALS
- CENTRAL NERVOUS SYSTEM
Synthesis Plan
FORMULA:C24H23ClF2N2OSi

SMILES: CC1(C)C[SiH2]C[C@]1(c1cccc(F)c1)c1ccc(NC(=O)c2ccncc2Cl)c(F)c1

BIRTHDAY: 2018-12-01T22:30:24.864523
ATC: N05A
- NERVOUS SYSTEM
- PSYCHOLEPTICS
- ANTIPSYCHOTICS
Synthesis Plan
FORMULA:C22H24ClFN4O2

SMILES: C[C@@]1(c2cccc(F)c2NC(=O)c2ccncc2Cl)NC[C@H]2CCC[C@@]1(N)C(=O)C2

BIRTHDAY: 2018-12-01T22:30:24.874753
ATC: N07B
- NERVOUS SYSTEM
- OTHER NERVOUS SYSTEM DRUGS
- DRUGS USED IN ADDICTIVE DISORDERS
Synthesis Plan